YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|166960212, gi...
Organism:	Yersinia pestis biovar Orientalis str. MG05-1020
Length:	196 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|166960212, gi....

Description	E-value	Query Range	Subject Range
gi\|77962463 - gi\|77962463\|ref\|ZP_00826283.1\| COG0118: Glutamine amidotransferase [Yersinia mollaretii ATCC 43969]	9.0E-48	[1..196]	[1..196]
gi\|77978865 - gi\|77978865\|ref\|ZP_00834289.1\| COG0118: Glutamine amidotransferase [Yersinia intermedia ATCC 29909]	9.0E-48	[1..196]	[1..196]
gi\|77975878 - gi\|77975878\|ref\|ZP_00831412.1\| COG0118: Glutamine amidotransferase [Yersinia frederiksenii ATCC 3364...	1.0E-47	[1..196]	[1..196]
gi\|77959283 - gi\|77959283\|ref\|ZP_00823304.1\| COG0118: Glutamine amidotransferase [Yersinia bercovieri ATCC 43970]	3.0E-47	[1..196]	[1..196]
gi\|192955120, gi... - gi\|75214869\|ref\|ZP_00713350.1\| COG0118: Glutamine amidotransferase [Escherichia coli E110019], gi\|19... gi\|194428759, gi... - gi\|75210033\|ref\|ZP_00710216.1\| COG0118: Glutamine amidotransferase [Escherichia coli B171], gi\|19442...	6.0E-47	[1..196]	[1..196]
HIS5_SHIFL - Imidazole glycerol phosphate synthase subunit HisH OS=Shigella flexneri GN=hisH PE=3 SV=1 gi\|24052430, gi\|... - gi\|24113408\|ref\|NP_707918.1\| imidazole glycerol phosphate synthase subunit HisH [Shigella flexneri 2... gi\|110615544, gi... - gi\|110805996\|ref\|YP_689516.1\| imidazole glycerol phosphate synthase subunit HisH [Shigella flexneri ... gi\|30063473, gi\|... - gi\|30063473\|ref\|NP_837644.1\| imidazole glycerol phosphate synthase subunit HisH [Shigella flexneri 2...	6.0E-46	[1..196]	[1..196]
gi\|189355492, gi... - gi\|189355492\|gb\|EDU73911.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|188014321, gi... - gi\|188014321\|gb\|EDU52443.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... EG10450 - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit / Imidazole glycerol phosp... HIS5_ECOL6 - Imidazole glycerol phosphate synthase subunit HisH OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 7... EG10450 - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit / Imidazole glycerol phosp... HIS5_SHISS - Imidazole glycerol phosphate synthase subunit HisH OS=Shigella sonnei (strain Ss046) GN=hisH PE=3 SV... gi\|208817155, gi... - gi\|208817155\|ref\|ZP_03258247.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|75514064, gi\|... - gi\|75514064\|ref\|ZP_00736394.1\| COG0118: Glutamine amidotransferase [Escherichia coli 53638], gi\|1884... gi\|208727400, gi... - gi\|208807599\|ref\|ZP_03249936.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|75259172, gi\|... - gi\|75259172\|ref\|ZP_00730520.1\| COG0118: Glutamine amidotransferase [Escherichia coli E22], gi\|193062... gi\|209396111, gi... - gi\|209396111\|ref\|YP_002271264.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|190909636, gi... - gi\|75242856\|ref\|ZP_00726562.1\| COG0118: Glutamine amidotransferase [Escherichia coli F11], gi\|191170... gi\|208818954, gi... - gi\|208818954\|ref\|ZP_03259274.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|215487245, gi... - gi\|215487245\|ref\|YP_002329676.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col... gi\|209919488, gi... - gi\|209919488\|ref\|YP_002293572.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col... HIS5_SHIBS - Imidazole glycerol phosphate synthase subunit HisH OS=Shigella boydii serotype 4 (strain Sb227) GN=h... gi\|218361354, gi... - gi\|218554586\|ref\|YP_002387499.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col... HIS5_SHIDS - Imidazole glycerol phosphate synthase subunit HisH OS=Shigella dysenteriae serotype 1 (strain Sd197)... gi\|218549437, gi... - gi\|218549437\|ref\|YP_002383228.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia fer... gi\|194420392, gi... - gi\|83571263\|ref\|ZP_00922704.1\| COG0118: Glutamine amidotransferase [Shigella dysenteriae 1012], gi\|1... gi\|187769010, gi... - gi\|187769010\|gb\|EDU32854.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|194424981, gi... - gi\|83588024\|ref\|ZP_00926649.1\| COG0118: Glutamine amidotransferase [Escherichia coli 101-1], gi\|1944... gi\|189361197, gi... - gi\|189361197\|gb\|EDU79616.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|89108844, gi\|... - gi\|89108844\|ref\|AP_002624.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subun... gi\|168788689, gi... - gi\|189371592\|gb\|EDU90008.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|237704479, gi... - gi\|237704479\|ref\|ZP_04534960.1\| imidazole glycerol phosphate synthase subunit hisH [Escherichia sp. ... gi\|91211309, gi\|... - gi\|91211309\|ref\|YP_541295.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia coli UT... gi\|115513350, gi... - gi\|117624226\|ref\|YP_853139.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia coli A... gi\|168782304, gi... - gi\|189000084\|gb\|EDU69070.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|238901214, gi... - gi\|238901214\|ref\|YP_002927010.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|190902231, gi... - gi\|75229116\|ref\|ZP_00715691.1\| COG0118: Glutamine amidotransferase [Escherichia coli B7A], gi\|191167... gi\|124530722, gi... - gi\|124530722\|ref\|ZP_01701279.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|169754578, gi... - gi\|170019650\|ref\|YP_001724604.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col... gi\|254593205, gi... - gi\|254793805\|ref\|YP_003078642.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|75177150, gi\|... - gi\|75177150\|ref\|ZP_00697248.1\| COG0118: Glutamine amidotransferase [Shigella boydii BS512], gi\|18773... gi\|189378497, gi... - gi\|189378497\|gb\|EDU96913.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|195939361 - gi\|195939361\|ref\|ZP_03084743.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia coli... gi\|169889489, gi... - gi\|170081654\|ref\|YP_001730974.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|110343828, gi... - gi\|110642236\|ref\|YP_669966.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia coli 5... HIS5_ECOL6 - Imidazole glycerol phosphate synthase subunit HisH OS=Escherichia coli O6 GN=hisH PE=3 SV=1 HIS5_ECOLI - Imidazole glycerol phosphate synthase subunit hisH (EC 2.4.2.-) (IGP synthase glutamine amidotransfe... gi\|218369374, gi... - gi\|218699388\|ref\|YP_002407017.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col... gi\|218695649, gi... - gi\|218695649\|ref\|YP_002403316.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col... gi\|168986347 - gi\|168986347\|dbj\|BAG11886.1\| imidazole glycerol phosphate synthase [Escherichia coli O55:H7] gi\|218705562, gi... - gi\|218705562\|ref\|YP_002413081.1\| imidazole glycerol phosphate synthase subunit HisH [Escherichia col...	8.0E-46	[1..196]	[1..196]
HIS5_SALPA - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella paratyphi A (strain ATCC 9150 / SAR... HIS5_SALPA - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella paratyphi A GN=hisH PE=3 SV=1 HIS5_SALCH - Imidazole glycerol phosphate synthase subunit hisH OS=Salmonella choleraesuis GN=hisH PE=3 SV=2 HIS5_SALTY - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella typhimurium GN=hisH PE=3 SV=1 HIS5_SALCH - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella choleraesuis GN=hisH PE=3 SV=2 gi\|197263884, gi... - gi\|197263884\|ref\|ZP_03163958.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|194738319, gi... - gi\|194738319\|ref\|YP_002115162.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|194472955, gi... - gi\|194472955\|ref\|ZP_03078939.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|194447980, gi... - gi\|194447980\|ref\|YP_002046125.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella ente... gi\|204321513, gi... - gi\|204928969\|ref\|ZP_03220112.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|199605427, gi... - gi\|200388329\|ref\|ZP_03214941.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase su... gi\|197937908, gi... - gi\|198243392\|ref\|YP_002216161.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|197093427, gi... - gi\|197361950\|ref\|YP_002141587.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella ente... HIS5_SALTY - Imidazole glycerol phosphate synthase subunit hisH OS=Salmonella typhimurium GN=hisH PE=3 SV=1 gi\|168236227, gi... - gi\|197290515\|gb\|EDY29870.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|168229394, gi... - gi\|205335634\|gb\|EDZ22398.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|167990989, gi... - gi\|205330592\|gb\|EDZ17356.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... HIS5_SALTY - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella typhimurium (strain LT2 / SGSC1412 ... gi\|161362612, gi... - gi\|161613248\|ref\|YP_001587213.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella ente... HIS5_SALCH - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella choleraesuis (strain SC-B67) GN=his... gi\|194443517, gi... - gi\|194443517\|ref\|YP_002041343.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase s... gi\|168818233, gi... - gi\|205345002\|gb\|EDZ31766.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|205351156, gi... - gi\|205351156\|gb\|EDZ37787.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|168242147, gi... - gi\|205338562\|gb\|EDZ25326.1\| imidazole glycerol phosphate synthase, glutamine amidotransferase subuni... gi\|16761006 - gi\|16761006\|ref\|NP_456623.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enterica... gi\|213648076 - gi\|213648076\|ref\|ZP_03378129.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... gi\|213622708 - gi\|213622708\|ref\|ZP_03375491.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... gi\|213425566 - gi\|213425566\|ref\|ZP_03358316.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... gi\|213161019 - gi\|213161019\|ref\|ZP_03346729.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... gi\|224583428, gi... - gi\|224583428\|ref\|YP_002637226.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella ente... gi\|214001358 - gi\|214001358\|ref\|ZP_03412093.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... gi\|213859453 - gi\|213859453\|ref\|ZP_03385157.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... gi\|238913443 - gi\|238913443\|ref\|ZP_04657280.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enter... lcl\|NC_016856.1_... - [gene=hisH] [protein=imidazole glycerol phosphate synthase subunit HisH] [protein_id=YP_005238110.2]... HIS5_SALTI - Imidazole glycerol phosphate synthase subunit HisH OS=Salmonella typhi GN=hisH PE=3 SV=1 gi\|29136924, gi\|... - gi\|29141298\|ref\|NP_804640.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enterica... HIS5_SALTI - Imidazole glycerol phosphate synthase subunit hisH OS=Salmonella typhi GN=hisH PE=3 SV=1	1.0E-45	[1..196]	[1..196]
HIS5_PHOLL - Imidazole glycerol phosphate synthase subunit HisH OS=Photorhabdus luminescens subsp. laumondii (str... HIS5_PHOLL - Imidazole glycerol phosphate synthase subunit hisH OS=Photorhabdus luminescens subsp. laumondii GN=h...	1.0E-45	[1..196]	[1..201]
gi\|16765405, gi\|... - gi\|16765405\|ref\|NP_461020.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella typhimur... gi\|207857510, gi... - gi\|207857510\|ref\|YP_002244161.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella ente... gi\|205272998, gi... - gi\|205353217\|ref\|YP_002227018.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella ente... gi\|62128288, gi\|... - gi\|62180655\|ref\|YP_217072.1\| imidazole glycerol phosphate synthase subunit HisH [Salmonella enterica...	1.0E-45	[1..196]	[2..197]

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Predicted Domain #1

Region A:
Residues: [1-196]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVVILDTGC ANLSSVTYAV QRLGYTPVIS RDPAVVLRAD KLFMPGVGTA HAAMEQLRQR  60
   61 ELIELIKSCT QPVLGICLGM QLLATSSEES GGITTLGMID APVKKMTDFG LPLPHMGWNQ 120
  121 ITAQAGNHLF RGIPDGTYFY FVHGYAMPIC PNTIAQTNYG EPFTAAVEKD NFFGVQFHPE 180
  181 RSGAAGAQLM KNFLEM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.154902
Match:	1jvnA
Description:	Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF; GAT subunit, HisH, (or domain) of imidazoleglycerolphosphate synthase HisF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
imidazoleglycerol-phosphate synthase activity	8.34101262147614	bayes_pls_golite062009
ligase activity	1.70348758031146	bayes_pls_golite062009
catalytic activity	1.30391542469987	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	0.643287540591989	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.628648036096965	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: