YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|38492611, gi\|...
Organism:	Drosophila melanogaster
Length:	230 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|38492611, gi|....

Description	E-value	Query Range	Subject Range
gi\|88191978, gi\|... - gi\|88191978\|pdb\|2A30\|D Chain D, Crystal Structure Of Human Deoxycytidine Kinase In Complex With Deox...	174.0	[0..1]	[229..4]
gi\|220950078, gi... - gi\|220959178\|gb\|ACL92132.1\| dnk-PA [synthetic construct], gi\|220950078\|gb\|ACL87582.1\| dnk-PA [synthe... FBpp0302815, dnk-PA - The gene deoxyribonucleoside kinase is referred to in FlyBase by the symbol Dmel\dnk (CG5452, FBgn00...	171.0	[0..1]	[230..1]
DCK_MOUSE - Deoxycytidine kinase OS=Mus musculus GN=Dck PE=1 SV=1	165.0	[0..1]	[229..1]
gi\|54696740, gi\|... - gi\|61367811\|gb\|AAX43050.1\| deoxycytidine kinase [synthetic construct], gi\|61367804\|gb\|AAX43049.1\| de...	164.0	[0..1]	[229..1]

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Predicted Domain #1

Region A:
Residues: [1-230]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEAASCARK GTKYAEGTQP FTVLIEGNIG SGKTTYLNHF EKYKNDICLL TEPVEKWRNV  60
   61 NGVNLLELMY KDPKKWAMPF QSYVTLTMLQ SHTAPTNKKL KIMERSIFSA RYCFVENMRR 120
  121 NGSLEQGMYN TLEEWYKFIE ESIHVQADLI IYLRTSPEVA YERIRQRARS EESCVPLKYL 180
  181 QELHELHEDW LIHQRRPQSC KVLVLDADLN LENIGTEYQR SESSIFDAIS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	43.0
Match:	1ot3A
Description:	Deoxyribonucleoside kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nucleobase, nucleoside, nucleotide kinase activity	3.66392587433723	bayes_pls_golite062009
nucleotide kinase activity	2.24094813695083	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	1.96697952975573	bayes_pls_golite062009
ribonucleotide binding	1.53142082854758	bayes_pls_golite062009
purine nucleotide binding	1.52938239070386	bayes_pls_golite062009
purine ribonucleotide binding	1.52887308780164	bayes_pls_golite062009
nucleotide binding	1.52746968836881	bayes_pls_golite062009
binding	1.46714820387895	bayes_pls_golite062009
adenylate kinase activity	1.27088333982087	bayes_pls_golite062009
ATP binding	1.23942044024113	bayes_pls_golite062009
adenyl ribonucleotide binding	1.21044170258803	bayes_pls_golite062009
adenyl nucleotide binding	1.19481945569892	bayes_pls_golite062009
kinase activity	1.11120928120082	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	1.00388614309685	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.908046791062776	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	0.872487338145151	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	0.854269100162193	bayes_pls_golite062009
CTP synthase activity	0.554689818807922	bayes_pls_golite062009
nucleic acid binding	0.503971340374059	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.450562042301179	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.421921195209539	bayes_pls_golite062009
hydrolase activity	0.420858111948277	bayes_pls_golite062009
protein binding	0.232442551591362	bayes_pls_golite062009
transferase activity	0.175269600441384	bayes_pls_golite062009
DNA binding	0.111331583742205	bayes_pls_golite062009
protein kinase activity	0.0646123847220056	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: