YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|34811420
Organism:	Escherichia coli
Length:	338 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|34811420.

Description	E-value	Query Range	Subject Range
gi\|75176688 - gi\|75176688\|ref\|ZP_00696816.1\| COG1494: Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase...	530.0	[0..3]	[338..44]
gi\|56130186, gi\|... - gi\|56415929\|ref\|YP_153004.1\| fructose 1,6-bisphosphatase II [Salmonella enterica subsp. enterica ser... gi\|197364856, gi... - gi\|197364856\|ref\|YP_002144493.1\| fructose 1,6-bisphosphatase II [Salmonella enterica subsp. enterica...	527.0	[0..3]	[338..31]
gi\|224585896, gi... - gi\|224585896\|ref\|YP_002639695.1\| fructose 1,6-bisphosphatase II [Salmonella enterica subsp. enterica... gi\|62182544, gi\|... - gi\|62182544\|ref\|YP_218961.1\| fructose 1,6-bisphosphatase II [Salmonella enterica subsp. enterica ser...	527.0	[0..3]	[338..31]
gi\|29139474, gi\|... - gi\|29143838\|ref\|NP_807180.1\| fructose 1,6-bisphosphatase II [Salmonella enterica subsp. enterica ser... gi\|16762350 - gi\|16762350\|ref\|NP_457967.1\| fructose 1,6-bisphosphatase II [Salmonella enterica subsp. enterica ser... gi\|25302397, gi\|... - gi\|25302397\|pir\|\|AH0939 probable glycerol metabolic protein STY3785 [imported] - Salmonella enterica...	527.0	[0..3]	[338..31]
gi\|206566877, gi... - gi\|206577819\|ref\|YP_002235979.1\| fructose-1,6-bisphosphatase, class II [Klebsiella pneumoniae 342], ... gi\|152972507, gi... - gi\|152972507\|ref\|YP_001337653.1\| fructose 1,6-bisphosphatase II [Klebsiella pneumoniae subsp. pneumo... gi\|893384 - gi\|893384\|dbj\|BAA09535.1\| GlpX [Klebsiella aerogenes] gi\|238897103, gi... - gi\|238897103\|ref\|YP_002921849.1\| fructose 1,6-bisphosphatase II [Klebsiella pneumoniae NTUH-K2044], ...	524.0	[0..3]	[338..1]
gi\|254290626, gi... - gi\|254290626\|ref\|YP_003056374.1\| fructose 1,6-bisphosphatase II [Escherichia coli BL21(DE3)], gi\|253... gi\|83586231, gi\|... - gi\|83586231\|ref\|ZP_00924867.1\| COG1494: Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase... gi\|253975776, gi... - gi\|254163875\|ref\|YP_003046983.1\| fructose 1,6-bisphosphatase II [Escherichia coli B str. REL606], gi... gi\|242379461, gi... - gi\|251787188\|ref\|YP_003001492.1\| hypothetical protein B21_03759 [Escherichia coli BL21], gi\|24237946...	524.0	[0..3]	[338..1]
gi\|254795925, gi... - gi\|254795925\|ref\|YP_003080762.1\| fructose 1,6-bisphosphatase II [Escherichia coli O157:H7 str. TW143... gi\|208812907, gi... - gi\|208812907\|ref\|ZP_03254236.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str.... gi\|208808151, gi... - gi\|208808151\|ref\|ZP_03250488.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str.... gi\|195937567 - gi\|195937567\|ref\|ZP_03082949.1\| fructose 1,6-bisphosphatase II [Escherichia coli O157:H7 str. EC4024... gi\|15834104, gi\|... - gi\|15834104\|ref\|NP_312877.1\| fructose 1,6-bisphosphatase II [Escherichia coli O157:H7 str. Sakai], g... gi\|189378041, gi... - gi\|189378041\|gb\|EDU96457.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC5... gi\|217324329, gi... - gi\|217324329\|ref\|ZP_03440413.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str.... gi\|209160245, gi... - gi\|209398845\|ref\|YP_002273443.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str... gi\|208819391, gi... - gi\|208819391\|ref\|ZP_03259711.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str.... gi\|189367915, gi... - gi\|189367915\|gb\|EDU86331.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4... gi\|189357141, gi... - gi\|189357141\|gb\|EDU75560.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4... gi\|209752310, gi... - pir\|\|B86082 unknown function in glycerol metabolism [imported] - Escherichia coli (strain O157:H7, s... gi\|168748779, gi... - gi\|188016816\|gb\|EDU54938.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4... gi\|15804514, gi\|... - gi\|15804514\|ref\|NP_290554.1\| fructose 1,6-bisphosphatase II [Escherichia coli O157:H7 EDL933], gi\|12... gi\|189373300, gi... - gi\|189373300\|gb\|EDU91716.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC8... gi\|15834104, gi\|... - gi\|15834104\|ref\|NP_312877.1\| fructose 1,6-bisphosphatase II [Escherichia coli O157:H7], gi\|13364326\|... gi\|189001541, gi... - gi\|189001541\|gb\|EDU70527.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4... gi\|187769214, gi... - gi\|187769214\|gb\|EDU33058.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4... gi\|189362660, gi... - gi\|189362660\|gb\|EDU81079.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4...	523.0	[0..3]	[338..1]
gi\|75230446, gi\|... - gi\|75230446\|ref\|ZP_00716932.1\| COG1494: Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase...	522.0	[0..3]	[338..1]
GLPX_ECOLI - Fructose-1,6-bisphosphatase class II glpX (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrol... gi\|91075040, gi\|... - gi\|91213466\|ref\|YP_543452.1\| fructose 1,6-bisphosphatase II [Escherichia coli UTI89], gi\|91075040\|gb... gi\|110345853, gi... - gi\|110644261\|ref\|YP_671991.1\| fructose 1,6-bisphosphatase II [Escherichia coli 536], gi\|110345853\|gb... gi\|110617334, gi... - gi\|110807786\|ref\|YP_691306.1\| fructose 1,6-bisphosphatase II [Shigella flexneri 5 str. 8401], gi\|110... gi\|193063924, gi... - gi\|75258092\|ref\|ZP_00729553.1\| COG1494: Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase... gi\|188492619, gi... - gi\|75513889\|ref\|ZP_00736242.1\| COG1494: Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase... gi\|75238368, gi\|... - gi\|75238368\|ref\|ZP_00722367.1\| COG1494: Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase... gi\|190906992, gi... - gi\|75240318\|ref\|ZP_00724258.1\| COG1494: Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase... gi\|227837709, gi... - gi\|227885333\|ref\|ZP_04003138.1\| fructose-bisphosphatase [Escherichia coli 83972], gi\|227837709\|gb\|EE... gi\|89110104, gi\|... - gi\|89110104\|ref\|AP_003884.1\| fructose 1,6-bisphosphatase II [Escherichia coli str. K-12 substr. W311... gi\|226902895, gi... - gi\|237702958\|ref\|ZP_04533439.1\| fructose 1,6-bisphosphatase II [Escherichia sp. 3_2_53FAA], gi\|22690... gi\|238902991, gi... - gi\|238902991\|ref\|YP_002928787.1\| fructose 1,6-bisphosphatase II [Escherichia coli BW2952], gi\|238861... gi\|74314425, gi\|... - gi\|74314425\|ref\|YP_312844.1\| fructose 1,6-bisphosphatase II [Shigella sonnei Ss046], gi\|73857902\|gb\|... gi\|170681842, gi... - gi\|170681842\|ref\|YP_001746310.1\| fructose-1,6-bisphosphatase, class II [Escherichia coli SMS-3-5], g... gi\|81243054, gi\|... - gi\|82778906\|ref\|YP_405255.1\| fructose 1,6-bisphosphatase II [Shigella dysenteriae Sd197], gi\|8124305... gi\|170083395, gi... - gi\|170083395\|ref\|YP_001732715.1\| fructose 1,6-bisphosphatase II [Escherichia coli str. K-12 substr. ... EG11517 - fructose 1,6-bisphosphatase II / Fructose 1,6 bisphosphatase; induced by glycerol, in glpFKX operon,... gi\|75197797, gi\|... - gi\|75197797\|ref\|ZP_00707867.1\| COG1494: Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase... gi\|194414549, gi... - gi\|75211261\|ref\|ZP_00711360.1\| COG1494: Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase... gi\|157155870, gi... - gi\|75188660\|ref\|ZP_00701927.1\| COG1494: Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase... gi\|218434646, gi... - gi\|218707549\|ref\|YP_002415068.1\| fructose 1,6-bisphosphatase II [Escherichia coli UMN026], gi\|218434... gi\|218701372, gi... - gi\|218701372\|ref\|YP_002409001.1\| fructose 1,6-bisphosphatase II [Escherichia coli IAI39], gi\|2183713... GLPX_SHIFL - Fructose-1,6-bisphosphatase class 2 OS=Shigella flexneri GN=glpX PE=3 SV=1 gi\|24115219, gi\|... - gi\|24115219\|ref\|NP_709729.1\| fructose 1,6-bisphosphatase II [Shigella flexneri 2a str. 301], gi\|2405... GLPX_ECOL6 - Fructose-1,6-bisphosphatase class 2 OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) G... gi\|30064782, gi\|... - gi\|30064782\|ref\|NP_838953.1\| fructose 1,6-bisphosphatase II [Shigella flexneri 2a str. 2457T], gi\|30... EG11517 - fructose 1,6-bisphosphatase II / Fructose 1,6 bisphosphatase; induced by glycerol, in glpFKX operon,... gi\|209914664, gi... - gi\|209921405\|ref\|YP_002295489.1\| fructose 1,6-bisphosphatase II [Escherichia coli SE11], gi\|20991466... gi\|187732194, gi... - gi\|187732194\|ref\|YP_001882620.1\| fructose-1,6-bisphosphatase, class II [Shigella boydii CDC 3083-94]... GLPX_ECOL6 - Fructose-1,6-bisphosphatase class 2 OS=Escherichia coli O6 GN=glpX PE=3 SV=1 gi\|218358633, gi... - gi\|218551092\|ref\|YP_002384883.1\| fructose 1,6-bisphosphatase II [Escherichia fergusonii ATCC 35469],... gi\|215267328, gi... - gi\|215489256\|ref\|YP_002331687.1\| fructose 1,6-bisphosphatase II [Escherichia coli O127:H6 str. E2348... gi\|218367761, gi... - gi\|218560992\|ref\|YP_002393905.1\| fructose 1,6-bisphosphatase II [Escherichia coli S88], gi\|218367761... gi\|218363256, gi... - gi\|218556487\|ref\|YP_002389401.1\| fructose 1,6-bisphosphatase II [Escherichia coli IAI1], gi\|21836325... gi\|218354371, gi... - gi\|218697639\|ref\|YP_002405306.1\| fructose 1,6-bisphosphatase II [Escherichia coli 55989], gi\|2183543... gi\|218429773, gi... - gi\|218692209\|ref\|YP_002400421.1\| fructose 1,6-bisphosphatase II [Escherichia coli ED1a], gi\|21842977...	522.0	[0..3]	[338..1]
gi\|21956708, gi\|... - gi\|22123969\|ref\|NP_667392.1\| fructose 1,6-bisphosphatase II [Yersinia pestis KIM], gi\|21956708\|gb\|AA... gi\|45434811, gi\|... - gi\|45439956\|ref\|NP_991495.1\| fructose 1,6-bisphosphatase II [Yersinia pestis biovar Microtus str. 91...	522.0	[0..2]	[338..36]

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Predicted Domain #1

Region A:
Residues: [1-338]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GHMRRELAIE FSRVTESAAL AGYKWLGRGD KNTADGAAVN AMRIMLNQVN IDGTIVIGEG  60
   61 EIDEAPMLYI GEKVGTGRGD AVDIAVDPIE GTRMTAMGQA NALAVLAVGD KGCFLNAPDM 120
  121 YMEKLIVGPG AKGTIDLNLP LADNLRNVAA ALGKPLSELT VTILAKPRHD AVIAEMQQLG 180
  181 VRVFAIPDGD VAASILTCMP DSEVDVLYGI GGAPEGVVSA AVIRALDGDM NGRLLARHDV 240
  241 KGDNEENRRI GEQELARCKA MGIEAGKVLR LGDMARSDNV IFSATGITKG DLLEGISRKG 300
  301 NIATTETLLI RGKSRTIRRI QSIHYLDRKD PEMQVHIL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	150.0
Match:	1ni9A
Description:	Glycerol metabolism protein GlpX
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
fructose 1,6-bisphosphate 1-phosphatase activity	3.7882342162091	bayes_pls_golite062009
catalytic activity	2.50273222033908	bayes_pls_golite062009
carbohydrate phosphatase activity	1.71805011594822	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.12147750685256	bayes_pls_golite062009
phosphatase activity	1.0818856732251	bayes_pls_golite062009
phosphoric ester hydrolase activity	1.05563946024763	bayes_pls_golite062009
fructose-2,6-bisphosphate 2-phosphatase activity	0.807607481385419	bayes_pls_golite062009
inositol or phosphatidylinositol phosphatase activity	0.61593402109125	bayes_pls_golite062009
inositol-1(or 4)-monophosphatase activity	0.224541466803371	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: