YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|167635112, gi...
Organism:	Bacillus anthracis str. A0442
Length:	247 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|167635112, gi....

Description	E-value	Query Range	Subject Range
gi\|152973939, gi... - gi\|89203255\|ref\|ZP_01181941.1\| RNA methyltransferase TrmH, group 3 [Bacillus cereus subsp. cytotoxis...	7.0E-71	[1..247]	[1..247]
gi\|25316695 - pir\|\|A83664 tRNA/rRNA methyltransferase BH0113 [imported] - Bacillus halodurans (strain C-125) gi\|15612676, gi\|... - gi\|15612676\|ref\|NP_240979.1\| tRNA/rRNA methyltransferase [Bacillus halodurans C-125], gi\|10172725\|db...	2.0E-70	[1..247]	[1..248]
gi\|206732774, gi... - gi\|206972200\|ref\|ZP_03233147.1\| RNA methyltransferase, TrmH family, group 3 [Bacillus cereus AH1134]... gi\|218160251, gi... - gi\|218232294\|ref\|YP_002364941.1\| RNA methyltransferase, TrmH family, group 3 [Bacillus cereus B4264]... gi\|30018362, gi\|... - gi\|30018362\|ref\|NP_829993.1\| 23S rRNA methyltransferase [Bacillus cereus ATCC 14579], gi\|29893902\|gb...	4.0E-70	[1..247]	[1..247]
gi\|89208519, gi\|... - gi\|89208519\|ref\|ZP_01187021.1\| RNA methyltransferase TrmH, group 3 [Bacillus weihenstephanensis KBAB...	1.0E-69	[1..247]	[1..247]
gi\|52001802, gi\|... - gi\|52783952\|ref\|YP_089781.1\| YacO [Bacillus licheniformis ATCC 14580], gi\|52346454\|gb\|AAU39088.1\| Ya...	6.0E-68	[4..247]	[6..249]
gi\|23097556, gi\|... - gi\|23097556\|ref\|NP_691022.1\| tRNA:rRNA methyltransferase [Oceanobacillus iheyensis HTE831], gi\|22775...	9.0E-68	[1..246]	[1..246]
gi\|221312229 - gi\|221312229\|ref\|ZP_03594034.1\| hypothetical protein BsubsN3_00495 [Bacillus subtilis subsp. subtili... gi\|221317163 - gi\|221317163\|ref\|ZP_03598457.1\| hypothetical protein BsubsJ_00500 [Bacillus subtilis subsp. subtilis... gi\|221321426 - gi\|221321426\|ref\|ZP_03602720.1\| hypothetical protein BsubsS_00500 [Bacillus subtilis subsp. subtilis... YACO_BACSU - Putative TrmH family tRNA/rRNA methyltransferase YacO OS=Bacillus subtilis GN=yacO PE=3 SV=2 YACO_BACSU - Putative TrmH family tRNA/rRNA methyltransferase YacO OS=Bacillus subtilis (strain 168) GN=yacO PE=3...	2.0E-67	[4..247]	[6..249]
gi\|77954715, gi\|... - gi\|77954715\|ref\|ZP_00819103.1\| RNA methyltransferase TrmH, group 3 [Marinobacter aquaeolei VT8], gi\|...	6.0E-67	[1..242]	[1..243]
gi\|56418622, gi\|... - gi\|56418622\|ref\|YP_145940.1\| tRNA/rRNA methyltransferase [Geobacillus kaustophilus HTA426], gi\|56378...	1.0E-66	[4..247]	[2..245]
gi\|48859457, gi\|... - gi\|67875040\|ref\|ZP_00504559.1\| RNA methyltransferase TrmH, group 3 [Clostridium thermocellum ATCC 27... gi\|196198671, gi... - gi\|196251913\|ref\|ZP_03150578.1\| RNA methyltransferase, TrmH family, group 3 [Clostridium thermocellu...	2.0E-66	[4..244]	[36..277]

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Predicted Domain #1

Region A:
Residues: [1-247]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSEYIIGRN PVIEALRSGR DINKIWIAEG AAKGQVQIVL ALAKENKIIL QHAPKKKLDQ  60
   61 LVEGNHQGVI AQVAAYQYAE LEDLFKVAEK RNEDPFFLIL DEIEDPHNLG SIMRTADATG 120
  121 AHGIIIPKRR AVGLTASVAK ASTGAIEYIP VARVTNLSRT IDELKERGLW IAGTDAKGKT 180
  181 DYRNLDGKMP IGLVIGSEGK GMSRIIGEKC DFLITLPMVG KVTSLNASVA ASLLMYEVYR 240
  241 KRNEIGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.0
Match:	1gz0A
Description:	RlmB, C-terminal domain; RlmB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA methyltransferase activity	4.23455016472464	bayes_pls_golite062009
methyltransferase activity	3.59960278169345	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.51722801996622	bayes_pls_golite062009
rRNA methyltransferase activity	3.14976989427746	bayes_pls_golite062009
tRNA methyltransferase activity	2.33123191403389	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.23755555119187	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	2.14623472760939	bayes_pls_golite062009
transferase activity	1.63934797352054	bayes_pls_golite062009
structural constituent of ribosome	1.0137045454994	bayes_pls_golite062009
catalytic activity	0.797300463760338	bayes_pls_golite062009
N-methyltransferase activity	0.736216022000293	bayes_pls_golite062009
structural molecule activity	0.694233763389628	bayes_pls_golite062009
binding	0.650146274744039	bayes_pls_golite062009
nucleic acid binding	0.404179021204849	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.319046095835882	bayes_pls_golite062009
	0.16936231012632	bayes_pls_golite062009
snoRNA binding	0.155192244522672	bayes_pls_golite062009
protein binding	0.031057919963412	bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity	6.26422903788337E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: