YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|206711313, gi...
Organism:	Salmonella enterica subsp. enterica serovar Enteritidis str. P125109
Length:	334 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|206711313, gi....

Description	E-value	Query Range	Subject Range
gi\|77976467, gi\|... - gi\|77976467\|ref\|ZP_00831954.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Ye...	2.0E-69	[1..334]	[1..332]
gi\|145600845, gi... - gi\|145600845\|ref\|YP_001164921.1\| FtsH protease regulator HflC [Yersinia pestis Pestoides F], gi\|1452... gi\|149289988, gi... - gi\|150260580\|ref\|ZP_01917308.1\| putative membrane protein [Yersinia pestis CA88-4125], gi\|149289988\|... gi\|22124548, gi\|... - gi\|22124548\|ref\|NP_667971.1\| FtsH protease regulator HflC [Yersinia pestis KIM], gi\|21957347\|gb\|AAM8... gi\|25509641 - pir\|\|AH0046 probable membrane protein hflC [imported] - Yersinia pestis (strain CO92) gi\|165926803, gi... - gi\|165926803\|ref\|ZP_02222635.1\| HflC protein [Yersinia pestis biovar Orientalis str. F1991016], gi\|1... gi\|51594780, gi\|... - gi\|51594780\|ref\|YP_068971.1\| FtsH protease regulator HflC [Yersinia pseudotuberculosis IP 32953], gi... Q66FB2\|Q66FB2_YERPS - Putative membrane protein precursor - Yersinia pseudotuberculosis gi\|165989216, gi... - gi\|166011857\|ref\|ZP_02232755.1\| HflC protein [Yersinia pestis biovar Antiqua str. E1979001], gi\|1659... gi\|45435242, gi\|... - gi\|45440386\|ref\|NP_991925.1\| FtsH protease regulator HflC [Yersinia pestis biovar Microtus str. 9100... gi\|77632980, gi\|... - gi\|77632980\|ref\|ZP_00795141.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Ye... gi\|166213993, gi... - gi\|166213993\|ref\|ZP_02240028.1\| HflC protein [Yersinia pestis biovar Antiqua str. B42003004], gi\|166... gi\|77631427, gi\|... - gi\|77631427\|ref\|ZP_00794013.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Ye... gi\|167049856, gi... - gi\|167400488\|ref\|ZP_02305997.1\| HflC protein [Yersinia pestis biovar Antiqua str. UG05-0454], gi\|167... gi\|16120711, gi\|... - gi\|218927579\|ref\|YP_002345454.1\| FtsH protease regulator HflC [Yersinia pestis CO92], gi\|16120711\|re... gi\|167418832, gi... - gi\|167418832\|ref\|ZP_02310585.1\| HflC protein [Yersinia pestis biovar Orientalis str. MG05-1020], gi\|... gi\|229903935, gi... - gi\|229903935\|ref\|ZP_04519048.1\| modulator for HflB protease specific for phage lambda cII repressor ... gi\|89102916, gi\|... - gi\|89102916\|ref\|ZP_01175518.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Ye... gi\|108809898, gi... - gi\|108809898\|ref\|YP_653814.1\| FtsH protease regulator HflC [Yersinia pestis Antiqua], gi\|108781811\|g... gi\|167423354, gi... - gi\|167423354\|ref\|ZP_02315107.1\| HflC protein [Yersinia pestis biovar Mediaevalis str. K1973002], gi\|... gi\|169752544, gi... - gi\|170026010\|ref\|YP_001722515.1\| FtsH protease regulator HflC [Yersinia pseudotuberculosis YPIII], g... gi\|186893788, gi... - gi\|186893788\|ref\|YP_001870900.1\| FtsH protease regulator HflC [Yersinia pseudotuberculosis PB1/+], g... gi\|229842326, gi... - gi\|229842326\|ref\|ZP_04462481.1\| modulator for HflB protease specific for phage lambda cII repressor ... gi\|229696614, gi... - gi\|229840248\|ref\|ZP_04460407.1\| modulator for HflB protease specific for phage lambda cII repressor ... gi\|229836636, gi... - gi\|229836636\|ref\|ZP_04456802.1\| modulator for HflB protease specific for phage lambda cII repressor ...	2.0E-69	[1..334]	[1..332]
gi\|238787542, gi... - gi\|77973966\|ref\|ZP_00829509.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Ye...	2.0E-66	[17..334]	[17..334]
gi\|82779443, gi\|... - gi\|82779443\|ref\|YP_405792.1\| FtsH protease regulator HflC [Shigella dysenteriae Sd197], gi\|81243591\|...	9.0E-66	[17..334]	[17..334]
gi\|75236172, gi\|... - gi\|75242436\|ref\|ZP_00726198.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Es... gi\|192926346, gi... - gi\|75255902\|ref\|ZP_00727634.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Es... gi\|191165679, gi... - gi\|75231232\|ref\|ZP_00717639.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Es... gi\|192955825, gi... - gi\|75234276\|ref\|ZP_00718664.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Es... gi\|81247995, gi\|... - gi\|82546584\|ref\|YP_410531.1\| FtsH protease regulator HflC [Shigella boydii Sb227], gi\|81247995\|gb\|AB... gi\|85676926, gi\|... - gi\|89110895\|ref\|AP_004675.1\| modulator for HflB protease specific for phage lambda cII repressor [Es... gi\|188490469, gi... - gi\|75515414\|ref\|ZP_00737571.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Es... gi\|73858137, gi\|... - gi\|74314660\|ref\|YP_313079.1\| FtsH protease regulator HflC [Shigella sonnei Ss046], gi\|73858137\|gb\|AA... gi\|218363496, gi... - gi\|218556727\|ref\|YP_002389641.1\| FtsH protease regulator HflC [Escherichia coli IAI1], gi\|218363496\|... gi\|83585087, gi\|... - gi\|83585087\|ref\|ZP_00923740.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Es... gi\|218551445, gi... - gi\|218551445\|ref\|YP_002385237.1\| FtsH protease regulator HflC [Escherichia fergusonii ATCC 35469], g... gi\|218692509, gi... - gi\|218692509\|ref\|YP_002400721.1\| FtsH protease regulator HflC [Escherichia coli ED1a], gi\|218430073\|... gi\|218368103, gi... - gi\|218561334\|ref\|YP_002394247.1\| FtsH protease regulator HflC [Escherichia coli S88], gi\|218368103\|e... HFLC_SHIFL - Modulator of FtsH protease HflC OS=Shigella flexneri GN=hflC PE=3 SV=1 gi\|157163638, gi... - gi\|75198021\|ref\|ZP_00708091.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Es... gi\|218702872, gi... - gi\|218702872\|ref\|YP_002410501.1\| FtsH protease regulator HflC [Escherichia coli IAI39], gi\|218372858... gi\|24115530, gi\|... - gi\|24115530\|ref\|NP_710040.1\| FtsH protease regulator HflC [Shigella flexneri 2a str. 301], gi\|240548... gi\|75212276, gi\|... - gi\|75212276\|ref\|ZP_00712316.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Es... gi\|218697924, gi... - gi\|218697924\|ref\|YP_002405591.1\| FtsH protease regulator HflC [Escherichia coli 55989], gi\|218354656... HFLC_ECOL6 - Modulator of FtsH protease HflC OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=hf... gi\|187430961, gi... - gi\|75179454\|ref\|ZP_00699458.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Sh... gi\|30065547, gi\|... - gi\|30065547\|ref\|NP_839718.1\| FtsH protease regulator HflC [Shigella flexneri 2a str. 2457T], gi\|3004... gi\|157155878, gi... - gi\|75188886\|ref\|ZP_00702153.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Es... gi\|218707786, gi... - gi\|218707786\|ref\|YP_002415305.1\| FtsH protease regulator HflC [Escherichia coli UMN026], gi\|21843488... EG10435 - HflB protease modulator specific for phage lambda cII repressor / Membrane bound protease complex, w... HFLC_ECOLI - Protein hflC (EC 3.4.-.-) - Escherichia coli gi\|189357791, gi... - gi\|189357791\|gb\|EDU76210.1\| HflC protein [Escherichia coli O157:H7 str. EC4401], gi\|168754744\|ref\|ZP... gi\|227836355, gi... - gi\|227886782\|ref\|ZP_04004587.1\| FtsH protease regulator HflC [Escherichia coli 83972], gi\|227836355\|... gi\|168751475, gi... - gi\|188014499\|gb\|EDU52621.1\| HflC protein [Escherichia coli O157:H7 str. EC4113], gi\|168751475\|ref\|ZP... gi\|237703842, gi... - gi\|237703842\|ref\|ZP_04534323.1\| phage lambda cII repressor [Escherichia sp. 3_2_53FAA], gi\|226901754... gi\|189364336, gi... - gi\|189364336\|gb\|EDU82755.1\| HflC protein [Escherichia coli O157:H7 str. EC4486], gi\|168766452\|ref\|ZP... gi\|238903282, gi... - gi\|238903282\|ref\|YP_002929078.1\| modulator for HflB protease specific for phage lambda cII repressor... gi\|168760415, gi... - gi\|189368896\|gb\|EDU87312.1\| HflC protein [Escherichia coli O157:H7 str. EC4501], gi\|168760415\|ref\|ZP... gi\|242379697, gi... - gi\|251787424\|ref\|YP_003001728.1\| hypothetical protein B21_04004 [Escherichia coli BL21], gi\|24237969... gi\|254290854, gi... - gi\|254290854\|ref\|YP_003056602.1\| modulator for HflB protease specific for phage lambda cII repressor... gi\|226840295, gi... - gi\|254037189\|ref\|ZP_04871266.1\| protease specific for phage lambda cII repressor [Escherichia sp. 1_... gi\|253976005, gi... - gi\|254164104\|ref\|YP_003047212.1\| modulator for HflB protease specific for phage lambda cII repressor... gi\|254595594, gi... - gi\|254796194\|ref\|YP_003081031.1\| modulator for HflB protease specific for phage lambda cII repressor... HFLC_ECO57 - Modulator of FtsH protease HflC OS=Escherichia coli O157:H7 GN=hflC PE=3 SV=1 gi\|208728226, gi... - gi\|208808425\|ref\|ZP_03250762.1\| HflC protein [Escherichia coli O157:H7 str. EC4206], gi\|208728226\|gb... EG10435 - HflB protease modulator specific for phage lambda cII repressor / Membrane bound protease complex, w... gi\|195935965 - gi\|195935965\|ref\|ZP_03081347.1\| FtsH protease regulator HflC [Escherichia coli O157:H7 str. EC4024] gi\|12519160, gi\|... - gi\|15804764\|ref\|NP_290805.1\| FtsH protease regulator HflC [Escherichia coli O157:H7 EDL933], gi\|1251... gi\|208741470, gi... - gi\|208821347\|ref\|ZP_03261667.1\| HflC protein [Escherichia coli O157:H7 str. EC4042], gi\|208741470\|gb... gi\|208734412, gi... - gi\|208813135\|ref\|ZP_03254464.1\| HflC protein [Escherichia coli O157:H7 str. EC4045], gi\|208734412\|gb... gi\|209921663, gi... - gi\|209921663\|ref\|YP_002295747.1\| FtsH protease regulator HflC [Escherichia coli SE11], gi\|209914922\|... gi\|209397742, gi... - gi\|209397742\|ref\|YP_002273717.1\| HflC protein [Escherichia coli O157:H7 str. EC4115], gi\|209159142\|g... gi\|217322569, gi... - gi\|217326348\|ref\|ZP_03442432.1\| HflC protein [Escherichia coli O157:H7 str. TW14588], gi\|217322569\|g... gi\|215489519, gi... - gi\|215489519\|ref\|YP_002331950.1\| FtsH protease regulator HflC [Escherichia coli O127:H6 str. E2348/6... gi\|168780605, gi... - gi\|189001715\|gb\|EDU70701.1\| HflC protein [Escherichia coli O157:H7 str. EC4076], gi\|168780605\|ref\|ZP... gi\|168774114, gi... - gi\|187770255\|gb\|EDU34099.1\| HflC protein [Escherichia coli O157:H7 str. EC4196], gi\|168774114\|ref\|ZP... gi\|168801828, gi... - gi\|189376089\|gb\|EDU94505.1\| HflC protein [Escherichia coli O157:H7 str. EC508], gi\|168801828\|ref\|ZP_... HFLC_ECOL6 - Protein HflC OS=Escherichia coli O6 GN=hflC PE=3 SV=1 gi\|168784810, gi... - gi\|189374746\|gb\|EDU93162.1\| HflC protein [Escherichia coli O157:H7 str. EC869], gi\|168784810\|ref\|ZP_... gi\|169891456, gi... - gi\|170083621\|ref\|YP_001732941.1\| modulator for HflB protease specific for phage lambda cII repressor... gi\|170021815, gi... - gi\|170021815\|ref\|YP_001726769.1\| FtsH protease regulator HflC [Escherichia coli ATCC 8739], gi\|16975... gi\|194434594, gi... - gi\|194434594\|ref\|ZP_03066851.1\| HflC protein [Shigella dysenteriae 1012], gi\|194417179\|gb\|EDX33291.1... gi\|170521014, gi... - gi\|170683296\|ref\|YP_001746570.1\| HflC protein [Escherichia coli SMS-3-5], gi\|170521014\|gb\|ACB19192.1... gi\|15834405, gi\|... - gi\|15834405\|ref\|NP_313178.1\| FtsH protease regulator HflC [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|115515646, gi... - gi\|117626522\|ref\|YP_859845.1\| FtsH protease regulator HflC [Escherichia coli APEC O1], gi\|115515646\|... gi\|110346124, gi... - gi\|110644532\|ref\|YP_672262.1\| FtsH protease regulator HflC [Escherichia coli 536], gi\|110346124\|gb\|A... gi\|124500676, gi... - gi\|124528234\|ref\|ZP_01699558.1\| HflC protein [Escherichia coli B], gi\|124500676\|gb\|EAY48146.1\| HflC ... gi\|110617641, gi... - gi\|110808093\|ref\|YP_691613.1\| FtsH protease regulator HflC [Shigella flexneri 5 str. 8401], gi\|11061... gi\|91075298, gi\|... - gi\|91213724\|ref\|YP_543710.1\| FtsH protease regulator HflC [Escherichia coli UTI89], gi\|91075298\|gb\|A...	1.0E-65	[17..334]	[17..334]
gi\|238718602, gi... - gi\|77961302\|ref\|ZP_00825143.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Ye...	3.0E-65	[16..334]	[16..332]
gi\|50122851, gi\|... - gi\|50122851\|ref\|YP_052018.1\| FtsH protease regulator HflC [Pectobacterium atrosepticum SCRI1043], gi...	2.0E-64	[1..329]	[1..323]
gi\|238784770, gi... - gi\|77957809\|ref\|ZP_00821856.1\| COG0330: Membrane protease subunits, stomatin/prohibitin homologs [Ye...	2.0E-64	[16..334]	[16..332]
gi\|33519560, gi\|... - gi\|33519560\|ref\|NP_878392.1\| FtsH protease regulator HflC [Candidatus Blochmannia floridanus], gi\|33...	2.0E-61	[1..330]	[2..335]
gi\|84778838, gi\|... - gi\|85058318\|ref\|YP_454020.1\| FtsH protease regulator HflC [Sodalis glossinidius str. 'morsitans'], g...	3.0E-61	[17..330]	[17..330]

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Predicted Domain #1

Region A:
Residues: [1-214]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRKSVIAIII IVLVVLYMSV FVVKEGERGI TLRFGKVLRD DENKPLVYAP GLHFKIPFIE  60
   61 SVKMLDARIQ TMDNQADRFV TKEKKDLIVD SYIKWRISDF SRYYLATGGG DISQAEVLLK 120
  121 RKFSDRLRSE IGRLDVKDIV TDSRGRLTLE VRDALNSGSA GTDDEVATPA ADDAIAEAAE 180
  181 RVTAETKGKV PVINPNSMAA LGIEVVDVRI KQIN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.221849
Match:	1winA
Description:	Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.46226529578211	bayes_pls_golite062009
protein binding	0.769979871341236	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [215-334]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPTEVSEAIY NRMRAEREAV ARRHRSQGQE EAEKLRAAAD YEVTKTLAEA ERQGRIMRGE  60
   61 GDAEAAKLFA DAFSQDPDFY AFIRSLRAYE KSFEGNQDVM VLSPDSDFFR YMKTPSSTTR 120
  121

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: