YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|39654823
Organism:	Homo sapiens
Length:	262 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39654823.

Description	E-value	Query Range	Subject Range
gi\|89268211, gi\|... - gi\|89268211\|emb\|CAJ82567.1\| Novel protein containing CRAL/TRIO domain [Xenopus tropicalis], gi\|62859...	235.0	[0..2]	[254..42]
TTPAL - tocopherol (alpha) transfer protein-like	232.0	[0..2]	[261..45]
gi\|55725059 - gi\|55725059\|emb\|CAH89397.1\| hypothetical protein [Pongo abelii] TTPAL_PONAB - Alpha-tocopherol transfer protein-like OS=Pongo abelii GN=TTPAL PE=2 SV=1	232.0	[0..2]	[261..45]
gi\|114682122, gi... - gi\|114682124\|ref\|XP_001152483.1\| PREDICTED: similar to chromosome 20 open reading frame 121 isoform ...	232.0	[0..2]	[261..45]
gi\|109091885, gi... - gi\|109091887\|ref\|XP_001110534.1\| PREDICTED: hypothetical protein LOC79183 isoform 3 [Macaca mulatta]...	232.0	[0..2]	[261..45]
gi\|71894993, gi\|... - gi\|71894993\|ref\|NP_001026025.1\| chromosome 20 open reading frame 121 [Gallus gallus], gi\|60099197\|em...	231.0	[0..2]	[257..43]
gi\|57104224 - gi\|57104224\|ref\|XP_534426.1\| PREDICTED: similar to Protein C20orf121 homolog [Canis familiaris]	231.0	[0..2]	[257..45]
TTPAL_MOUSE - Alpha-tocopherol transfer protein-like OS=Mus musculus GN=Ttpal PE=1 SV=3	230.0	[0..2]	[261..46]
gi\|157818193, gi... - gi\|34860761\|ref\|XP_230830.2\| PREDICTED: similar to Protein C20orf121 homolog [Rattus norvegicus], gi...	230.0	[0..2]	[257..46]

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Predicted Domain #1

Region A:
Residues: [1-262]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSHMSPLLQP GLAALRRRAR EAGVPLAPLP LTDSFLLRFL RARDFDLDLA WRLLKNYYKW  60
   61 RAECPEISAD LHPRSIIGLL KAGYHGVLRS RDPTGSKVLI YRIAHWDPKV FTAYDVFRVS 120
  121 LITSELIVQE VETQRNGIKA IFDLEGWQFS HAFQITPSVA KKIAAVLTDS FPLKVRGIHL 180
  181 INEPVIFHAV FSXIKPFLTE KIKERIHXHG NNYKQSLLQH FPDILPLEYG GEEFSXEDIC 240
  241 QEWTNFIXKS EDYLSSISES IQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.09691
Match:	1r5lA
Description:	Crystal Structure of Human Alpha-Tocopherol Transfer Protein Bound to its Ligand
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
vitamin E binding	7.60287756659728	bayes_pls_golite062009
retinoid binding	2.55932836548393	bayes_pls_golite062009
isoprenoid binding	2.50048436206147	bayes_pls_golite062009
vitamin binding	1.77103204070558	bayes_pls_golite062009
binding	1.64101337554248	bayes_pls_golite062009
retinal binding	1.32654212303069	bayes_pls_golite062009
transporter activity	1.00447017621654	bayes_pls_golite062009
substrate-specific transporter activity	0.658164745879483	bayes_pls_golite062009
protein binding	0.408110742195811	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: