YRC Public Data Repository - Protein Structure Prediction

Protein:	TYPA_ECO27
Organism:	Escherichia coli O127:H6 str. E2348/69
Length:	607 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TYPA_ECO27.

Description	E-value	Query Range	Subject Range
gi\|187429977, gi... - gi\|75176744\|ref\|ZP_00696872.1\| COG1217: Predicted membrane GTPase involved in stress response [Shige... gi\|82546215, gi\|... - gi\|82546215\|ref\|YP_410162.1\| GTP-binding protein [Shigella boydii Sb227], gi\|81247626\|gb\|ABB68334.1\|...	626.0	[0..1]	[606..1]
gi\|30043100, gi\|... - gi\|30064840\|ref\|NP_839011.1\| GTP-binding protein [Shigella flexneri 2a str. 2457T], gi\|30043100\|gb\|A...	626.0	[0..1]	[607..1]
gi\|83586280, gi\|... - gi\|83586280\|ref\|ZP_00924916.1\| COG1217: Predicted membrane GTPase involved in stress response [Esche...	626.0	[0..1]	[606..1]
gi\|194435177, gi... - gi\|83568945\|ref\|ZP_00920411.1\| COG1217: Predicted membrane GTPase involved in stress response [Shige...	626.0	[0..1]	[607..1]
gi\|127514481, gi... - gi\|78365939\|ref\|ZP_00836222.1\| Small GTP-binding protein domain:GTP-binding protein TypA [Shewanella...	624.0	[0..1]	[606..1]
gi\|68517054, gi\|... - gi\|68545186\|ref\|ZP_00584737.1\| Small GTP-binding protein domain:GTP-binding protein TypA [Shewanella...	623.0	[0..1]	[602..1]
gi\|46143322 - gi\|46143322\|ref\|ZP_00135497.2\| COG1217: Predicted membrane GTPase involved in stress response [Actin...	621.0	[0..2]	[602..6]
gi\|153094722, gi... - gi\|254363057\|ref\|ZP_04979116.1\| possible GTP-binding protein TypA [Mannheimia haemolytica PHL213], g... gi\|110735363 - gi\|110735363\|gb\|ABG89252.1\| putative GTP-binding factor [Mannheimia haemolytica]	620.0	[0..2]	[602..6]
gi\|205348302, gi... - gi\|205348302\|gb\|EDZ34933.1\| GTP-binding protein TypA [Salmonella enterica subsp. enterica serovar Ha... gi\|194443181, gi... - gi\|194443181\|ref\|YP_002043230.1\| GTP-binding protein TypA [Salmonella enterica subsp. enterica serov... gi\|194451908, gi... - gi\|194451908\|ref\|YP_002048011.1\| GTP-binding protein [Salmonella enterica subsp. enterica serovar He... gi\|194711909, gi... - gi\|194736407\|ref\|YP_002116928.1\| GTP-binding protein TypA [Salmonella enterica subsp. enterica serov... gi\|168237624, gi... - gi\|197289403\|gb\|EDY28768.1\| GTP-binding protein TypA [Salmonella enterica subsp. enterica serovar Sc... gi\|205336867, gi... - gi\|205336867\|gb\|EDZ23631.1\| GTP-binding protein TypA [Salmonella enterica subsp. enterica serovar He... gi\|16762424 - gi\|16762424\|ref\|NP_458041.1\| GTP-binding protein [Salmonella enterica subsp. enterica serovar Typhi ... gi\|16504728, gi\|... - pir\|\|AH0949 GTP-binding protein [imported] - Salmonella enterica subsp. enterica serovar Typhi (stra... gi\|11024578 - gi\|11024578\|emb\|CAC14268.1\| BipA GTPase [Salmonella enterica] gi\|56415855, gi\|... - gi\|56415855\|ref\|YP_152930.1\| GTP-binding protein [Salmonella enterica subsp. enterica serovar Paraty... gi\|213426416 - gi\|213426416\|ref\|ZP_03359166.1\| GTP-binding protein [Salmonella enterica subsp. enterica serovar Typ... gi\|213616219 - gi\|213616219\|ref\|ZP_03372045.1\| GTP-binding protein [Salmonella enterica subsp. enterica serovar Typ... gi\|213852016 - gi\|213852016\|ref\|ZP_03381548.1\| GTP-binding protein [Salmonella enterica subsp. enterica serovar Typ... gi\|214002898 - gi\|214002898\|ref\|ZP_03413633.1\| GTP-binding protein [Salmonella enterica subsp. enterica serovar Typ... gi\|205354409, gi... - gi\|205354409\|ref\|YP_002228210.1\| GTP-binding protein [Salmonella enterica subsp. enterica serovar Ga... gi\|207859200, gi... - gi\|207859200\|ref\|YP_002245851.1\| GTP-binding protein [Salmonella enterica subsp. enterica serovar En... gi\|213027497 - gi\|213027497\|ref\|ZP_03341944.1\| GTP-binding protein [Salmonella enterica subsp. enterica serovar Typ... gi\|213162860 - gi\|213162860\|ref\|ZP_03348570.1\| GTP-binding protein [Salmonella enterica subsp. enterica serovar Typ... gi\|197096262, gi... - gi\|197364785\|ref\|YP_002144422.1\| GTP-binding protein [Salmonella enterica subsp. enterica serovar Pa... gi\|198242119, gi... - gi\|198242119\|ref\|YP_002217929.1\| GTP-binding protein TypA [Salmonella enterica subsp. enterica serov... gi\|200388210, gi... - gi\|200388210\|ref\|ZP_03214822.1\| GTP-binding protein TypA [Salmonella enterica subsp. enterica serova... gi\|204930278, gi... - gi\|204930278\|ref\|ZP_03221255.1\| GTP-binding protein TypA [Salmonella enterica subsp. enterica serova...	620.0	[0..1]	[607..1]
gi\|113890647, gi... - gi\|78691128\|ref\|ZP_00855757.1\| Small GTP-binding protein domain:GTP-binding protein TypA [Shewanella... gi\|82495546, gi\|... - gi\|82495546\|ref\|ZP_00881121.1\| Small GTP-binding protein domain:GTP-binding protein TypA [Shewanella...	620.0	[0..1]	[602..1]

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Predicted Domain #1

Region A:
Residues: [1-607]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIEKLRNIAI IAHVDHGKTT LVDKLLQQSG TFDSRAETQE RVMDSNDLEK ERGITILAKN  60
   61 TAIKWNDYRI NIVDTPGHAD FGGEVERVMS MVDSVLLVVD AFDGPMPQTR FVTKKAFAYG 120
  121 LKPIVVINKV DRPGARPDWV VDQVFDLFVN LDATDEQLDF PIVYASALNG IAGLDHEDMA 180
  181 EDMTPLYQAI VDHVPAPDVD LDGPFQMQIS QLDYNSYVGV IGIGRIKRGK VKPNQQVTII 240
  241 DSEGKTRNAK VGKVLGHLGL ERIETDLAEA GDIVAITGLG ELNISDTVCD TQNVEALPAL 300
  301 SVDEPTVSMF FCVNTSPFCG KEGKFVTSRQ ILDRLNKELV HNVALRVEET EDADAFRVSG 360
  361 RGELHLSVLI ENMRREGFEL AVSRPKVIFR EIDGRKQEPY ENVTLDVEEQ HQGSVMQALG 420
  421 ERKGDLKNMN PDGKGRVRLD YVIPSRGLIG FRSEFMTMTS GTGLLYSTFS HYDDVRPGEV 480
  481 GQRQNGVLIS NGQGKAVAFA LFGLQDRGKL FLGHGAEVYE GQIIGIHSRS NDLTVNCLTG 540
  541 KKLTNMRASG TDEAVVLVPP IRMTLEQALE FIDDDELVEV TPTSIRIRKR HLTENDRRRA 600
  601 NRAPKDD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	103.0
Match:	1fnmA
Description:	Elongation factor G (EF-G), domain II; Elongation factor G (EF-G), N-terminal (G) domain; Elongation factor G (EF-G), domain IV; Elongation factor G (EF-G)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural constituent of ribosome	1.36336810177757	bayes_pls_golite062009
catalytic activity	1.24889475603062	bayes_pls_golite062009
structural molecule activity	1.08228539493269	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: