YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|165919867, gi...
Organism:	Yersinia pestis biovar Orientalis str. F1991016
Length:	277 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|165919867, gi....

Description	E-value	Query Range	Subject Range
gi\|170025950, gi... - gi\|170025950\|ref\|YP_001722455.1\| dihydropteroate synthase [Yersinia pseudotuberculosis YPIII], gi\|16... gi\|186893836, gi... - gi\|186893836\|ref\|YP_001870948.1\| dihydropteroate synthase [Yersinia pseudotuberculosis PB1/+], gi\|18... gi\|51588109, gi\|... - gi\|51594827\|ref\|YP_069018.1\| dihydropteroate synthase [Yersinia pseudotuberculosis IP 32953], gi\|515... Q66F65\|Q66F65_YERPS - Dihydropteroate synthase - Yersinia pseudotuberculosis gi\|117675036, gi... - gi\|77631472\|ref\|ZP_00794058.1\| COG0294: Dihydropteroate synthase and related enzymes [Yersinia pseud...	2.0E-99	[1..277]	[1..277]
gi\|77634743, gi\|... - gi\|77634743\|ref\|ZP_00796837.1\| COG0294: Dihydropteroate synthase and related enzymes [Yersinia pesti...	2.0E-99	[1..277]	[1..277]
gi\|26110188, gi\|... - gi\|26249760\|ref\|NP_755800.1\| Dihydropteroate synthase [Escherichia coli CFT073], gi\|26110188\|gb\|AAN8...	5.0E-97	[1..276]	[23..298]
gi\|237706072, gi... - gi\|237706072\|ref\|ZP_04536553.1\| 7,8-dihydropteroate synthase [Escherichia sp. 3_2_53FAA], gi\|2268991... gi\|91074172, gi\|... - gi\|91212598\|ref\|YP_542584.1\| 7,8-dihydropteroate synthase [Escherichia coli UTI89], gi\|91074172\|gb\|A...	7.0E-97	[1..276]	[23..298]
gi\|74313714, gi\|... - gi\|74313714\|ref\|YP_312133.1\| 7,8-dihydropteroate synthase [Shigella sonnei Ss046], gi\|73857191\|gb\|AA...	9.0E-97	[1..276]	[16..291]
gi\|162138365 - gi\|162138365\|ref\|YP_542584.2\| dihydropteroate synthase [Escherichia coli UTI89] gi\|218367016, gi... - gi\|218560247\|ref\|YP_002393160.1\| dihydropteroate synthase [Escherichia coli S88], gi\|218367016\|emb\|C... gi\|117625471, gi... - gi\|117625471\|ref\|YP_858794.1\| dihydropteroate synthase [Escherichia coli APEC O1], gi\|115514595\|gb\|A...	1.0E-96	[1..276]	[1..276]
gi\|81246996, gi\|... - gi\|82545585\|ref\|YP_409532.1\| 7,8-dihydropteroate synthase [Shigella boydii Sb227], gi\|81246996\|gb\|AB...	1.0E-96	[1..276]	[16..291]
EG50011 - 7,8-dihydropteroate synthase / Dihydropteroate synthase DHPS_SHIFL - Dihydropteroate synthase OS=Shigella flexneri GN=folP PE=3 SV=1 gi\|161367517 - gi\|161367517\|ref\|NP_289751.2\| dihydropteroate synthase [Escherichia coli O157:H7 EDL933] gi\|38704146 - gi\|38704146\|ref\|NP_312083.2\| 7,8-dihydropteroate synthase [Escherichia coli O157:H7] gi\|161485817 - gi\|161485817\|ref\|NP_708976.3\| dihydropteroate synthase [Shigella flexneri 2a str. 301] DHPS_ECOL6 - Dihydropteroate synthase OS=Escherichia coli O6 GN=folP PE=3 SV=1 gi\|168781319, gi... - gi\|189001096\|gb\|EDU70082.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. EC4076], gi\|1687... gi\|189374224, gi... - gi\|189374224\|gb\|EDU92640.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. EC869], gi\|16878... gi\|189379682, gi... - gi\|189379682\|gb\|EDU98098.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. EC508], gi\|16879... gi\|169753501, gi... - gi\|170018573\|ref\|YP_001723527.1\| dihydropteroate synthase [Escherichia coli ATCC 8739], gi\|169753501... gi\|170082712, gi... - gi\|170082712\|ref\|YP_001732032.1\| 7,8-dihydropteroate synthase [Escherichia coli str. K-12 substr. DH... gi\|170682317, gi... - gi\|170682317\|ref\|YP_001745449.1\| dihydropteroate synthase [Escherichia coli SMS-3-5], gi\|170520035\|g... EG50011 - 7,8-dihydropteroate synthase / Dihydropteroate synthase gi\|188491297, gi... - gi\|188496098\|ref\|ZP_03003368.1\| dihydropteroate synthase [Escherichia coli 53638], gi\|188491297\|gb\|E... gi\|195938396 - gi\|195938396\|ref\|ZP_03083778.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. EC4024] DHPS_ECOL6 - Dihydropteroate synthase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=folP PE=3... gi\|38704146 - gi\|38704146\|ref\|NP_312083.2\| dihydropteroate synthase [Escherichia coli O157:H7 str. Sakai] gi\|161486427 - gi\|161486427\|ref\|NP_838686.2\| dihydropteroate synthase [Shigella flexneri 2a str. 2457T] gi\|110643417, gi... - gi\|110643417\|ref\|YP_671147.1\| dihydropteroate synthase [Escherichia coli 536], gi\|110345009\|gb\|ABG71... gi\|161986441 - gi\|161986441\|ref\|YP_312133.2\| dihydropteroate synthase [Shigella sonnei Ss046] gi\|110616591, gi... - gi\|110807043\|ref\|YP_690563.1\| dihydropteroate synthase [Shigella flexneri 5 str. 8401], gi\|110616591... gi\|188016333, gi... - gi\|188016333\|gb\|EDU54455.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. EC4113], gi\|1687... gi\|168754157, gi... - gi\|189358746\|gb\|EDU77165.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. EC4401], gi\|1687... gi\|189367580, gi... - gi\|189367580\|gb\|EDU85996.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. EC4501], gi\|1687... gi\|168769594, gi... - gi\|189361464\|gb\|EDU79883.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. EC4486], gi\|1687... gi\|168773157, gi... - gi\|187770973\|gb\|EDU34817.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. EC4196], gi\|1687... DHPS_ECOLI - Dihydropteroate synthase (EC 2.5.1.15) (DHPS) (Dihydropteroate pyrophosphorylase) - Escherichia coli gi\|254594526, gi... - gi\|254795126\|ref\|YP_003079963.1\| 7,8-dihydropteroate synthase [Escherichia coli O157:H7 str. TW14359... gi\|254163119, gi... - gi\|254163119\|ref\|YP_003046227.1\| 7,8-dihydropteroate synthase [Escherichia coli B str. REL606], gi\|2... gi\|253323033, gi... - gi\|254289869\|ref\|YP_003055617.1\| 7,8-dihydropteroate synthase [Escherichia coli BL21(DE3)], gi\|25397... gi\|242378720, gi... - gi\|251786447\|ref\|YP_003000751.1\| hypothetical protein B21_02993 [Escherichia coli BL21], gi\|24237872... gi\|238859894, gi... - gi\|238902279\|ref\|YP_002928075.1\| 7,8-dihydropteroate synthase [Escherichia coli BW2952], gi\|23885989... gi\|227887898, gi... - gi\|227887898\|ref\|ZP_04005703.1\| dihydropteroate synthase [Escherichia coli 83972], gi\|227835294\|gb\|E... gi\|89109940, gi\|... - gi\|89109940\|ref\|AP_003720.1\| 7,8-dihydropteroate synthase [Escherichia coli str. K-12 substr. W3110]... gi\|191172195, gi... - gi\|75240800\|ref\|ZP_00724698.1\| COG0294: Dihydropteroate synthase and related enzymes [Escherichia co... gi\|193067402, gi... - gi\|75239256\|ref\|ZP_00723227.1\| COG0294: Dihydropteroate synthase and related enzymes [Escherichia co... gi\|191168050, gi... - gi\|75228766\|ref\|ZP_00715375.1\| COG0294: Dihydropteroate synthase and related enzymes [Escherichia co... gi\|75197126, gi\|... - gi\|75197126\|ref\|ZP_00707196.1\| COG0294: Dihydropteroate synthase and related enzymes [Escherichia co... gi\|157081271, gi... - gi\|75187983\|ref\|ZP_00701250.1\| COG0294: Dihydropteroate synthase and related enzymes [Escherichia co... gi\|194438796, gi... - gi\|83585816\|ref\|ZP_00924457.1\| COG0294: Dihydropteroate synthase and related enzymes [Escherichia co... gi\|124525917, gi... - gi\|124525917\|ref\|ZP_01697922.1\| dihydropteroate synthase [Escherichia coli B], gi\|124502021\|gb\|EAY49... gi\|218555747, gi... - gi\|218555747\|ref\|YP_002388660.1\| dihydropteroate synthase [Escherichia coli IAI1], gi\|218362515\|emb\|... gi\|218429031, gi... - gi\|218691467\|ref\|YP_002399679.1\| dihydropteroate synthase [Escherichia coli ED1a], gi\|218429031\|emb\|... gi\|218353614, gi... - gi\|218696882\|ref\|YP_002404549.1\| dihydropteroate synthase [Escherichia coli 55989], gi\|218353614\|emb... gi\|218701946, gi... - gi\|218701946\|ref\|YP_002409575.1\| dihydropteroate synthase [Escherichia coli IAI39], gi\|218371932\|emb... gi\|218706797, gi... - gi\|218706797\|ref\|YP_002414316.1\| dihydropteroate synthase [Escherichia coli UMN026], gi\|218433894\|em... gi\|208807489, gi... - gi\|208807489\|ref\|ZP_03249826.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. EC4206], gi\|... gi\|208734920, gi... - gi\|208813643\|ref\|ZP_03254972.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. EC4045], gi\|... gi\|208741948, gi... - gi\|208821825\|ref\|ZP_03262145.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. EC4042], gi\|... gi\|209158799, gi... - gi\|209397399\|ref\|YP_002272647.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. EC4115], gi... gi\|209920652, gi... - gi\|209920652\|ref\|YP_002294736.1\| dihydropteroate synthase [Escherichia coli SE11], gi\|209913911\|dbj\|... gi\|215488493, gi... - gi\|215488493\|ref\|YP_002330924.1\| dihydropteroate synthase [Escherichia coli O127:H6 str. E2348/69], ... gi\|217319506, gi... - gi\|217327139\|ref\|ZP_03443222.1\| dihydropteroate synthase [Escherichia coli O157:H7 str. TW14588], gi... gi\|218358001, gi... - gi\|218550460\|ref\|YP_002384251.1\| dihydropteroate synthase [Escherichia fergusonii ATCC 35469], gi\|21...	2.0E-96	[1..276]	[1..276]
gi\|606115\|gb\|AAA... - dihydropteroate synthase [Escherichia coli] gi\|13363529 - gi\|13363529\|dbj\|BAB37479.1\| 7,8-dihydropteroate synthase [Escherichia coli O157:H7 str. Sakai] gi\|56480281, gi\|... - gi\|56480281\|ref\|NP_708976.2\| 7,8-dihydropteroate synthase [Shigella flexneri 2a str. 301], gi\|563838... gi\|209758270, gi... - gi\|606115\|gb\|AAA57978.1\| dihydropteroate synthase [Escherichia coli], pir\|\|C85981 7,8-dihydropteroat... gi\|30042774, gi\|... - gi\|30064515\|ref\|NP_838686.1\| 7,8-dihydropteroate synthase [Shigella flexneri 2a str. 2457T], gi\|3004... gi\|13363529 - gi\|13363529\|dbj\|BAB37479.1\| 7,8-dihydropteroate synthase [Escherichia coli O157:H7] gi\|15803717, gi\|... - gi\|15803717\|ref\|NP_289751.1\| 7,8-dihydropteroate synthase [Escherichia coli O157:H7 EDL933], gi\|1251... gi\|49176323, gi\|... - gi\|49176323\|ref\|NP_417644.3\| 7,8-dihydropteroate synthase [Escherichia coli K12], gb\|AAC76209.1\| 7,8...	2.0E-96	[1..276]	[16..291]
gi\|193061963, gi... - gi\|75260105\|ref\|ZP_00731383.1\| COG0294: Dihydropteroate synthase and related enzymes [Escherichia co... gi\|75208501, gi\|... - gi\|75208501\|ref\|ZP_00708821.1\| COG0294: Dihydropteroate synthase and related enzymes [Escherichia co...	3.0E-96	[1..276]	[1..276]

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Predicted Domain #1

Region A:
Residues: [1-277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHLTARGLTL DLSRPQVMGI LNVTPDSFSD GGCHNNLDQA LQHAQRMLSA GATLIDIGGE  60
   61 STRPGAAEVS EQEELDRVVP VVEALAQRFD VWLSVDTSKA AVITESAHAG AHLINDIRSL 120
  121 QEPGALEAAA KTGLPVCLMH MQGQPKNMQH SPYYDDLMTD INRFFQHHIE RCVAAGIAKN 180
  181 KLLLDPGFGF GKNLAHNYQL LAHLSELHHF ELPLLVGMSR KSMVGQLLNV PPQQRVIGSV 240
  241 ACAVIAAMQG AQIIRVHDVK ETVEAMCIVE ATRSAKG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	98.0
Match:	1aj0A
Description:	CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E. COLI DIHYDROPTEROATE SYNTHASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
dihydropteroate synthase activity	5.55484533231129	bayes_pls_golite062009
catalytic activity	1.94758748334979	bayes_pls_golite062009
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	1.59882258515727	bayes_pls_golite062009
transferase activity	1.09979615331123	bayes_pls_golite062009
transferase activity, transferring alkyl or aryl (other than methyl) groups	1.09502814971491	bayes_pls_golite062009
binding	0.691846952184196	bayes_pls_golite062009
dihydroneopterin aldolase activity	0.570043482286316	bayes_pls_golite062009
diphosphotransferase activity	0.246882532482481	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: