YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|168759707, gi...
Organism:	Escherichia coli O157:H7 str. EC4501
Length:	155 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|168759707, gi....

Description	E-value	Query Range	Subject Range
gi\|226902644, gi... - gi\|237703380\|ref\|ZP_04533861.1\| preprotein translocase subunit SecB [Escherichia sp. 3_2_53FAA], gi\|... gi\|91213124, gi\|... - gi\|91213124\|ref\|YP_543110.1\| preprotein translocase subunit SecB [Escherichia coli UTI89], gi\|910746... gi\|115515011, gi... - gi\|117625887\|ref\|YP_859210.1\| preprotein translocase subunit SecB [Escherichia coli APEC O1], gi\|115...	258.0	[0..1]	[155..21]
gi\|26110683, gi\|... - gi\|26250254\|ref\|NP_756294.1\| export protein SecB [Escherichia coli CFT073], gi\|26110683\|gb\|AAN82868....	257.0	[0..1]	[155..21]
gi\|238910264 - gi\|238910264\|ref\|ZP_04654101.1\| preprotein translocase subunit SecB [Salmonella enterica subsp. ente... gi\|213852184 - gi\|213852184\|ref\|ZP_03381716.1\| preprotein translocase subunit SecB [Salmonella enterica subsp. ente... gi\|213999711 - gi\|213999711\|ref\|ZP_03410446.1\| preprotein translocase subunit SecB [Salmonella enterica subsp. ente... SECB_SALPC - Protein-export protein SecB OS=Salmonella paratyphi C (strain RKS4594) GN=secB PE=3 SV=1 SECB_SALEP - Protein-export protein SecB OS=Salmonella enteritidis PT4 (strain P125109) GN=secB PE=3 SV=1 gi\|213163819 - gi\|213163819\|ref\|ZP_03349529.1\| preprotein translocase subunit SecB [Salmonella enterica subsp. ente... gi\|213427154 - gi\|213427154\|ref\|ZP_03359904.1\| preprotein translocase subunit SecB [Salmonella enterica subsp. ente... gi\|213647900 - gi\|213647900\|ref\|ZP_03377953.1\| preprotein translocase subunit SecB [Salmonella enterica subsp. ente... SECB_SALTY - Protein-export protein SecB OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=secB ... gi\|29144098, gi\|... - gi\|29144098\|ref\|NP_807440.1\| preprotein translocase subunit SecB [Salmonella enterica subsp. enteric... SECB_SALTI - Protein-export protein SecB OS=Salmonella typhi GN=secB PE=3 SV=1 gi\|16762609 - gi\|16762609\|ref\|NP_458226.1\| preprotein translocase subunit SecB [Salmonella enterica subsp. enteric... SECB_SALCH - Protein-export protein SecB OS=Salmonella choleraesuis (strain SC-B67) GN=secB PE=3 SV=1 SECB_SALPA - Protein-export protein SecB OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=secB PE=3 SV=1 gi\|205325795, gi... - gi\|205325795\|gb\|EDZ13634.1\| protein-export chaperone SecB [Salmonella enterica subsp. enterica serov... gi\|205327803, gi... - gi\|205327803\|gb\|EDZ14567.1\| protein-export chaperone SecB [Salmonella enterica subsp. enterica serov... gi\|205333204, gi... - gi\|205333204\|gb\|EDZ19968.1\| protein-export chaperone SecB [Salmonella enterica subsp. enterica serov... SECB_SALAR - Protein-export protein SecB OS=Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) GN=se... SECB_SALPB - Protein-export protein SecB OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=secB PE=3 SV=... SECB_SALCH - Protein-export protein secB OS=Salmonella choleraesuis GN=secB PE=3 SV=1 SECB_SALDC - Protein-export protein SecB OS=Salmonella dublin (strain CT_02021853) GN=secB PE=3 SV=1 SECB_SALPA - Protein-export protein secB OS=Salmonella paratyphi A GN=secB PE=3 SV=1 gi\|200386846, gi... - gi\|200386846\|ref\|ZP_03213458.1\| protein-export chaperone SecB [Salmonella enterica subsp. enterica s... SECB_SALTI - Protein-export protein secB OS=Salmonella typhi GN=secB PE=3 SV=1 gi\|204928580, gi... - gi\|204928580\|ref\|ZP_03219779.1\| protein-export chaperone SecB [Salmonella enterica subsp. enterica s... SECB_SALTY - Protein-export protein secB OS=Salmonella typhimurium GN=secB PE=3 SV=1 SECB_SALG2 - Protein-export protein SecB OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=secB PE=3 SV=1 SECB_SALSV - Protein-export protein SecB OS=Salmonella schwarzengrund (strain CVM19633) GN=secB PE=3 SV=1 SECB_SALA4 - Protein-export protein SecB OS=Salmonella agona (strain SL483) GN=secB PE=3 SV=1 gi\|197262068, gi... - gi\|197262068\|ref\|ZP_03162142.1\| protein-export chaperone SecB [Salmonella enterica subsp. enterica s... SECB_SALPB - Protein-export protein secB OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=secB PE=3 SV=... SECB_SALPK - Protein-export protein SecB OS=Salmonella paratyphi A (strain AKU_12601) GN=secB PE=3 SV=1 gi\|205344440, gi... - gi\|205344440\|gb\|EDZ31204.1\| protein-export chaperone SecB [Salmonella enterica subsp. enterica serov... SECB_SALNS - Protein-export protein SecB OS=Salmonella newport (strain SL254) GN=secB PE=3 SV=1 SECB_SALHS - Protein-export protein SecB OS=Salmonella heidelberg (strain SL476) GN=secB PE=3 SV=1 SECB_SALTY - Protein-export protein secB OS=Salmonella typhimurium GN=secB PE=3 SV=1 lcl\|NC_016856.1_... - [gene=secB] [protein=preprotein translocase subunit SecB] [protein_id=YP_005239941.1] [location=comp... gi\|194469412, gi... - gi\|194469412\|ref\|ZP_03075396.1\| protein-export chaperone SecB [Salmonella enterica subsp. enterica s... SECB_SALCH - Protein-export protein secB OS=Salmonella choleraesuis GN=secB PE=3 SV=1 gi\|168235305, gi... - gi\|197291403\|gb\|EDY30755.1\| protein-export chaperone SecB [Salmonella enterica subsp. enterica serov... gi\|168241879, gi... - gi\|205339070\|gb\|EDZ25834.1\| protein-export chaperone SecB [Salmonella enterica subsp. enterica serov... gi\|168260545, gi... - gi\|205350292\|gb\|EDZ36923.1\| protein-export chaperone SecB [Salmonella enterica subsp. enterica serov... gi\|168464992, gi... - gi\|195632116\|gb\|EDX50600.1\| protein-export chaperone SecB [Salmonella enterica subsp. enterica serov...	254.0	[0..1]	[155..1]
SECB_ECOUT - Protein-export protein SecB OS=Escherichia coli (strain UTI89 / UPEC) GN=secB PE=3 SV=2 SECB_ECOLC - Protein-export protein SecB OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=secB PE=3 ... SECB_ECOK1 - Protein-export protein SecB OS=Escherichia coli O1:K1 / APEC GN=secB PE=3 SV=2 SECB_ECO45 - Protein-export protein SecB OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=secB PE=3 SV=1 SECB_ECO81 - Protein-export protein SecB OS=Escherichia coli O81 (strain ED1a) GN=secB PE=3 SV=1 SECB_ECOSE - Protein-export protein SecB OS=Escherichia coli (strain SE11) GN=secB PE=3 SV=1 SECB_ECO27 - Protein-export protein SecB OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=secB PE=3 SV=1 gi\|124499157, gi... - gi\|124530516\|ref\|ZP_01701143.1\| protein-export protein SecB [Escherichia coli B], gi\|124499157\|gb\|EA... SECB_ECOL5 - Protein-export protein SecB OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=secB PE=3 SV=1 gi\|170124363, gi... - gi\|170766925\|ref\|ZP_02901378.1\| protein-export chaperone SecB [Escherichia albertii TW07627], gi\|170... gi\|194420748, gi... - gi\|83571402\|ref\|ZP_00922842.1\| COG1952: Preprotein translocase subunit SecB [Shigella dysenteriae 10... gi\|190909305, gi... - gi\|75242605\|ref\|ZP_00726349.1\| COG1952: Preprotein translocase subunit SecB [Escherichia coli F11], ... sp\|B7ULG5\|SECB_ECO27 - Protein-export protein secB OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=secB PE=3 SV=1 gi\|188493596, gi... - gi\|75514322\|ref\|ZP_00736630.1\| COG1952: Preprotein translocase subunit SecB [Escherichia coli 53638]... SECB_SHIDS - Protein-export protein SecB OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=secB PE=3 SV=1	253.0	[0..1]	[155..1]
SECB_SHISS - Protein-export protein SecB OS=Shigella sonnei (strain Ss046) GN=secB PE=3 SV=1	253.0	[0..1]	[155..1]
gi\|40889477, gi\|... - gi\|40889480\|pdb\|1QYN\|D Chain D, Crystal Structure Of Secb From Escherichia Coli, gi\|40889479\|pdb\|1QY...	249.0	[0..1]	[153..1]
gi\|77977372 - gi\|77977372\|ref\|ZP_00832822.1\| COG1952: Preprotein translocase subunit SecB [Yersinia intermedia ATC...	244.0	[0..1]	[155..1]
gi\|77958477 - gi\|77958477\|ref\|ZP_00822510.1\| COG1952: Preprotein translocase subunit SecB [Yersinia bercovieri ATC... gi\|77961959 - gi\|77961959\|ref\|ZP_00825786.1\| COG1952: Preprotein translocase subunit SecB [Yersinia mollaretii ATC... SECB_YERE8 - Protein-export protein SecB OS=Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 ...	244.0	[0..1]	[155..1]
SECB_PECAS - Protein-export protein SecB OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) GN=secB... SECB_ERWCT - Protein-export protein secB OS=Erwinia carotovora subsp. atroseptica GN=secB PE=3 SV=1	242.0	[0..1]	[155..1]
gi\|77972954 - gi\|77972954\|ref\|ZP_00828508.1\| COG1952: Preprotein translocase subunit SecB [Yersinia frederiksenii ...	241.0	[0..1]	[155..1]

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Predicted Domain #1

Region A:
Residues: [1-155]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEQNNTEMT FQIQRIYTKD ISFEAPNAPH VFQKDWQPEV KLDLDTASSQ LADDVYEVVL  60
   61 RVTVTASLGE ETAFLCEVQQ GGIFSIAGIE GTQMAHCLGA YCPNILFPYA RECITSMVSR 120
  121 GTFPQLNLAP VNFDALFMNY LQQQAGEGTE EHQDA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.69897
Match:	1qynA
Description:	Crystal Structure of SecB from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein transporter activity	6.35026304666251	bayes_pls_golite062009
binding	2.83315924084513	bayes_pls_golite062009
unfolded protein binding	2.16552514584831	bayes_pls_golite062009
protein binding	1.68053363123835	bayes_pls_golite062009
transporter activity	1.14731421693772	bayes_pls_golite062009
substrate-specific transporter activity	0.747128915267314	bayes_pls_golite062009
transmembrane transporter activity	0.658797982643155	bayes_pls_golite062009
protein transmembrane transporter activity	0.1698588415231	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.123631482979072	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: