YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|215489524, gi...
Organism:	Escherichia coli O127:H6 str. E2348/69
Length:	243 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|215489524, gi....

Description	E-value	Query Range	Subject Range
gi\|85058322, gi\|... - gi\|85058322\|ref\|YP_454024.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Sodalis glossinidius str....	254.0	[0..1]	[242..1]
RLMB_PHOLL - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Photorhabdus luminescens subsp. laumondii (stra... RLMB_PHOLL - 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB OS=Photorhabdus luminescens subsp. laumondii GN=rl...	253.0	[0..1]	[243..1]
gi\|114770938 - gi\|114770938\|ref\|ZP_01448406.1\| hypothetical protein OM2255_16034 [alpha proteobacterium HTCC2255] gi\|221133725 - gi\|221133725\|ref\|ZP_03560030.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Glaciecola sp. HTCC299... gi\|114770938, gi... - gi\|114770938\|ref\|ZP_01448406.1\| hypothetical protein OM2255_16034 [alpha proteobacterium HTCC2255], ...	253.0	[0..3]	[242..6]
gi\|48859457, gi\|... - gi\|67875040\|ref\|ZP_00504559.1\| RNA methyltransferase TrmH, group 3 [Clostridium thermocellum ATCC 27... gi\|196198671, gi... - gi\|196251913\|ref\|ZP_03150578.1\| RNA methyltransferase, TrmH family, group 3 [Clostridium thermocellu...	253.0	[0..5]	[243..38]
RLMB_ERWCT - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Erwinia carotovora subsp. atroseptica GN=rlmB P... RLMB_PECAS - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Pectobacterium atrosepticum (strain SCRI 1043 /...	252.0	[0..1]	[242..1]
gi\|81247990, gi\|... - gi\|82546579\|ref\|YP_410526.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Shigella boydii Sb227], g...	252.0	[0..1]	[243..1]
gi\|81243586, gi\|... - gi\|82779438\|ref\|YP_405787.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Shigella dysenteriae Sd19...	252.0	[0..1]	[243..1]
gi\|62130448, gi\|... - gi\|62182815\|ref\|YP_219232.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica subsp... gi\|56416160, gi\|... - gi\|56416160\|ref\|YP_153235.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica subsp... gi\|238910527 - gi\|238910527\|ref\|ZP_04654364.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... RLMB_SALTY - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Salmonella typhimurium (strain LT2 / SGSC1412 /... lcl\|NC_016856.1_... - [gene=yjfH] [protein=23S rRNA (guanosine-2'-O-)-methyltransferase] [protein_id=YP_005240682.1] [loca... gi\|197365085, gi... - gi\|197365085\|ref\|YP_002144722.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica s... gi\|204927331, gi... - gi\|204927331\|ref\|ZP_03218533.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica sub... gi\|213428664 - gi\|213428664\|ref\|ZP_03361414.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... gi\|213582911 - gi\|213582911\|ref\|ZP_03364737.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... gi\|194449058, gi... - gi\|194449058\|ref\|YP_002048412.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica s... gi\|194469123, gi... - gi\|194469123\|ref\|ZP_03075107.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica sub... RLMB_SALTY - 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB OS=Salmonella typhimurium GN=rlmB PE=3 SV=1 gi\|194734163, gi... - gi\|194734163\|ref\|YP_002117310.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica su... gi\|197263055, gi... - gi\|197263055\|ref\|ZP_03163129.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica sub... gi\|197287651, gi... - gi\|197287651\|gb\|EDY27042.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... gi\|205336077, gi... - gi\|205336077\|gb\|EDZ22841.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... gi\|205341078, gi... - gi\|205341078\|gb\|EDZ27842.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... gi\|194444737, gi... - gi\|194444737\|ref\|YP_002043624.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica su... gi\|161617640, gi... - gi\|161617640\|ref\|YP_001591605.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica s... gi\|205327237, gi... - gi\|205327237\|gb\|EDZ14001.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... RLMB_SALTY - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Salmonella typhimurium GN=rlmB PE=3 SV=1 gi\|168231407, gi... - gi\|205334208\|gb\|EDZ20972.1\| RNA methyltransferase, TrmH family, group 3 [Salmonella enterica subsp. ... gi\|213852966 - gi\|213852966\|ref\|ZP_03382498.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... gi\|214003352 - gi\|214003352\|ref\|ZP_03414087.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Salmonella enterica su... gi\|224586209, gi... - gi\|224586209\|ref\|YP_002640008.1\| putative tRNA/rRNA methyltransferase [Salmonella enterica subsp. en...	251.0	[0..1]	[243..1]
gi\|88819139, gi\|... - gi\|88858913\|ref\|ZP_01133554.1\| Gm2251 methyltransferase of 23S rRNA [Pseudoalteromonas tunicata D2],...	250.0	[0..2]	[243..3]
RLMB_HAEIN - 23S rRNA (guanosine-2'-O-)-methyltransferase rlmB OS=Haemophilus influenzae GN=rlmB PE=1 SV=1 gi\|148716655, gi... - gi\|148826495\|ref\|YP_001291248.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Haemophilus influenza... gi\|229812452, gi... - gi\|229844738\|ref\|ZP_04464877.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Haemophilus influenzae... gi\|145267883, gi... - gi\|145634717\|ref\|ZP_01790425.1\| hypothetical protein CGSHiAA_03913 [Haemophilus influenzae PittAA], ... gi\|144987136, gi... - gi\|145632229\|ref\|ZP_01787964.1\| hypothetical protein CGSHi3655_07239 [Haemophilus influenzae 3655], ... gi\|229845912, gi... - gi\|229845912\|ref\|ZP_04466024.1\| 23S rRNA (guanosine-2'-O-)-methyltransferase [Haemophilus influenzae... RLMB_HAEIN - 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB OS=Haemophilus influenzae (strain ATCC 51907 / DSM...	250.0	[0..1]	[242..1]

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Predicted Domain #1

Region A:
Residues: [1-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEMIYGIHA VQALLERAPE RFQEVFILKG REDKRLLPLI HALESQGVVI QLANRQYLDE  60
   61 KSDGAVHQGI IARVKPGRQY QENDLPDLIA SLDQPFLLIL DGVTDPHNLG ACLRSADAAG 120
  121 VHAVIVPKDR SAQLNATAKK VACGAAESVP LIRVTNLART MRMLQEENIW IVGTAGEADH 180
  181 TLYQSKMTGR LALVMGAEGE GMRRLTREHC DELISIPMAG SVSSLNVSVA TGICLFEAVR 240
  241 QRS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	67.69897
Match:	1gz0A
Description:	RlmB, C-terminal domain; RlmB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA methyltransferase activity	4.23455016472464	bayes_pls_golite062009
methyltransferase activity	3.59960278169345	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.51722801996622	bayes_pls_golite062009
rRNA methyltransferase activity	3.14976989427746	bayes_pls_golite062009
tRNA methyltransferase activity	2.33123191403389	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.23755555119187	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	2.14623472760939	bayes_pls_golite062009
tRNA (guanine-N1-)-methyltransferase activity	2.0947794364355	bayes_pls_golite062009
transferase activity	1.63934797352054	bayes_pls_golite062009
structural constituent of ribosome	1.0137045454994	bayes_pls_golite062009
catalytic activity	0.797300463760338	bayes_pls_golite062009
rRNA (guanosine-2'-O-)-methyltransferase activity	0.778889412216451	bayes_pls_golite062009
N-methyltransferase activity	0.736216022000293	bayes_pls_golite062009
structural molecule activity	0.694233763389628	bayes_pls_golite062009
binding	0.650146274744039	bayes_pls_golite062009
nucleic acid binding	0.404179021204849	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.319046095835882	bayes_pls_golite062009
	0.16936231012632	bayes_pls_golite062009
snoRNA binding	0.155192244522672	bayes_pls_golite062009
protein binding	0.031057919963412	bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity	6.26422903788337E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: