YRC Public Data Repository - Protein Structure Prediction

Protein:	MED27_PONAB
Organism:	Pongo abelii
Length:	311 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED27_PONAB.

Description	E-value	Query Range	Subject Range
tr\|G3I9P4\|G3I9P4... - Mediator of RNA polymerase II transcription subunit 27 OS=Cricetulus griseus GN=I79_020298 PE=4 SV=1 MED27_PIG - Mediator of RNA polymerase II transcription subunit 27 OS=Sus scrofa GN=MED27 PE=2 SV=1	597.0	[0..1]	[311..1]
MED27_BOVIN - Mediator of RNA polymerase II transcription subunit 27 OS=Bos taurus GN=MED27 PE=2 SV=1	595.0	[0..1]	[311..1]
gi\|157818903, gi... - gi\|62644833\|ref\|XP_216025.3\| PREDICTED: similar to transcriptional co-activator CRSP8 homolog [Rattu...	595.0	[0..1]	[311..1]
MED27_MOUSE - Mediator of RNA polymerase II transcription subunit 27 OS=Mus musculus GN=Med27 PE=2 SV=2	594.0	[0..1]	[311..1]
gi\|73967722 - gi\|73967722\|ref\|XP_849826.1\| PREDICTED: similar to cofactor required for Sp1 transcriptional activat...	594.0	[0..1]	[311..1]
gi\|109109978 - gi\|109109978\|ref\|XP_001105126.1\| PREDICTED: similar to cofactor required for Sp1 transcriptional act...	593.0	[0..1]	[311..1]
gi\|50757265 - gi\|50757265\|ref\|XP_415455.1\| PREDICTED: similar to cofactor required for Sp1 transcriptional activat...	571.0	[0..1]	[311..33]
gi\|55624172 - gi\|55624172\|ref\|XP_526874.1\| PREDICTED: similar to cofactor required for Sp1 transcriptional activat...	571.0	[0..1]	[311..1]
MED27_XENTR - Mediator of RNA polymerase II transcription subunit 27 OS=Xenopus tropicalis GN=med27 PE=2 SV=1	569.0	[0..1]	[311..1]
MED27_DANRE - Mediator of RNA polymerase II transcription subunit 27 OS=Danio rerio GN=med27 PE=2 SV=1	564.0	[0..1]	[311..1]

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Predicted Domain #1

Region A:
Residues: [1-118]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADVINVSVN LEAFSQAISA IQALRSSVSR VFDCLKDGMR NKETLEGREK AFIAHFQDNL  60
   61 HSVNRDLNEL ERLSNLVGKP SENHPLHNSG LLSLDPVQDK TPLYSQLLQA YKWSNKLQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [119-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YHAGLASGLL NQQSLKRSAN QMGVSAKRRP KAQPTTLVLP PQYVDDVISR IDRMFPEMSI  60
   61 HLSRPNGTSA MLLVTLGKVL KVIVVMRSLF IDRTIVKGYN ENVYTED

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [226-311]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKLDIWSKSN YQVFQKVTDH ATTALLHYQL PQMPDVVVRS FMTWLRSYIK LFQAPCQRCG  60
   61 KFLQDGLPPT WRDFRTLEAF HDTCRQ

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits