YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|39654123
Organism:	Homo sapiens
Length:	141 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39654123.

Description	E-value	Query Range	Subject Range
gi\|61368148, gi\|... - gi\|61368148\|gb\|AAX43114.1\| neutrophil cytosolic factor 1 [synthetic construct], gi\|54695778\|gb\|AAV38...	141.0	[0..2]	[140..2]
gi\|62897995, gi\|... - gi\|62897995\|dbj\|BAD96937.1\| neutrophil cytosolic factor 1 variant [Homo sapiens], gi\|12803939\|gb\|AAH... gi\|123999871, gi... - gi\|123999871\|gb\|ABM87444.1\| neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal...	141.0	[0..2]	[140..2]
NCF1 - neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) gi\|114614035 - gi\|114614035\|ref\|XP_001152639.1\| PREDICTED: neutrophil cytosolic factor 1 isoform 4 [Pan troglodytes...	141.0	[0..2]	[140..2]
gi\|73957728 - gi\|73957728\|ref\|XP_849574.1\| PREDICTED: similar to Neutrophil cytosol factor 1 (NCF-1) (Neutrophil N...	141.0	[0..2]	[140..2]
gi\|15987063 - gi\|15987063\|gb\|AAL11888.1\|AF411138_1 NADPH oxidase cytosolic protein p47phox [Bison bison]	140.0	[0..2]	[140..2]
NCF1_BOVIN - Neutrophil cytosol factor 1 OS=Bos taurus GN=NCF1 PE=2 SV=1	139.0	[0..2]	[140..2]
gi\|109066344 - gi\|109066344\|ref\|XP_001084055.1\| PREDICTED: neutrophil cytosolic factor 1 [Macaca mulatta]	139.0	[0..2]	[140..2]
gi\|8439513 - gi\|8439513\|dbj\|BAA96544.1\| p47-phox [Tursiops truncatus]	137.0	[0..2]	[140..2]

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Predicted Domain #1

Region A:
Residues: [1-141]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 XGDTFIRHIA LLGFEKRFVP SQHYVYXFLV KWQDLSEKVV YRRFTEIYEF HKTLKEXFPI  60
   61 EAGAINPENR IIPHLPAPKW FDGQRAAENR QGTLTEYCST LXSLPTKISR CPHLLDFFKV 120
  121 RPDDLKLPTD NQTKKPETYL X

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.0
Match:	1kq6A
Description:	p47phox PX domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
superoxide-generating NADPH oxidase activity	8.63830455853479	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH, with oxygen as acceptor	3.2768274009426	bayes_pls_golite062009
binding	2.40415151173972	bayes_pls_golite062009
protein binding	1.70694796663015	bayes_pls_golite062009
lipid binding	0.277020803861689	bayes_pls_golite062009
catalytic activity	0.114035192741535	bayes_pls_golite062009
phospholipid binding	0.00138455412568295	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: