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View Structure Prediction Details

Protein: gi|207342060
Organism: Saccharomyces cerevisiae AWRI1631
Length: 505 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|207342060.

Description E-value Query
Range
Subject
Range
HAS1 - ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched i...
gi|207342060 - gi|207342060|gb|EDZ69940.1| YMR290Cp-like protein [Saccharomyces cerevisiae AWRI1631]
gi|190408516 - gi|190408516|gb|EDV11781.1| RNA-dependent helicase [Saccharomyces cerevisiae RM11-1a]
gi|151945998 - gi|151945998|gb|EDN64230.1| helicase associated with set1 [Saccharomyces cerevisiae YJM789]
HAS1_YEAST - ATP-dependent RNA helicase HAS1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HAS1 PE=...
0.0 [1..505] [1..505]
DDX3_XENLA - Putative ATP-dependent RNA helicase an3 OS=Xenopus laevis GN=an3 PE=2 SV=1
0.0 [4..427] [183..619]
gi|13514813, gi|... - gi|2580552|gb|AAC51830.1| dead box, X isoform [Homo sapiens], gi|2580550|gb|AAC51829.1| dead box, X ...
0.0 [4..426] [142..577]
DDX3X_MOUSE - ATP-dependent RNA helicase DDX3X OS=Mus musculus GN=Ddx3x PE=1 SV=3
0.0 [4..426] [142..577]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
0.0 [4..427] [183..619]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [2..493] [68..569]

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Predicted Domain #1
Region A:
Residues: [1-259]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATPSNKRSR DSESTEEPVV DEKSTSKQNN AAPEGEQTTC VEKFEELKLS QPTLKAIEKM  60
   61 GFTTMTSVQA RTIPPLLAGR DVLGAAKTGS GKTLAFLIPA IELLHSLKFK PRNGTGIIVI 120
  121 TPTRELALQI FGVARELMEF HSQTFGIVIG GANRRQEAEK LMKGVNMLIA TPGRLLDHLQ 180
  181 NTKGFVFKNL KALIIDEADR ILEIGFEDEM RQIIKILPNE DRQSMLFSAT QTTKVEDLAR 240
  241 ISLRPGPLFI NVVPETDNS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 549.218487
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [260-410]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TADGLEQGYV VCDSDKRFLL LFSFLKRNQK KKIIVFLSSC NSVKYYAELL NYIDLPVLEL  60
   61 HGKQKQQKRT NTFFEFCNAE RGILICTDVA ARGLDIPAVD WIIQFDPPDD PRDYIHRVGR 120
  121 TARGTKGKGK SLMFLTPNEL GFLRYLKASK V

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 549.218487
Match: 1hv8A_
Description: Putative DEAD box RNA helicase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [411-505]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLNEYEFPEN KIANVQSQLE KLIKSNYYLH QTAKDGYRSY LQAYASHSLK TVYQIDKLDL  60
   61 AKVAKSYGFP VPPKVNITIG ASGKTPNTKR RKTHK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.523 a.1.1 Globin-like
View Download 0.609 a.74.1 Cyclin-like
View Download 0.660 a.60.2 RuvA domain 2-like
View Download 0.525 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.630 a.159.2 FF domain
View Download 0.512 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.511 a.4.5 "Winged helix" DNA-binding domain
View Download 0.510 a.74.1 Cyclin-like
View Download 0.502 a.74.1 Cyclin-like
View Download 0.470 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.438 a.61.1 Retroviral matrix proteins
View Download 0.437 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.392 a.4.5 "Winged helix" DNA-binding domain
View Download 0.320 c.26.3 UDP-glucose/GDP-mannose dehydrogenase C-terminal domain
View Download 0.316 a.59.1 PAH2 domain
View Download 0.307 a.74.1 Cyclin-like
View Download 0.303 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.300 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.290 a.44.1 Disulphide-bond formation facilitator (DSBA), insertion domain
View Download 0.279 a.77.1 DEATH domain
View Download 0.273 a.60.1 SAM/Pointed domain
View Download 0.270 a.61.1 Retroviral matrix proteins
View Download 0.261 b.40.4 Nucleic acid-binding proteins
View Download 0.257 a.60.8 HRDC-like
View Download 0.257 a.48.3 Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View Download 0.256 a.1.1 Globin-like
View Download 0.246 a.4.3 ARID-like
View Download 0.237 d.1.1 Microbial ribonucleases
View Download 0.232 a.64.1 Saposin
View Download 0.219 c.53.1 Resolvase-like
View Download 0.214 a.144.1 PABC (PABP) domain
View Download 0.213 a.81.1 N-terminal domain of DnaB helicase
View Download 0.213 a.69.3 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain
View Download 0.210 a.5.4 Elongation factor TFIIS domain 2
View Download 0.209 a.64.1 Saposin
View Download 0.207 d.55.1 Ribosomal protein L22
View Download 0.206 a.61.1 Retroviral matrix proteins
View Download 0.203 d.58.10 Acylphosphatase-like


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