YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|215444757
Organism:	Mycobacterium tuberculosis T85
Length:	161 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|215444757.

Description	E-value	Query Range	Subject Range
gi\|41410208, gi\|... - gi\|41410208\|ref\|NP_963044.1\| preprotein translocase subunit SecE [Mycobacterium avium subsp. paratub...	154.0	[0..1]	[161..1]
SECE_MYCLE - Probable preprotein translocase subunit secE OS=Mycobacterium leprae GN=secE PE=3 SV=1 SECE_MYCLE - Protein translocase subunit SecE OS=Mycobacterium leprae (strain TN) GN=secE PE=3 SV=1 gi\|221230498, gi... - gi\|221230498\|ref\|YP_002503914.1\| SecE preprotein translocase [Mycobacterium leprae Br4923], gi\|21993...	146.0	[0..1]	[161..1]
gi\|145218180, gi... - gi\|89338460\|ref\|ZP_01191225.1\| SecE subunit of protein translocation complex [Mycobacterium flavesce...	123.0	[0..1]	[160..1]
gi\|92432232, gi\|... - gi\|92910144\|ref\|ZP_01278920.1\| SecE subunit of protein translocation complex [Mycobacterium sp. JLS]...	115.0	[0..1]	[161..61]
gi\|108797895, gi... - gi\|108797895\|ref\|YP_638092.1\| preprotein translocase subunit SecE [Mycobacterium sp. MCS], gi\|108768... gi\|119693079, gi... - gi\|92913608\|ref\|ZP_01282236.1\| SecE subunit of protein translocation complex [Mycobacterium sp. KMS]...	113.0	[0..1]	[161..1]
gi\|120402245, gi... - gi\|90202746\|ref\|ZP_01205392.1\| SecE subunit of protein translocation complex [Mycobacterium vanbaale...	113.0	[0..1]	[160..1]
SECE_STRGB - Protein translocase subunit SecE OS=Streptomyces galbus GN=secE PE=3 SV=1	106.0	[0..67]	[161..2]
gi\|38199303 - gi\|38199303\|emb\|CAE48934.1\| Putative translocase protein [Corynebacterium diphtheriae] gi\|38233044 - gi\|38233044\|ref\|NP_938811.1\| preprotein translocase subunit SecE [Corynebacterium diphtheriae NCTC 1...	102.0	[0..45]	[160..11]
gi\|849061, gi\|74... - gi\|849061\|dbj\|BAA09300.1\| SecE like protein [Streptomyces virginiae], gi\|7481911\|pir\|\|T11787 probabl...	92.0	[0..41]	[161..11]
gi\|75255008 - gi\|75255008\|ref\|ZP_00726929.1\| COG0690: Preprotein translocase subunit SecE [Escherichia coli E22]	88.0	[0..89]	[161..52]

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Predicted Domain #1

Region A:
Residues: [1-87]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDEGDVADE AVADGAENAD SRGSGGRTAL VTKPVVRPQR PTGKRSRSRA AGADADVDVE  60
   61 EPSTAASEAT GVAKDDSTTK AVSKAAR

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.390	a.64.1	Saposin
View	Download	0.261	a.83.1	Guanido kinase N-terminal domain
View	Download	0.253	a.60.3	C-terminal domain of RNA polymerase alpha subunit
View	Download	0.412	c.9.1	Barstar (barnase inhibitor)
View	Download	0.328	a.179.1	Replisome organizer (g39p helicase loader/inhibitor protein)

Predicted Domain #2

Region A:
Residues: [88-161]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKKASKPKAR SVNPIAFVYN YLKQVVAEMR KVIWPNRKQM LTYTSVVLAF LAFMVALVAG  60
   61 ADLGLTKLVM LVFG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.69897
Match:	2akhZ
Description:	Normal mode-based flexible fitted coordinates of a non-translocating SecYEG protein-conducting channel into the cryo-EM map of a SecYEG-nascent chain-70S ribosome complex from E. coli
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits