YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|189000990, gi...
Organism:	Escherichia coli O157:H7 str. EC4076
Length:	890 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|189000990, gi....

Description	E-value	Query Range	Subject Range
gi\|227887891, gi... - gi\|227887891\|ref\|ZP_04005696.1\| translation initiation factor IF-2 [Escherichia coli 83972], gi\|2278... gi\|226899119, gi... - gi\|237706079\|ref\|ZP_04536560.1\| translation initiation factor IF-2 [Escherichia sp. 3_2_53FAA], gi\|2... IF2_ECO45 - Translation initiation factor IF-2 OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=infB PE=3 SV=1 IF2_ECO27 - Translation initiation factor IF-2 OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=infB PE=3... sp\|B7UJ63\|IF2_ECO27 - Translation initiation factor IF-2 OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=infB PE=3... IF2_ECOK1 - Translation initiation factor IF-2 OS=Escherichia coli O1:K1 / APEC GN=infB PE=3 SV=1 IF2_ECOL6 - Translation initiation factor IF-2 OS=Escherichia coli O6 GN=infB PE=3 SV=1 IF2_ECOUT - Translation initiation factor IF-2 OS=Escherichia coli (strain UTI89 / UPEC) GN=infB PE=3 SV=1 gi\|75240807, gi\|... - gi\|75240807\|ref\|ZP_00724705.1\| COG0532: Translation initiation factor 2 (IF-2; GTPase) [Escherichia ... IF2_ECOL6 - Translation initiation factor IF-2 OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN... gi\|2597877, gi\|2... - gi\|2597877\|emb\|CAA05541.1\| Initiation factor IF2-alpha [Escherichia coli], gi\|2597873\|emb\|CAA05538.1... IF2_ECOL5 - Translation initiation factor IF-2 OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=infB PE=3 S...	637.0	[0..1]	[890..1]
IF2_SHISS - Translation initiation factor IF-2 OS=Shigella sonnei (strain Ss046) GN=infB PE=3 SV=1	637.0	[0..1]	[890..1]
IF2_SHIDS - Translation initiation factor IF-2 OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=infB PE=3 SV...	637.0	[0..1]	[890..1]
gi\|15803710, gi\|... - gi\|15803710\|ref\|NP_289744.1\| translation initiation factor IF-2 [Escherichia coli O157:H7 EDL933], g... gi\|25299462 - gi\|25299462\|pir\|\|D85980 protein chain initiation factor IF-2 [imported] - Escherichia coli (strain O...	636.0	[0..1]	[890..1]
IF2_SHIB3 - Translation initiation factor IF-2 OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS512) GN=in...	636.0	[0..1]	[890..1]
gi\|2597869 - gi\|2597869\|emb\|CAA05535.1\| Initiation factor IF2-alpha [Escherichia coli]	636.0	[0..1]	[890..1]
IF2_SHIBS - Translation initiation factor IF-2 OS=Shigella boydii serotype 4 (strain Sb227) GN=infB PE=3 SV=1 gi\|24114459, gi\|... - gi\|24114459\|ref\|NP_708969.1\| translation initiation factor IF-2 [Shigella flexneri 2a str. 301], gi\|... gi\|30064508, gi\|... - gi\|30064508\|ref\|NP_838679.1\| translation initiation factor IF-2 [Shigella flexneri 2a str. 2457T], g... IF2_SHIFL - Translation initiation factor IF-2 OS=Shigella flexneri GN=infB PE=3 SV=1	631.0	[0..1]	[890..1]
IF2_SHIF8 - Translation initiation factor IF-2 OS=Shigella flexneri serotype 5b (strain 8401) GN=infB PE=3 SV=1	630.0	[0..1]	[890..1]

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Predicted Domain #1

Region A:
Residues: [1-228]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDVTIKTLA AERQTSVERL VQQFADAGIR KSADDSVSAQ EKQTLIDHLN QKNSGPDKLT  60
   61 LQRKTRSTLN IPGTGGKSKS VQIEVRKKRT FVKRDPQEAE RLAAEEQAQR EAEEQARREA 120
  121 EESAKREAQQ KAEREAAEQA KREAAEQAKR EAAEKDKVSN QQDDMTKNAQ AEKARREQEA 180
  181 AELKRKAEEE ARRKLEEEAR RVAEEARRMA EENKWTDNAE PTEDSSDY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.69897
Match:	1i84S
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [229-383]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HVTTSQHARQ AEDESDREVE GGRGRGRNAK AARPKKGNKH AESKADREEA RAAVRGGKGG  60
   61 KRKGSSLQQG FQKPAQAVNR DVVIGETITV GELANKMAVK GSQVIKAMMK LGAMATINQV 120
  121 IDQETAQLVA EEMGHKVILR RENELEEAVM SDRDT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.69897
Match:	2e87A
Description:	No description for 2e87A was found.

Predicted Domain #3

Region A:
Residues: [384-890]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAAAEPRAPV VTIMGHVDHG KTSLLDYIRS TKVASGEAGG ITQHIGAYHV ETENGMITFL  60
   61 DTPGHAAFTS MRARGAQATD IVVLVVAADD GVMPQTIEAI QHAKAAQVPV VVAVNKIDKP 120
  121 EADPDRVKNE LSQYGILPEE WGGESQFVHV SAKAGTGIDE LLDAILLQAE VLELKAVRKG 180
  181 MASGAVIESF LDKGRGPVAT VLVREGTLHK GDIVLCGFEY GRVRAMRNEL GQEVLEAGPS 240
  241 IPVEILGLSG VPAAGDEVTV VRDEKKAREV ALYRQGKFRE VKLARQQKSK LENMFANMTE 300
  301 GEVHEVNIVL KADVQGSVEA ISDSLLKLST DEVKVKIIGS GVGGITETDA TLAAASNAIL 360
  361 VGFNVRADAS ARKVIEAESL DLRYYSVIYN LIDEVKAAMS GMLSPELKQQ IIGLAEVRDV 420
  421 FKSPKFGAIA GCMVTEGVVK RHNPIRVLRD NVVIYEGELE SLRRFKDDVN EVRNGMECGI 480
  481 GVKNYNDVRT GDVIEVFEII EIQRTIA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	126.0
Match:	1zo1I
Description:	IF2, IF1, and tRNA fitted to cryo-EM data OF E. COLI 70S initiation complex
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits