YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|168277370
Organism:	synthetic construct
Length:	662 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|168277370.

Description	E-value	Query Range	Subject Range
tr\|G3GSH5\|G3GSH5... - ATP-dependent RNA helicase DDX3X OS=Cricetulus griseus GN=I79_000589 PE=3 SV=1 gi\|20373098 - gi\|20373098\|dbj\|BAB91216.1\| RNA helicase [Mesocricetus auratus]	0.0	[1..662]	[1..662]
gi\|74006730, gi\|... - gi\|74006732\|ref\|XP_538003.2\| PREDICTED: similar to DEAD-box protein 3, X-chromosomal (Helicase-like ...	0.0	[1..662]	[1..662]
gi\|13514813, gi\|... - gi\|2580552\|gb\|AAC51830.1\| dead box, X isoform [Homo sapiens], gi\|2580550\|gb\|AAC51829.1\| dead box, X ...	0.0	[1..662]	[1..662]
DDX3X_MOUSE - ATP-dependent RNA helicase DDX3X OS=Mus musculus GN=Ddx3x PE=1 SV=3	0.0	[1..662]	[1..662]
gi\|109510438, gi... - gi\|109511507\|ref\|XP_001060162.1\| PREDICTED: similar to ATP-dependent RNA helicase DDX3X (DEAD box pr...	0.0	[1..662]	[1..662]
gi\|76659561 - gi\|76659561\|ref\|XP_869563.1\| PREDICTED: similar to DEAD-box protein 3, X-chromosomal (Helicase-like ...	0.0	[1..662]	[1..660]

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Predicted Domain #1

Region A:
Residues: [1-179]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHVAVENAL GLDQQFAGLD LNSSDNQSGG STASKGRYIP PHLRNREATK GFYDKDSSGW  60
   61 SSSKDKDAYS SFGSRSDSRG KSSFFSDRGS GSRGRFDDRG RSDYDGIGSR GDRSGFGKFE 120
  121 RGGNSRWCDK SDEDDWSKPL PPSERLEQEL FSGGNTGINF EKYDDIPVEA TGNNCPPHI

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [180-578]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESFSDVEMGE IIMGNIELTR YTRPTPVQKH AIPIIKEKRD LMACAQTGSG KTAAFLLPIL  60
   61 SQIYSDGPGE ALRAMKENGR YGRRKQYPIS LVLAPTRELA VQIYEEARKF SYRSRVRPCV 120
  121 VYGGADIGQQ IRDLERGCHL LVATPGRLVD MMERGKIGLD FCKYLVLDEA DRMLDMGFEP 180
  181 QIRRIVEQDT MPPKGVRHTM MFSATFPKEI QMLARDFLDE YIFLAVGRVG STSENITQKV 240
  241 VWVEESDKRS FLLDLLNATG KDSLTLVFVE TKKGADSLED FLYHEGYACT SIHGDRSQRD 300
  301 REEALHQFRS GKSPILVATA VAARGLDISN VKHVINFDLP SDIEEYVHRI GRTGRVGNLG 360
  361 LATSFFNERN INITKDLLDL LVEAKQEVPS WLENMAYEH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	98.045757
Match:	2i4iA
Description:	No description for 2i4iA was found.

Predicted Domain #3

Region A:
Residues: [579-662]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HYKGSSRGRS KSSRFSGGFG ARDYRQSSGA SSSSFSSSRA SSSRSGGGGH GSSRGFGGGG  60
   61 YGGFYNSDGY GGNYNSQGVD WWGN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	21.221849
Match:	1d2mA
Description:	Nucleotide excision repair enzyme UvrB
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits