YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|213427703
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. E02-1180
Length:	350 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|213427703.

Description	E-value	Query Range	Subject Range
gi\|62126962, gi\|... - gi\|62179329\|ref\|YP_215746.1\| 3-deoxy-7-phosphoheptulonate synthase [Salmonella enterica subsp. enter...	0.0	[1..350]	[44..393]
gi\|73854749, gi\|... - gi\|74311272\|ref\|YP_309691.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella sonnei Ss046], gi...	0.0	[1..350]	[1..350]
gi\|193069560, gi... - gi\|75235771\|ref\|ZP_00719926.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ...	0.0	[1..350]	[1..350]
gi\|75237090, gi\|... - gi\|75237090\|ref\|ZP_00721144.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|110640955, gi... - gi\|110640955\|ref\|YP_668683.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli 536], gi...	0.0	[1..350]	[1..350]
gi\|205327720, gi... - gi\|205327720\|gb\|EDZ14484.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Salmonella enteric... gi\|197290090, gi... - gi\|197290090\|gb\|EDY29447.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Salmonella enteric... gi\|161364372, gi... - gi\|161615008\|ref\|YP_001588973.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Salmonella enterica su... lcl\|NC_016856.1_... - [gene=aroG] [protein=phospho-2-dehydro-3-deoxyheptonate aldolase] [protein_id=YP_005236479.2] [locat... gi\|199602771, gi... - gi\|200390326\|ref\|ZP_03216937.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Salmonella ent... gi\|194734297, gi... - gi\|194734297\|ref\|YP_002113862.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Salmonella en... gi\|16764125, gi\|... - gi\|16764125\|ref\|NP_459740.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Salmonella typhimurium LT2... gi\|197248245, gi... - gi\|197248245\|ref\|YP_002145716.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Salmonella en...	0.0	[1..350]	[1..350]
AROG_ECO57 - Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive OS=Escherichia coli O157:H7 GN=aroG PE=3 ... gi\|238859808, gi... - gi\|238900012\|ref\|YP_002925808.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... EG10079 - 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine repressible / 3-deoxy-D-arabino-... gi\|242376509, gi... - gi\|251784236\|ref\|YP_002998540.1\| hypothetical protein B21_00696 [Escherichia coli BL21], gi\|24237650... gi\|15800463, gi\|... - gi\|15800463\|ref\|NP_286475.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli O157:H7 E... gi\|253976912, gi... - gi\|254287605\|ref\|YP_003053353.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... AROG_ECOLI - Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive (EC 2.5.1.54) (Phospho-2-keto-3-deoxyhept... gi\|253972718, gi... - gi\|254160817\|ref\|YP_003043925.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... gi\|254591304, gi... - gi\|254791904\|ref\|YP_003076741.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... gi\|168750246, gi... - gi\|188015532\|gb\|EDU53654.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|1651339, gi\|8... - gi\|89107605\|ref\|AP_001385.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine rep... gi\|13360241, gi\|... - gi\|15830036\|ref\|NP_308809.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli O157:H7 s... gi\|168763344, gi... - gi\|189366448\|gb\|EDU84864.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|168757043, gi... - gi\|189355850\|gb\|EDU74269.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|187768162, gi... - gi\|187768162\|gb\|EDU32006.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|189363458, gi... - gi\|189363458\|gb\|EDU81877.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|189373159, gi... - gi\|189373159\|gb\|EDU91575.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|168779242, gi... - gi\|189002923\|gb\|EDU71909.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|81240176, gi\|... - gi\|82776028\|ref\|YP_402375.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella dysenteriae Sd197... gi\|217326155, gi... - gi\|217326155\|ref\|ZP_03442239.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia co... EG10079 - 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine repressible / 3-deoxy-D-arabino-... gi\|81244585, gi\|... - gi\|82543174\|ref\|YP_407121.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella boydii Sb227], gi... gi\|209917998, gi... - gi\|209917998\|ref\|YP_002292082.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli SE11]... gi\|192926766, gi... - gi\|75256338\|ref\|ZP_00728008.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|75511356, gi\|... - gi\|75511356\|ref\|ZP_00734041.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|218694171, gi... - gi\|218694171\|ref\|YP_002401838.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli 55989... gi\|170020908, gi... - gi\|170020908\|ref\|YP_001725862.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli ATCC ... gi\|83584861, gi\|... - gi\|83584861\|ref\|ZP_00923520.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|168800814, gi... - gi\|189376981\|gb\|EDU95397.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O... gi\|195936742 - gi\|195936742\|ref\|ZP_03082124.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli O157:H... gi\|170080414, gi... - gi\|170080414\|ref\|YP_001729734.1\| 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase, phenylalanine... gi\|194412266, gi... - gi\|75209077\|ref\|ZP_00709335.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|208731490, gi... - gi\|208814842\|ref\|ZP_03256021.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia co... gi\|75228379, gi\|... - gi\|75228379\|ref\|ZP_00715027.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|208808417, gi... - gi\|208808417\|ref\|ZP_03250754.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia co... gi\|187427742, gi... - gi\|75175250\|ref\|ZP_00695560.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|124531871, gi... - gi\|124531871\|ref\|ZP_01701970.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Escherichia coli B], gi... gi\|209400570, gi... - gi\|209400570\|ref\|YP_002269381.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia c... gi\|75194907, gi\|... - gi\|75194907\|ref\|ZP_00704977.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ... gi\|208737562, gi... - gi\|208822077\|ref\|ZP_03262396.1\| 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia co...	0.0	[1..350]	[1..350]
gi\|30749575, gi\|... - gi\|30749576\|pdb\|1N8F\|D Chain D, Crystal Structure Of E24q Mutant Of Phenylalanine-Regulated 3-Deoxy-...	0.0	[1..350]	[1..350]
gi\|30040334, gi\|... - gi\|30062090\|ref\|NP_836261.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella flexneri 2a str. ... gi\|24111977, gi\|... - gi\|24111977\|ref\|NP_706487.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella flexneri 2a str. ... gi\|110614175, gi... - gi\|110804627\|ref\|YP_688147.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Shigella flexneri 5 str. ...	0.0	[1..350]	[1..350]
gi\|157154975, gi... - gi\|75189768\|ref\|ZP_00703035.1\| COG0722: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase ...	0.0	[1..350]	[1..350]
gi\|56128385, gi\|... - gi\|56414128\|ref\|YP_151203.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Salmonella enterica subsp.... gi\|197363050, gi... - gi\|197363050\|ref\|YP_002142687.1\| phospho-2-dehydro-3-deoxyheptonate aldolase [Salmonella enterica su...	0.0	[1..350]	[1..350]

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Predicted Domain #1

Region A:
Residues: [1-350]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNYQNDDLRI KEINELLPPV ALLEKFPATE NAANTVAHAR KAIHKILKGN DDRLLVVIGP  60
   61 CSIHDPAAAK EYAARLLALR DELQGELEIV MRVYFEKPRT TVGWKGLIND PHMDNSFQIN 120
  121 DGLRIARKLL LDINDSGLPA AGEFLDMITP QYLADLMSWG AIGARTTESQ VHRELASGLS 180
  181 CPVGFKNGTD GTIKVAIDAI NAAGAPHCFL SVTKWGHSAI VNTSGNGDCH IILRGGKAPN 240
  241 YSAQHVAEVK EGLIKAGLTP QVMIDFSHAN SCKQFQKQME VCADVCQQIA GGEKAIIGVM 300
  301 VESHLVEGNQ SLESGQPLTY GKSITDACIG WEDTDALLRQ LSAAVKARRG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	145.0
Match:	1gg1A
Description:	3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase, AroG)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
3-deoxy-7-phosphoheptulonate synthase activity	2.72022882819661	bayes_pls_golite062009
catalytic activity	2.67031204377352	bayes_pls_golite062009
lyase activity	0.740424046054758	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	0.719960432098845	bayes_pls_golite062009
oxo-acid-lyase activity	0.606352769346285	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	0.490222900376021	bayes_pls_golite062009
transferase activity	0.464721888799972	bayes_pls_golite062009
carbon-carbon lyase activity	0.36754360512349	bayes_pls_golite062009
3-deoxy-8-phosphooctulonate synthase activity	0.0356008407895519	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: