YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|37927467
Organism:	Homo sapiens
Length:	185 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|37927467.

Description	E-value	Query Range	Subject Range
gi\|73975379 - gi\|73975379\|ref\|XP_539306.2\| PREDICTED: similar to Mps one binder kinase activator-like 1A (Mob1 hom...	328.0	[0..2]	[185..215]
gi\|109103421 - gi\|109103421\|ref\|XP_001107567.1\| PREDICTED: similar to Mob4B protein [Macaca mulatta]	311.0	[0..2]	[185..75]
gi\|114578135 - gi\|114578135\|ref\|XP_001154085.1\| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]	311.0	[0..2]	[185..75]
gi\|253723086, gi... - gi\|55669621\|pdb\|1R3B\|A Chain A, Solution Structure Of Xenopus Laevis Mob1, gi\|253723086\|pdb\|1R3B\|A C...	309.0	[0..3]	[185..20]
gi\|47226439 - gi\|47226439\|emb\|CAG08455.1\| unnamed protein product [Tetraodon nigroviridis]	309.0	[0..2]	[185..28]
gi\|10435207 - gi\|10435207\|dbj\|BAB14525.1\| unnamed protein product [Homo sapiens]	308.0	[0..2]	[185..33]
MOL1B_PONPY - Mps one binder kinase activator-like 1B - Pongo pygmaeus (Orangutan) gi\|55606148 - gi\|55606148\|ref\|XP_515735.1\| PREDICTED: Mob4B protein isoform 4 [Pan troglodytes] tr\|G1SUR2\|G1SUR2... - Uncharacterized protein OS=Oryctolagus cuniculus GN=MOB1A PE=4 SV=2 MOB1A_MOUSE - MOB kinase activator 1A OS=Mus musculus GN=Mob1a PE=2 SV=3 MOBKL1B - MOB1, Mps One Binder kinase activator-like 1B (yeast) MOB1A_PONAB - MOB kinase activator 1A OS=Pongo abelii GN=MOB1A PE=2 SV=3 MOB1A_RAT - MOB kinase activator 1A OS=Rattus norvegicus GN=Mob1a PE=2 SV=3 gi\|111305145, gi... - gi\|76628940\|ref\|XP_871266.1\| PREDICTED: similar to Mob4B protein [Bos taurus], gi\|115496426\|ref\|NP_0... gi\|73980517 - gi\|73980517\|ref\|XP_852858.1\| PREDICTED: similar to Mob4B protein isoform 1 [Canis familiaris]	308.0	[0..2]	[185..33]
gi\|50746669 - gi\|50746669\|ref\|XP_420601.1\| PREDICTED: similar to MOB1, Mps One Binder kinase activator-like 1A (ye...	306.0	[0..2]	[185..33]

Back

Predicted Domain #1

Region A:
Residues: [1-185]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEATLGSGNL RQAVMLPEGE DLNEWIAVNT VDFFNQINML YGTITEFCTE ASCPVMSAGP  60
   61 RYEYHWADGT NIKKPIKCSA PKYIDYLMTW VQDQLDDETL FPSKIGVPFP KNFMSVAKTI 120
  121 LKRLFRVYAH IYHQHFDSVM QLQEEAHLNT SFKHFIFFVQ EFNLIDRREL APLQELIEKL 180
  181 GSKDR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	84.522879
Match:	1r3bA
Description:	Solution structure of xenopus laevis Mob1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.92301852481284	bayes_pls_golite062009
kinase regulator activity	1.89112613830997	bayes_pls_golite062009
enzyme regulator activity	1.85961781963242	bayes_pls_golite062009
protein binding	1.70532605681329	bayes_pls_golite062009
protein kinase regulator activity	1.22656624834768	bayes_pls_golite062009
enzyme activator activity	1.01199608762933	bayes_pls_golite062009
kinase activator activity	0.48120280834988	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: