YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|161362612, gi...
Organism:	Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7
Length:	196 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|161362612, gi....

Description	E-value	Query Range	Subject Range
gi\|192955120, gi... - gi\|75214869\|ref\|ZP_00713350.1\| COG0118: Glutamine amidotransferase [Escherichia coli E110019], gi\|19... gi\|194428759, gi... - gi\|75210033\|ref\|ZP_00710216.1\| COG0118: Glutamine amidotransferase [Escherichia coli B171], gi\|19442...	5.0E-46	[1..196]	[1..196]
gi\|77962463 - gi\|77962463\|ref\|ZP_00826283.1\| COG0118: Glutamine amidotransferase [Yersinia mollaretii ATCC 43969]	8.0E-46	[1..196]	[1..196]
gi\|77978865 - gi\|77978865\|ref\|ZP_00834289.1\| COG0118: Glutamine amidotransferase [Yersinia intermedia ATCC 29909]	1.0E-45	[1..196]	[1..196]
gi\|77975878 - gi\|77975878\|ref\|ZP_00831412.1\| COG0118: Glutamine amidotransferase [Yersinia frederiksenii ATCC 3364...	2.0E-45	[1..196]	[1..196]
gi\|77959283 - gi\|77959283\|ref\|ZP_00823304.1\| COG0118: Glutamine amidotransferase [Yersinia bercovieri ATCC 43970]	2.0E-45	[1..196]	[1..196]
gi\|16765405, gi\|... - gi\|16765405\|ref\|NP_461020.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella typhimur... gi\|207857510, gi... - gi\|207857510\|ref\|YP_002244161.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella ente... gi\|205272998, gi... - gi\|205353217\|ref\|YP_002227018.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella ente... gi\|62128288, gi\|... - gi\|62180655\|ref\|YP_217072.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enterica...	5.0E-45	[1..196]	[2..197]
gi\|85059104, gi\|... - gi\|85059104\|ref\|YP_454806.1\| imidazole glycerol phosphate synthase subunit HisH [Sodalis glossinidiu...	7.0E-45	[1..196]	[1..196]
gi\|189355492, gi... - gi\|189355492\|gb\|EDU73911.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|188014321, gi... - gi\|188014321\|gb\|EDU52443.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... EG10450 - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit / Imidazole glycerol phosp... HIS5_ECOL6 - Imidazole glycerol phosphate synthase subunit HisH OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 7... EG10450 - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit / Imidazole glycerol phosp... HIS5_SHISS - Imidazole glycerol phosphate synthase subunit HisH OS=Shigella sonnei (strain Ss046) GN=hisH PE=3 SV... gi\|208817155, gi... - gi\|208817155\|ref\|ZP_03258247.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|75514064, gi\|... - gi\|75514064\|ref\|ZP_00736394.1\| COG0118: Glutamine amidotransferase [Escherichia coli 53638], gi\|1884... gi\|208727400, gi... - gi\|208807599\|ref\|ZP_03249936.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|75259172, gi\|... - gi\|75259172\|ref\|ZP_00730520.1\| COG0118: Glutamine amidotransferase [Escherichia coli E22], gi\|193062... gi\|209396111, gi... - gi\|209396111\|ref\|YP_002271264.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|190909636, gi... - gi\|75242856\|ref\|ZP_00726562.1\| COG0118: Glutamine amidotransferase [Escherichia coli F11], gi\|191170... gi\|208818954, gi... - gi\|208818954\|ref\|ZP_03259274.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|215487245, gi... - gi\|215487245\|ref\|YP_002329676.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col... gi\|209919488, gi... - gi\|209919488\|ref\|YP_002293572.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col... HIS5_SHIBS - Imidazole glycerol phosphate synthase subunit HisH OS=Shigella boydii serotype 4 (strain Sb227) GN=h... gi\|218361354, gi... - gi\|218554586\|ref\|YP_002387499.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col... HIS5_SHIDS - Imidazole glycerol phosphate synthase subunit HisH OS=Shigella dysenteriae serotype 1 (strain Sd197)... gi\|218549437, gi... - gi\|218549437\|ref\|YP_002383228.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia fer... gi\|194420392, gi... - gi\|83571263\|ref\|ZP_00922704.1\| COG0118: Glutamine amidotransferase [Shigella dysenteriae 1012], gi\|1... gi\|187769010, gi... - gi\|187769010\|gb\|EDU32854.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|194424981, gi... - gi\|83588024\|ref\|ZP_00926649.1\| COG0118: Glutamine amidotransferase [Escherichia coli 101-1], gi\|1944... gi\|189361197, gi... - gi\|189361197\|gb\|EDU79616.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|89108844, gi\|... - gi\|89108844\|ref\|AP_002624.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subun... gi\|168788689, gi... - gi\|189371592\|gb\|EDU90008.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|237704479, gi... - gi\|237704479\|ref\|ZP_04534960.1\| imidazole glycerol phosphate synthase subunit hisH [Escherichia sp. ... gi\|91211309, gi\|... - gi\|91211309\|ref\|YP_541295.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia coli UT... gi\|115513350, gi... - gi\|117624226\|ref\|YP_853139.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia coli A... gi\|168782304, gi... - gi\|189000084\|gb\|EDU69070.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|238901214, gi... - gi\|238901214\|ref\|YP_002927010.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|190902231, gi... - gi\|75229116\|ref\|ZP_00715691.1\| COG0118: Glutamine amidotransferase [Escherichia coli B7A], gi\|191167... gi\|124530722, gi... - gi\|124530722\|ref\|ZP_01701279.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|169754578, gi... - gi\|170019650\|ref\|YP_001724604.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col... gi\|254593205, gi... - gi\|254793805\|ref\|YP_003078642.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|75177150, gi\|... - gi\|75177150\|ref\|ZP_00697248.1\| COG0118: Glutamine amidotransferase [Shigella boydii BS512], gi\|18773... gi\|189378497, gi... - gi\|189378497\|gb\|EDU96913.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|195939361 - gi\|195939361\|ref\|ZP_03084743.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia coli... gi\|169889489, gi... - gi\|170081654\|ref\|YP_001730974.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|110343828, gi... - gi\|110642236\|ref\|YP_669966.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia coli 5... HIS5_ECOL6 - Imidazole glycerol phosphate synthase subunit HisH OS=Escherichia coli O6 GN=hisH PE=3 SV=1 HIS5_ECOLI - Imidazole glycerol phosphate synthase subunit hisH (EC 2.4.2.-) (IGP synthase glutamine amidotransfe... gi\|218369374, gi... - gi\|218699388\|ref\|YP_002407017.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col... gi\|218695649, gi... - gi\|218695649\|ref\|YP_002403316.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col... gi\|168986347 - gi\|168986347\|dbj\|BAG11886.1\| imidazole glycerol phosphate synthase [Escherichia coli O55:H7] gi\|218705562, gi... - gi\|218705562\|ref\|YP_002413081.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col...	9.0E-45	[1..196]	[1..196]
HIS5_SHIFL - Imidazole glycerol phosphate synthase subunit HisH OS=Shigella flexneri GN=hisH PE=3 SV=1 gi\|24052430, gi\|... - gi\|24113408\|ref\|NP_707918.1\| imidazole glycerol phosphate synthase subunit HisH [Shigella flexneri 2... gi\|110615544, gi... - gi\|110805996\|ref\|YP_689516.1\| imidazole glycerol phosphate synthase subunit HisH [Shigella flexneri ... gi\|30063473, gi\|... - gi\|30063473\|ref\|NP_837644.1\| imidazole glycerol phosphate synthase subunit HisH [Shigella flexneri 2...	1.0E-44	[1..196]	[1..196]
HIS5_YERPE - Imidazole glycerol phosphate synthase subunit HisH OS=Yersinia pestis GN=hisH PE=3 SV=1 gi\|145598715, gi... - gi\|145598715\|ref\|YP_001162791.1\| imidazole glycerol phosphate synthase subunit HisH [Yersinia pestis... gi\|149366466, gi... - gi\|149366466\|ref\|ZP_01888500.1\| amidotransferase [Yersinia pestis CA88-4125], gi\|149290840\|gb\|EDM409... gi\|45441259, gi\|... - gi\|45441259\|ref\|NP_992798.1\| imidazole glycerol phosphate synthase subunit HisH [Yersinia pestis bio... gi\|21959502, gi\|... - gi\|22126505\|ref\|NP_669928.1\| imidazole glycerol phosphate synthase subunit HisH [Yersinia pestis KIM... gi\|115347297, gi... - gi\|218928686\|ref\|YP_002346561.1\| imidazole glycerol phosphate synthase subunit HisH [Yersinia pestis... HIS5_YERPS - Imidazole glycerol phosphate synthase subunit HisH OS=Yersinia pseudotuberculosis serotype I (strain... gi\|167470869 - gi\|167470869\|ref\|ZP_02335573.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|162421534, gi... - gi\|77636298\|ref\|ZP_00798373.1\| COG0118: Glutamine amidotransferase [Yersinia pestis Angola], gi\|1624... gi\|170024754, gi... - gi\|170024754\|ref\|YP_001721259.1\| imidazole glycerol phosphate synthase subunit HisH [Yersinia pseudo... gi\|77628775, gi\|... - gi\|77628775\|ref\|ZP_00791361.1\| COG0118: Glutamine amidotransferase [Yersinia pseudotuberculosis IP 3... gi\|186894981, gi... - gi\|186894981\|ref\|YP_001872093.1\| imidazole glycerol phosphate synthase subunit HisH [Yersinia pseudo... HIS5_YERPS - Imidazole glycerol phosphate synthase subunit HisH OS=Yersinia pseudotuberculosis GN=hisH PE=3 SV=1 gi\|229703658, gi... - gi\|229894260\|ref\|ZP_04509443.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|165924385, gi... - gi\|165924385\|ref\|ZP_02220217.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|229689246, gi... - gi\|229843638\|ref\|ZP_04463781.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|165939576, gi... - gi\|89105295\|ref\|ZP_01177817.1\| COG0118: Glutamine amidotransferase [Yersinia pestis biovar Orientali... gi\|165991793, gi... - gi\|166009238\|ref\|ZP_02230136.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|229697893, gi... - gi\|229841527\|ref\|ZP_04461686.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|108806837, gi... - gi\|108806837\|ref\|YP_650753.1\| imidazole glycerol phosphate synthase subunit HisH [Yersinia pestis An... gi\|167400184, gi... - gi\|167400184\|ref\|ZP_02305697.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|229902990, gi... - gi\|229902990\|ref\|ZP_04518106.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|166960212, gi... - gi\|167421727\|ref\|ZP_02313480.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|167424048, gi... - gi\|167424048\|ref\|ZP_02315801.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su...	2.0E-44	[1..196]	[1..196]

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Predicted Domain #1

Region A:
Residues: [1-196]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNVVILDTGC ANLSSVKSAV ARHGYTPVVS REAEIVLRAD KLFLPGVGTA QAAMDQLRER  60
   61 ELIDLIKACT QPVLGICLGM QLLGRRSEET RGVDLLNIIE QDVPKMTDFG LPLPHMGWNR 120
  121 VYPQAGNRLF QGIEDGAYFY FVHSYAMPVN PWTIAQCNYG EPFTAAVQKD NFFGVQFHPE 180
  181 RSGAAGAQLL KNFLEM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.0
Match:	1jvnA
Description:	Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF; GAT subunit, HisH, (or domain) of imidazoleglycerolphosphate synthase HisF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
imidazoleglycerol-phosphate synthase activity	8.34101262147614	bayes_pls_golite062009
ligase activity	1.70348758031146	bayes_pls_golite062009
catalytic activity	1.30391542469987	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	0.643287540591989	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.628648036096965	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: