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View Structure Prediction Details

Protein: gi|190408716
Organism: Saccharomyces cerevisiae RM11-1a
Length: 344 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190408716.

Description E-value Query
Range
Subject
Range
ATG14 - Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I (with Vps34/15/30p); Atg14p ta...
gi|207347655 - gi|207347655|gb|EDZ73755.1| YBR128Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190408716 - gi|190408716|gb|EDV11981.1| hypothetical protein SCRG_02840 [Saccharomyces cerevisiae RM11-1a]
ATG14_YEAST - Autophagy-related protein 14 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATG14 PE=1 ...
0.0 [1..344] [1..344]
SMC_METJA - Chromosome partition protein Smc OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JA...
SMC_METJA - Chromosome partition protein smc homolog OS=Methanocaldococcus jannaschii GN=MJ1643 PE=3 SV=2
0.005 [51..156] [241..349]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.005 [51..156] [241..349]

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Predicted Domain #1
Region A:
Residues: [1-174]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHCPICHHRA HVVYCAHCIN TSPSLLLKLK LDLILLKDEN KELNGKVEQI LNEAMNYDQL  60
   61 DIKRMEKKKD PLMNSLMKLD VLRMKKNNNL IRHRIEQLNE RIYSKRNHIS ELKVEIDNYK 120
  121 CYKVGTGTDK LREQVEISDA KNKLAQVSKI CESARDYKLN LLNNWFVIQK LQDN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.430 a.24.9 alpha-catenin/vinculin
View Download 0.380 d.2.1 Lysozyme-like
View Download 0.383 a.74.1 Cyclin-like
View Download 0.370 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.347 f.1.3 delta-Endotoxin (insectocide), N-terminal domain
View Download 0.326 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.273 a.118.9 ENTH/VHS domain
View Download 0.272 a.91.1 Regulator of G-protein signalling, RGS
View Download 0.265 c.57.1 Molybdenum cofactor biosynthesis proteins
View Download 0.260 c.37.1 P-loop containing nucleoside triphosphate hydrolases
View Download 0.244 c.66.1 S-adenosyl-L-methionine-dependent methyltransferases
View Download 0.236 a.74.1 Cyclin-like
View Download 0.235 a.4.5 "Winged helix" DNA-binding domain
View Download 0.217 a.123.1 Nuclear receptor ligand-binding domain
View Download 0.216 c.51.1 Anticodon-binding domain of Class II aaRS
View Download 0.210 a.22.1 Histone-fold
View Download 0.203 f.1.4 Bcl-2 inhibitors of programmed cell death

Predicted functions:

Term Confidence Notes
binding 1.84003218039855 bayes_pls_golite062009
protein binding 1.44233807327602 bayes_pls_golite062009
signal transducer activity 0.804943740914237 bayes_pls_golite062009
molecular transducer activity 0.804943740914237 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [175-344]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FQIPFAIAFQ PLISLKNFRI LPLAITNDSI NIMWKYISFF SDILMIKLPY TNKICEQPMF  60
   61 EFSDSIQTVV QRLIKLIINI LQICRHLKLV PSTPMDIPWL LDQYDVDGLF YNMVKRNKMK 120
  121 CRSVSLYWTF GMLYSMVLDN MNNPQRGHPA RRTAPPPTVT GPHDRWYVVG 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.689 0.239 autophagy a.39.1 EF-hand
View Download 0.652 0.177 autophagy b.40.4 Nucleic acid-binding proteins
View Download 0.579 0.144 autophagy a.1.1 Globin-like
View Download 0.552 0.068 autophagy a.25.1 Ferritin-like
View Download 0.552 0.002 autophagy a.167.1 Porin chaperone SurA, peptide-binding domain
View Download 0.689 N/A N/A a.39.1 EF-hand
View Download 0.652 N/A N/A b.40.4 Nucleic acid-binding proteins
View Download 0.579 N/A N/A a.1.1 Globin-like
View Download 0.552 N/A N/A a.167.1 Porin chaperone SurA, peptide-binding domain
View Download 0.552 N/A N/A a.25.1 Ferritin-like
View Download 0.523 N/A N/A a.1.1 Globin-like
View Download 0.513 N/A N/A a.1.1 Globin-like
View Download 0.495 N/A N/A a.1.1 Globin-like
View Download 0.466 N/A N/A d.19.1 MHC antigen-recognition domain
View Download 0.460 N/A N/A d.19.1 MHC antigen-recognition domain
View Download 0.450 N/A N/A a.1.1 Globin-like
View Download 0.436 N/A N/A a.39.1 EF-hand
View Download 0.432 N/A N/A a.1.1 Globin-like
View Download 0.413 N/A N/A a.7.1 Spectrin repeat
View Download 0.404 N/A N/A a.25.1 Ferritin-like
View Download 0.390 N/A N/A d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.390 N/A N/A a.7.1 Spectrin repeat
View Download 0.380 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.373 N/A N/A f.25.1 Cytochrome c oxidase subunit III-like
View Download 0.371 N/A N/A d.54.1 Enolase N-terminal domain-like
View Download 0.365 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.358 N/A N/A f.25.1 Cytochrome c oxidase subunit III-like
View Download 0.358 N/A N/A d.108.1 Acyl-CoA N-acyltransferases (Nat)
View Download 0.356 N/A N/A b.40.4 Nucleic acid-binding proteins
View Download 0.355 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.352 N/A N/A a.48.1 N-terminal domain of cbl (N-cbl)
View Download 0.351 N/A N/A a.74.1 Cyclin-like
View Download 0.343 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.343 N/A N/A a.97.1 An anticodon-binding domain of class I aminoacyl-tRNA synthetases
View Download 0.338 N/A N/A d.173.1 Methionine synthase activation domain-like
View Download 0.337 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.333 N/A N/A f.1.1 Colicin
View Download 0.324 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.322 N/A N/A a.39.1 EF-hand
View Download 0.313 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.309 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.307 N/A N/A a.72.1 Functional domain of the splicing factor Prp18
View Download 0.289 N/A N/A a.132.1 Heme oxygenase
View Download 0.289 N/A N/A d.2.1 Lysozyme-like
View Download 0.288 N/A N/A a.1.1 Globin-like
View Download 0.287 N/A N/A a.47.2 t-snare proteins
View Download 0.285 N/A N/A a.118.9 ENTH/VHS domain
View Download 0.280 N/A N/A a.73.1 Retrovirus capsid protein, N-terminal core domain
View Download 0.271 N/A N/A a.118.7 14-3-3 protein
View Download 0.270 N/A N/A a.1.1 Globin-like
View Download 0.269 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.268 N/A N/A f.35.1 Multidrug efflux transporter AcrB transmembrane domain
View Download 0.267 N/A N/A a.1.1 Globin-like
View Download 0.264 N/A N/A d.144.1 Protein kinase-like (PK-like)
View Download 0.262 N/A N/A a.26.1 4-helical cytokines
View Download 0.257 N/A N/A a.62.1 Hepatitis B viral capsid (hbcag)
View Download 0.256 N/A N/A c.116.1 alpha/beta knot
View Download 0.255 N/A N/A d.163.1 DNA breaking-rejoining enzymes
View Download 0.253 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.253 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.251 N/A N/A a.19.1 Fertilization protein
View Download 0.244 N/A N/A a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.243 N/A N/A d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.240 N/A N/A a.123.1 Nuclear receptor ligand-binding domain
View Download 0.239 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.237 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.234 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.234 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.233 N/A N/A d.58.39 Glutamyl tRNA-reductase catalytic, N-terminal domain
View Download 0.221 N/A N/A a.62.1 Hepatitis B viral capsid (hbcag)
View Download 0.218 N/A N/A a.1.1 Globin-like
View Download 0.216 N/A N/A a.26.1 4-helical cytokines
View Download 0.216 N/A N/A d.227.1 OsmC-like
View Download 0.215 N/A N/A a.74.1 Cyclin-like
View Download 0.214 N/A N/A c.60.1 Phosphoglycerate mutase-like
View Download 0.213 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.204 N/A N/A d.54.1 Enolase N-terminal domain-like
View Download 0.203 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle