YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|149243498, gi...
Organism:	Mycobacterium tuberculosis
Length:	174 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|149243498, gi....

Description	E-value	Query Range	Subject Range
DUT_HAEI8 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae (strain 86-028NP) GN=dut ... gi\|145274548, gi... - gi\|145640622\|ref\|ZP_01796205.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... DUT_HAEIG - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae (strain PittGG) GN=dut PE... DUT_HAEIE - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae (strain PittEE) GN=dut PE... gi\|42631278 - gi\|42631278\|ref\|ZP_00156816.1\| COG0756: dUTPase [Haemophilus influenzae R2866] gi\|145640622 - gi\|145640622\|ref\|ZP_01796205.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... DUT_HAEIN - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae (strain ATCC 51907 / DSM ... gi\|145272552, gi... - gi\|145638223\|ref\|ZP_01793833.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... gi\|229811018, gi... - gi\|229846014\|ref\|ZP_04466126.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... gi\|145269511, gi... - gi\|145637259\|ref\|ZP_01792920.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Haemophilus influe... DUT_HAEIN - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Haemophilus influenzae GN=dut PE=3 SV=1	188.0	[0..18]	[171..1]
gi\|46129100 - gi\|46129100\|ref\|ZP_00155752.2\| COG0756: dUTPase [Haemophilus influenzae R2846]	186.0	[0..18]	[171..1]
gi\|148263965, gi... - gi\|88937869\|ref\|ZP_01143404.1\| DeoxyUTP pyrophosphatase subfamily 1 [Geobacter uraniumreducens Rf4],...	183.0	[0..18]	[170..15]
gi\|77961979 - gi\|77961979\|ref\|ZP_00825806.1\| COG0756: dUTPase [Yersinia mollaretii ATCC 43969]	182.0	[0..18]	[171..2]
gi\|165926111, gi... - gi\|165926111\|ref\|ZP_02221943.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi... gi\|229839896, gi... - gi\|229839896\|ref\|ZP_04460055.1\| deoxyuridinetriphosphatase [Yersinia pestis biovar Orientalis str. P... DUT_YERPG - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Yersinia pestis bv. Antiqua (strain Angola) GN=d... gi\|229706607, gi... - gi\|229836159\|ref\|ZP_04456327.1\| deoxyuridinetriphosphatase [Yersinia pestis Pestoides A], gi\|2297066... gi\|115345879, gi... - gi\|218927268\|ref\|YP_002345143.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis C... gi\|229678611, gi... - gi\|229904493\|ref\|ZP_04519604.1\| deoxyuridinetriphosphatase [Yersinia pestis Nepal516], gi\|229678611\|... DUT_YERPE - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Yersinia pestis GN=dut PE=3 SV=1 DUT_YERPS - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Yersinia pseudotuberculosis serotype I (strain I... gi\|229690288, gi... - gi\|229841978\|ref\|ZP_04462133.1\| deoxyuridinetriphosphatase [Yersinia pestis biovar Orientalis str. I... gi\|167402097, gi... - gi\|167402097\|ref\|ZP_02307574.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi... gi\|166213714, gi... - gi\|166213714\|ref\|ZP_02239749.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi... gi\|166011436, gi... - gi\|166011436\|ref\|ZP_02232334.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi... gi\|165936135, gi... - gi\|165936135\|ref\|ZP_02224704.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi... gi\|150260889, gi... - gi\|150260889\|ref\|ZP_01917617.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis CA... DUT_YERP3 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Yersinia pseudotuberculosis serotype O:1b (strai... DUT_YERPS - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Yersinia pseudotuberculosis GN=dut PE=3 SV=1 gi\|167054366, gi... - gi\|167426677\|ref\|ZP_02318430.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi... gi\|167419027, gi... - gi\|167419027\|ref\|ZP_02310780.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis bi...	182.0	[0..18]	[171..1]
gi\|21956756, gi\|... - gi\|22124014\|ref\|NP_667437.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis KIM],... gi\|45439913, gi\|... - gi\|45439913\|ref\|NP_991452.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis biova...	182.0	[0..15]	[171..1]
gi\|108813963, gi... - gi\|108813963\|ref\|YP_649730.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis Nepa... gi\|108809486, gi... - gi\|108809486\|ref\|YP_653402.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis Anti... gi\|145212794, gi... - gi\|145601098\|ref\|YP_001165174.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pestis P... gi\|89103897 - gi\|89103897\|ref\|ZP_01176457.1\| COG0756: dUTPase [Yersinia pestis biovar Orientalis str. IP275] gi\|77634074 - gi\|77634074\|ref\|ZP_00796183.1\| COG0756: dUTPase [Yersinia pestis Angola] gi\|170026364, gi... - gi\|170026364\|ref\|YP_001722869.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pseudotu... gi\|117671896, gi... - gi\|77630875\|ref\|ZP_00793461.1\| COG0756: dUTPase [Yersinia pseudotuberculosis IP 31758], gi\|117671896... gi\|186893390, gi... - gi\|186893390\|ref\|YP_001870502.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Yersinia pseudotu...	181.0	[0..18]	[171..2]
DUT_ECOK1 - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli O1:K1 / APEC GN=dut PE=3 SV=1 gi\|237703411, gi... - gi\|237703411\|ref\|ZP_04533892.1\| deoxyuridine 5'-triphosphate nucleotidohydrolase [Escherichia sp. 3_... DUT_ECOUT - Deoxyuridine 5'-triphosphate nucleotidohydrolase OS=Escherichia coli (strain UTI89 / UPEC) GN=dut PE...	181.0	[0..18]	[171..2]
gi\|77972441 - gi\|77972441\|ref\|ZP_00828007.1\| COG0756: dUTPase [Yersinia frederiksenii ATCC 33641]	181.0	[0..18]	[171..2]
gi\|77958458 - gi\|77958458\|ref\|ZP_00822491.1\| COG0756: dUTPase [Yersinia bercovieri ATCC 43970]	181.0	[0..18]	[171..2]

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Predicted Domain #1

Region A:
Residues: [1-174]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSSHHHHHH SSGLVPRGSH MSTTLAIVRL DPGLPLPSRA HDGDAGVDLY SAEDVELAPG  60
   61 RRALVRTGVA VAVPFGMVGL VHPRSGLATR VGLSIVNSPG TIDAGYRGEI KVALINLDPA 120
  121 APIVVHRGDR IAQLLVQRVE LVELVEVSSF DEAGLASTSR GDGGHGSSGG HASL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	41.522879
Match:	1sixA
Description:	Mycobacterium tuberculosis dUTPase complexed with magnesium and alpha,beta-imido-dUTP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
dUTP diphosphatase activity	5.07554938490832	bayes_pls_golite062009
nucleoside-triphosphate diphosphatase activity	5.05238695583615	bayes_pls_golite062009
catalytic activity	2.08712526567445	bayes_pls_golite062009
hydrolase activity	0.832243246932065	bayes_pls_golite062009
dCTP deaminase activity	0.209566579785439	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: