YRC Public Data Repository - Protein Structure Prediction

Protein:	KHSE_STRPJ
Organism:	Streptococcus pneumoniae ATCC 700669
Length:	289 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KHSE_STRPJ.

Description	E-value	Query Range	Subject Range
gi\|1498295 - gi\|1498295\|gb\|AAC44297.1\| homoserine kinase-like protein [Streptococcus pneumoniae]	226.0	[0..1]	[289..1]
gi\|227553950, gi... - gi\|227553950\|ref\|ZP_03983997.1\| homoserine kinase [Enterococcus faecalis HH22], gi\|227176936\|gb\|EEI5... KHSE_ENTFA - Homoserine kinase OS=Enterococcus faecalis (strain ATCC 700802 / V583) GN=thrB PE=3 SV=1 KHSE_ENTFA - Homoserine kinase OS=Enterococcus faecalis GN=thrB PE=3 SV=1	224.0	[0..1]	[286..1]
KHSE_BACWK - Homoserine kinase OS=Bacillus weihenstephanensis (strain KBAB4) GN=thrB PE=3 SV=1	224.0	[0..2]	[289..5]
KHSE_BACC1 - Homoserine kinase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=thrB PE=3 SV=1	224.0	[0..3]	[289..6]
KHSE_BACCR - Homoserine kinase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 937...	223.0	[0..3]	[289..6]
KHSE_LISIN - Homoserine kinase OS=Listeria innocua GN=thrB PE=3 SV=1 KHSE_LISIN - Homoserine kinase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=thrB PE=3 SV=1	223.0	[0..1]	[286..1]
gi\|74489438, gi\|... - gi\|75763073\|ref\|ZP_00742857.1\| Homoserine kinase [Bacillus thuringiensis serovar israelensis ATCC 35...	223.0	[0..3]	[289..6]
KHSE_BACCZ - Homoserine kinase OS=Bacillus cereus (strain ZK / E33L) GN=thrB PE=3 SV=1	222.0	[0..3]	[289..6]
gi\|47570003, gi\|... - gi\|47570003\|ref\|ZP_00240666.1\| homoserine kinase [Bacillus cereus G9241], gi\|47553351\|gb\|EAL11739.1\|...	222.0	[0..3]	[289..6]
KHSE_BACHK - Homoserine kinase OS=Bacillus thuringiensis subsp. konkukian GN=thrB PE=3 SV=1 gi\|254721322 - gi\|254721322\|ref\|ZP_05183112.1\| homoserine kinase [Bacillus anthracis str. A1055] KHSE_BACC0 - Homoserine kinase OS=Bacillus cereus (strain AH820) GN=thrB PE=3 SV=1 KHSE_BACHK - Homoserine kinase OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=thrB PE=3 SV=1 gi\|195990432, gi... - gi\|196036959\|ref\|ZP_03104336.1\| homoserine kinase [Bacillus cereus W], gi\|195990432\|gb\|EDX54423.1\| h...	221.0	[0..3]	[289..6]

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Predicted Domain #1

Region A:
Residues: [1-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIIVPATSA NIGPGFDSVG VAVTKYLQIE VCEERDEWLI EHQIGKWIPH DERNLLLKIA  60
   61 LQIVPDLQPR RLKMTSDVPL ARGLGSSSSV IVAGIELANQ LGQLNLSDHE KLQLATKIEG 120
  121 HPDNVAPAIY GNLVIASSVE GQVSAIVADF PECDFLAYIP NYELRTRDSR SVLPKKLSYK 180
  181 EAVAASSIAN VAVAALLAGD MVTAGQAIEG DLFHERYRQD LVREFAMIKQ VTKENGAYAT 240
  241 YLSGAGPTVM VLASHDKMPT IKAELEKQPF KGKLHDLRVD TQGVRVEAK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.39794
Match:	1fwkA
Description:	Homoserine kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.836142537655721	bayes_pls_golite062009
structural constituent of ribosome	0.0246382239358082	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: