YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|167469926
Organism:	Yersinia pestis FV-1
Length:	323 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|167469926.

Description	E-value	Query Range	Subject Range
gi\|21958288, gi\|... - gi\|22125402\|ref\|NP_668825.1\| glucokinase [Yersinia pestis KIM], gi\|21958288\|gb\|AAM85076.1\|AE013753_7...	4.0E-62	[1..323]	[2..324]
GLK_SHIDS - Glucokinase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=glk PE=3 SV=1	3.0E-60	[1..321]	[1..321]
GLK_ECOLC - Glucokinase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=glk PE=3 SV=1 gi\|208741993, gi... - gi\|208821870\|ref\|ZP_03262190.1\| glucokinase [Escherichia coli O157:H7 str. EC4042], gi\|208741993\|gb\|... gi\|208733196, gi... - gi\|208811919\|ref\|ZP_03253248.1\| glucokinase [Escherichia coli O157:H7 str. EC4045], gi\|208733196\|gb\|... GLK_ECOSE - Glucokinase OS=Escherichia coli (strain SE11) GN=glk PE=3 SV=1 GLK_ECO5E - Glucokinase OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=glk PE=3 SV=1 GLK_ECO8A - Glucokinase OS=Escherichia coli O8 (strain IAI1) GN=glk PE=3 SV=1 gi\|217320106, gi... - gi\|217327739\|ref\|ZP_03443822.1\| glucokinase [Escherichia coli O157:H7 str. TW14588], gi\|217320106\|gb... GLK_ECOLU - Glucokinase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=glk PE=3 SV=1 GLK_ECOBW - Glucokinase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=glk PE=3 SV=1 GLK_ECO55 - Glucokinase OS=Escherichia coli (strain 55989 / EAEC) GN=glk PE=3 SV=1 gi\|242378005, gi... - gi\|251785732\|ref\|YP_003000036.1\| hypothetical protein B21_02259 [Escherichia coli BL21], gi\|24237800... gi\|253772703, gi... - gi\|254289142\|ref\|YP_003054890.1\| glucokinase [Escherichia coli BL21(DE3)], gi\|253978449\|gb\|ACT44119.... gi\|254162381, gi... - gi\|254162381\|ref\|YP_003045489.1\| glucokinase [Escherichia coli B str. REL606], gi\|253974282\|gb\|ACT39... gi\|254794350, gi... - gi\|254794350\|ref\|YP_003079187.1\| glucokinase [Escherichia coli O157:H7 str. TW14359], gi\|254593750\|g... GLK_ECOLI - Glucokinase (EC 2.7.1.2) (Glucose kinase) - Escherichia coli gi\|188495762, gi... - gi\|75515734\|ref\|ZP_00737869.1\| COG0837: Glucokinase [Escherichia coli 53638], gi\|188495762\|ref\|ZP_03... gi\|193062455, gi... - gi\|75259830\|ref\|ZP_00731132.1\| COG0837: Glucokinase [Escherichia coli E22], gi\|193062455\|ref\|ZP_0304... gi\|193069752, gi... - gi\|75235576\|ref\|ZP_00719767.1\| COG0837: Glucokinase [Escherichia coli E110019], gi\|193069752\|ref\|ZP_... gi\|75231324, gi\|... - gi\|75231324\|ref\|ZP_00717712.1\| COG0837: Glucokinase [Escherichia coli B7A], gi\|191165572\|ref\|ZP_0302... gi\|194428625, gi... - gi\|75210178\|ref\|ZP_00710350.1\| COG0837: Glucokinase [Escherichia coli B171], gi\|194428625\|ref\|ZP_030... GLK_ECOHS - Glucokinase OS=Escherichia coli O9:H4 (strain HS) GN=glk PE=3 SV=1 GLK_ECO24 - Glucokinase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=glk PE=3 SV=1 gi\|194440108, gi... - gi\|83584567\|ref\|ZP_00923239.1\| COG0837: Glucokinase [Escherichia coli 101-1], gi\|194440108\|ref\|ZP_03... gi\|89109208, gi\|... - gi\|89109208\|ref\|AP_002988.1\| glucokinase [Escherichia coli str. K-12 substr. W3110], gi\|1799799\|dbj\|... gi\|13362738, gi\|... - gi\|15832522\|ref\|NP_311295.1\| glucokinase [Escherichia coli O157:H7 str. Sakai], gi\|13362738\|dbj\|BAB3... gi\|168772773, gi... - gi\|187771179\|gb\|EDU35023.1\| glucokinase [Escherichia coli O157:H7 str. EC4196], gi\|168772773\|ref\|ZP_... gi\|189360233, gi... - gi\|189360233\|gb\|EDU78652.1\| glucokinase [Escherichia coli O157:H7 str. EC4486], gi\|168770962\|ref\|ZP_... gi\|189372971, gi... - gi\|189372971\|gb\|EDU91387.1\| glucokinase [Escherichia coli O157:H7 str. EC869], gi\|168787306\|ref\|ZP_0... gi\|124502005, gi... - gi\|124526534\|ref\|ZP_01698487.1\| glucokinase [Escherichia coli B], gi\|124502005\|gb\|EAY49466.1\| glucok... gi\|189002152, gi... - gi\|189002152\|gb\|EDU71138.1\| glucokinase [Escherichia coli O157:H7 str. EC4076], gi\|168780354\|ref\|ZP_... GLK_ECO57 - Glucokinase OS=Escherichia coli O157:H7 GN=glk PE=1 SV=1 GLK_ECODH - Glucokinase OS=Escherichia coli (strain K12 / DH10B) GN=glk PE=3 SV=1 EG12957 - glucokinase / Glucokinase gi\|168800729, gi... - gi\|189377042\|gb\|EDU95458.1\| glucokinase [Escherichia coli O157:H7 str. EC508], gi\|168800729\|ref\|ZP_0... gi\|12516765, gi\|... - gi\|15802930\|ref\|NP_288958.1\| glucokinase [Escherichia coli O157:H7 EDL933], gi\|12516765\|gb\|AAG57514.... gi\|208728583, gi... - gi\|208808782\|ref\|ZP_03251119.1\| glucokinase [Escherichia coli O157:H7 str. EC4206], gi\|208728583\|gb\|... EG12957 - glucokinase / Glucokinase gi\|195938742 - gi\|195938742\|ref\|ZP_03084124.1\| glucokinase [Escherichia coli O157:H7 str. EC4024] gi\|168748347, gi... - gi\|188017239\|gb\|EDU55361.1\| glucokinase [Escherichia coli O157:H7 str. EC4113], gi\|168748347\|ref\|ZP_... gi\|168763569, gi... - gi\|189366347\|gb\|EDU84763.1\| glucokinase [Escherichia coli O157:H7 str. EC4501], gi\|168763569\|ref\|ZP_... gi\|168757438, gi... - gi\|189355621\|gb\|EDU74040.1\| glucokinase [Escherichia coli O157:H7 str. EC4401], gi\|168757438\|ref\|ZP_...	4.0E-60	[1..321]	[1..321]
gi\|227835789, gi... - gi\|227887439\|ref\|ZP_04005244.1\| glucokinase [Escherichia coli 83972], gi\|227835789\|gb\|EEJ46255.1\| gl... sp\|B7UG97\|GLK_ECO27 - Glucokinase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=glk PE=3 SV=1 gi\|226901282, gi... - gi\|237704916\|ref\|ZP_04535397.1\| glucokinase [Escherichia sp. 3_2_53FAA], gi\|226901282\|gb\|EEH87541.1\|... GLK_ECOK1 - Glucokinase OS=Escherichia coli O1:K1 / APEC GN=glk PE=3 SV=1 GLK_ECOL6 - Glucokinase OS=Escherichia coli O6 GN=glk PE=3 SV=1 GLK_ECO45 - Glucokinase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=glk PE=3 SV=1 GLK_ECOL6 - Glucokinase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=glk PE=3 SV=1 GLK_ECO27 - Glucokinase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=glk PE=3 SV=1 GLK_ECOUT - Glucokinase OS=Escherichia coli (strain UTI89 / UPEC) GN=glk PE=3 SV=1 GLK_ECOL5 - Glucokinase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=glk PE=3 SV=1 GLK_ECO81 - Glucokinase OS=Escherichia coli O81 (strain ED1a) GN=glk PE=3 SV=1 gi\|75237954, gi\|... - gi\|75237954\|ref\|ZP_00721961.1\| COG0837: Glucokinase [Escherichia coli F11], gi\|191173778\|ref\|ZP_0303...	7.0E-60	[1..321]	[1..321]
gi\|77979147 - gi\|77979147\|ref\|ZP_00834568.1\| COG0837: Glucokinase [Yersinia intermedia ATCC 29909]	8.0E-60	[1..321]	[1..321]
GLK_SHIF8 - Glucokinase OS=Shigella flexneri serotype 5b (strain 8401) GN=glk PE=3 SV=1 gi\|24052821, gi\|... - gi\|24113745\|ref\|NP_708255.1\| glucokinase [Shigella flexneri 2a str. 301], gi\|24052821\|gb\|AAN43962.1\|... gi\|30042047, gi\|... - gi\|30063792\|ref\|NP_837963.1\| glucokinase [Shigella flexneri 2a str. 2457T], gi\|30042047\|gb\|AAP17773.... GLK_SHIFL - Glucokinase OS=Shigella flexneri GN=glk PE=3 SV=1	8.0E-60	[1..321]	[1..321]
GLK_SHISS - Glucokinase OS=Shigella sonnei (strain Ss046) GN=glk PE=3 SV=1	8.0E-60	[1..321]	[1..321]
gi\|736416 - gi\|736416\|gb\|AAA64506.1\| glucokinase [Escherichia coli]	9.0E-60	[1..321]	[1..321]
gi\|238789993, gi... - gi\|77975605\|ref\|ZP_00831140.1\| COG0837: Glucokinase [Yersinia frederiksenii ATCC 33641], gi\|23878999...	9.0E-60	[1..321]	[1..321]
gi\|83570011, gi\|... - gi\|83570011\|ref\|ZP_00921458.1\| COG0837: Glucokinase [Shigella dysenteriae 1012], gi\|194432899\|ref\|ZP...	1.0E-59	[1..321]	[1..321]

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Predicted Domain #1

Region A:
Residues: [1-323]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTYALVGDV GGTNARLALC AVATGEILQA KTYSGLEYES LEDVIKQYLS EHQAKVTDAC  60
   61 IAIACPITGD WVAMTNHTWA FSIAAMQQNL GLDHLEVIND FTAVSMAIPV LPAQDVLQFG 120
  121 GTQPQPGKPV AVYGAGTGLG VAHLVNVDRR WISLAGEGGH VDFAPNSEEE DQILAVLRQE 180
  181 LGHVSAERVL SGPGLVNLYR AIVISDARLP EKLAPKDITA RALADSCTDC RRALSLFCVI 240
  241 MGRFGGNLAL NLSTFGGVYI AGGIVPRFME FFKASGFRAA FEDKGRFKDF LQDIPVYMIT 300
  301 HPQPGLLGAG AYLRQKLGYE LSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.522879
Match:	1q18A
Description:	Crystal structure of E.coli glucokinase (Glk)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbohydrate kinase activity	0.7849166795124	bayes_pls_golite062009
catalytic activity	0.666924658593345	bayes_pls_golite062009
hexokinase activity	0.32024736915472	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: