YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|190561157, gi...
Organism:	Bacillus anthracis Tsiankovskii-I
Length:	105 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190561157, gi....

Description	E-value	Query Range	Subject Range
gi\|47553315, gi\|... - gi\|47570016\|ref\|ZP_00240678.1\| PTS system, IIA component [Bacillus cereus G9241], gi\|47569710\|ref\|ZP...	4.0E-30	[1..105]	[1..105]
gi\|218543335, gi... - gi\|218900332\|ref\|YP_002448743.1\| PTS system, cellobiose-specific IIA component [Bacillus cereus G984... gi\|228961452, gi... - gi\|228961452\|ref\|ZP_04123064.1\| Lichenan-specific phosphotransferase enzyme IIA component [Bacillus ... gi\|206970429, gi... - gi\|206970429\|ref\|ZP_03231382.1\| PTS system, cellobiose-specific IIA component [Bacillus cereus AH113... gi\|228903686, gi... - gi\|228903686\|ref\|ZP_04067806.1\| Lichenan-specific phosphotransferase enzyme IIA component [Bacillus ... gi\|229050875, gi... - gi\|229050875\|ref\|ZP_04194427.1\| Lichenan-specific phosphotransferase enzyme IIA component [Bacillus ... gi\|30023247, gi\|... - gi\|30023247\|ref\|NP_834878.1\| PTS system, lichenan oligosaccharide-specific IIA component [Bacillus c... gi\|228968330, gi... - gi\|228968330\|ref\|ZP_04129326.1\| Lichenan-specific phosphotransferase enzyme IIA component [Bacillus ... gi\|75759426, gi\|... - gi\|75759426\|ref\|ZP_00739520.1\| PTS system, lichenan oligosaccharide-specific IIA component [Bacillus... gi\|228602047, gi... - gi\|229181472\|ref\|ZP_04308800.1\| Lichenan-specific phosphotransferase enzyme IIA component [Bacillus ...	4.0E-30	[1..105]	[1..105]
gi\|81429146, gi\|... - gi\|81429146\|ref\|YP_396147.1\| putative cellobiose-specific phosphotransferasesystem, enzyme IIA [Lact...	2.0E-29	[2..104]	[4..106]
PTLA_LACLL - Lactose-specific phosphotransferase enzyme IIA component OS=Lactococcus lactis subsp. lactis GN=lacF... gi\|97953, gi\|321... - pir\|\|A23696 phosphotransferase system enzyme III (EC 2.7.-.-) - Lactococcus lactis, gi\|3212515\|pdb\|...	1.0E-28	[2..103]	[4..105]
gi\|25287978 - pir\|\|H97264 PTS system lactose-specific enzyme IIA [imported] - Clostridium acetobutylicum gi\|15896218, gi\|... - gi\|15896218\|ref\|NP_349567.1\| PTS system lactose-specific enzyme IIA [Clostridium acetobutylicum ATCC...	1.0E-28	[2..102]	[4..104]
gi\|76574895 - gi\|76574895\|gb\|ABA47365.1\| PTS system, lactose-specific IIA component [Lactococcus lactis] gi\|116326611, gi... - gi\|116326611\|ref\|YP_796531.1\| cellobiose-specific PTS system IIA component [Lactococcus lactis subsp...	1.0E-28	[2..103]	[4..105]
gi\|163865092, gi... - gi\|89205076\|ref\|ZP_01183649.1\| Phosphotransferase system PTS, lactose/cellobiose-specific IIA subuni... gi\|228746980, gi... - gi\|229014380\|ref\|ZP_04171499.1\| Lichenan-specific phosphotransferase enzyme IIA component [Bacillus ... gi\|228613635, gi... - gi\|229169921\|ref\|ZP_04297617.1\| Lichenan-specific phosphotransferase enzyme IIA component [Bacillus ... gi\|229136021, gi... - gi\|229136021\|ref\|ZP_04264780.1\| Lichenan-specific phosphotransferase enzyme IIA component [Bacillus ...	1.0E-28	[1..105]	[1..105]
gi\|209560067, gi... - gi\|209560067\|ref\|YP_002286539.1\| PTS system, lactose-specific IIA component (EIIA-Lac) (Lactose- per... gi\|94542775, gi\|... - gi\|94989267\|ref\|YP_597368.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|94995127, gi\|... - gi\|94995127\|ref\|YP_603225.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|139474414, gi... - gi\|139474414\|ref\|YP_001129130.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes ... gi\|71911447, gi\|... - gi\|71911447\|ref\|YP_282997.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|56808782 - gi\|56808782\|ref\|ZP_00366498.1\| COG1447: Phosphotransferase system cellobiose-specific component IIA ... gi\|71803381, gi\|... - gi\|71904286\|ref\|YP_281089.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|21905403, gi\|... - gi\|21911191\|ref\|NP_665459.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|28811819, gi\|... - gi\|28896565\|ref\|NP_802915.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes SSI-... gi\|94544720, gi\|... - gi\|94991212\|ref\|YP_599312.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|19749076, gi\|... - gi\|19749076\|gb\|AAL98472.1\| putative PTS system, lactose-specific component IIA [Streptococcus pyogen... gi\|94546664, gi\|... - gi\|94993156\|ref\|YP_601255.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|50914989, gi\|... - gi\|50914989\|ref\|YP_060961.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes MGAS... gi\|15675727, gi\|... - gi\|15675727\|ref\|NP_269901.1\| PTS system, lactose-specific IIA component [Streptococcus pyogenes M1 G...	2.0E-28	[2..103]	[4..105]
gi\|48869880, gi\|... - gi\|48869880\|ref\|ZP_00322617.1\| COG1447: Phosphotransferase system cellobiose-specific component IIA ...	2.0E-28	[2..103]	[5..106]
gi\|147922098, gi... - gi\|148985794\|ref\|ZP_01818922.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|183576574, gi... - gi\|183576574\|gb\|EDT97102.1\| lactose-specific phosphotransferase enzyme iia component (pts system lac... gi\|183577168, gi... - gi\|183577168\|gb\|EDT97696.1\| lactose-specific phosphotransferase enzyme iia component (pts system lac... gi\|183572551, gi... - gi\|183572551\|gb\|EDT93079.1\| lactose-specific phosphotransferase enzyme iia component (pts system lac... gi\|168491109, gi... - gi\|183574521\|gb\|EDT95049.1\| lactose-specific phosphotransferase enzyme iia component (pts system lac... gi\|116077175, gi... - gi\|116516599\|ref\|YP_816522.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae D... gi\|172043544, gi... - gi\|172043544\|gb\|EDT51590.1\| lactose-specific phosphotransferase enzyme iia component (pts system lac... gi\|168486510, gi... - gi\|183570441\|gb\|EDT90969.1\| lactose-specific phosphotransferase enzyme iia component (pts system lac... gi\|25287982 - pir\|\|F98005 PTS system, lactose-specific IIA component (EC 2.7.-.-) [imported] - Streptococcus pneum... gi\|15458693, gi\|... - gi\|15903114\|ref\|NP_358664.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae R6... gi\|149026434, gi... - gi\|149026434\|ref\|ZP_01836571.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|147760391, gi... - gi\|149008152\|ref\|ZP_01831671.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|149004138, gi... - gi\|149004138\|ref\|ZP_01828941.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|148999049, gi... - gi\|148999049\|ref\|ZP_01826481.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|147926867, gi... - gi\|148995099\|ref\|ZP_01824006.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|148990442, gi... - gi\|148990442\|ref\|ZP_01821600.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|225724966, gi... - gi\|225856861\|ref\|YP_002738372.1\| lactose-specific phosphotransferase enzyme iia component (pts syste... gi\|225854658, gi... - gi\|225854658\|ref\|YP_002736170.1\| lactose-specific phosphotransferase enzyme iia component (pts syste... gi\|242245443, gi... - gi\|242245443\|ref\|ZP_04799880.1\| PTS system, lactose-specific IIA component [Streptococcus pneumoniae... gi\|237822459 - gi\|237822459\|ref\|ZP_04598304.1\| lactose-specific phosphotransferase enzyme iia component (pts system... gi\|237649550 - gi\|237649550\|ref\|ZP_04523802.1\| lactose-specific phosphotransferase enzyme iia component (pts system... gi\|225726993, gi... - gi\|225860972\|ref\|YP_002742481.1\| lactose-specific phosphotransferase enzyme iia component (pts syste... gi\|194398361, gi... - gi\|194398361\|ref\|YP_002037793.1\| PTS system, IIA component [Streptococcus pneumoniae G54], gi\|194358... gi\|221231894, gi... - gi\|221231894\|ref\|YP_002511046.1\| PTS system, lactose-specific IIA component [Streptococcus pneumonia... gi\|168995239, gi... - gi\|169832737\|ref\|YP_001694627.1\| lactose-specific phosphotransferase enzyme IIA component [Streptoco... gi\|182629414, gi... - gi\|182684080\|ref\|YP_001835827.1\| PTS system, lactose-specific IIA component [Streptococcus pneumonia...	2.0E-28	[2..100]	[4..102]

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Predicted Domain #1

Region A:
Residues: [1-105]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTIETKAFH LILHGGNARS CSMEAIDCAK RGEFTEAEAK LQEALEELKE AHRVQTDLIQ  60
   61 KEAGGEKTEV TLLMVHAQDH LMNAITVKEL ASEFVELYRK MSVTE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.30103
Match:	1e2aA
Description:	Enzyme IIa from lactose specific PTS, IIa-lac
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity	5.00429001244066	bayes_pls_golite062009
carbohydrate transmembrane transporter activity	4.03872487639957	bayes_pls_golite062009
transporter activity	1.32957030120524	bayes_pls_golite062009
transmembrane transporter activity	1.20211801626802	bayes_pls_golite062009
active transmembrane transporter activity	1.08511657750399	bayes_pls_golite062009
substrate-specific transporter activity	0.93495816074069	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	0.81702015470704	bayes_pls_golite062009
binding	0.569728786489819	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.34582307123923	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.0202700968382801	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: