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View Structure Prediction Details

Protein: GPMA_ECOLC
Organism: Escherichia coli ATCC 8739
Length: 250 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GPMA_ECOLC.

Description E-value Query
Range
Subject
Range
GPMA_CHLPM - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Chlorobium phaeovibrioides (strain DSM ...
277.0 [0..3] [249..1]
gi|60466735, gi|... - gi|66809133|ref|XP_638289.1| phosphoglycerate mutase [Dictyostelium discoideum AX4], gi|60466735|gb|...
PGAM_DICDI - Probable phosphoglycerate mutase OS=Dictyostelium discoideum GN=gpmA PE=1 SV=1
276.0 [0..4] [250..3]
GPMA_SOLUE - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Solibacter usitatus (strain Ellin6076) ...
276.0 [0..3] [250..1]
gi|56519729 - gi|56519729|emb|CAH78524.1| phosphoglycerate mutase, putative [Plasmodium chabaudi chabaudi]
gi|70942433 - gi|70942433|ref|XP_741383.1| phosphoglycerate mutase [Plasmodium chabaudi chabaudi]
276.0 [0..1] [250..1]
gi|23508399, gi|... - gi|23508399|ref|NP_701068.1| phosphoglycerate mutase, putative [Plasmodium falciparum 3D7], gi|23496...
276.0 [0..1] [250..1]
gi|58177556, gi|... - gi|58177557|pdb|1XQ9|B Chain B, Structure Of Phosphoglycerate Mutase From Plasmodium Falciparum At 2...
275.0 [0..1] [250..9]
GPMA_BDEBA - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Bdellovibrio bacteriovorus (strain ATCC...
GPMA_BDEBA - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Bdellovibrio bacteriovorus GN=gpmA PE=3...
274.0 [0..3] [250..1]
gi|56499296 - gi|56499296|emb|CAH95576.1| phosphoglycerate mutase, putative [Plasmodium berghei]
gi|68073639 - gi|68073639|ref|XP_678734.1| phosphoglycerate mutase [Plasmodium berghei strain ANKA]
273.0 [0..1] [250..1]
GPMA_THETN - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Thermoanaerobacter tengcongensis GN=gpm...
GPMA_CALS4 - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Caldanaerobacter subterraneus subsp. te...
273.0 [0..3] [250..1]
GPMA_CHLPB - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Chlorobium phaeobacteroides (strain BS1...
271.0 [0..3] [249..1]

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Predicted Domain #1
Region A:
Residues: [1-250]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVTKLVLVR HGESQWNKEN RFTGWYDVDL SEKGVSEAKA AGKLLKEEGY SFDFAYTSVL  60
   61 KRAIHTLWNV LDELDQAWLP VEKSWKLNER HYGALQGLNK AETAEKYGDE QVKQWRRGFA 120
  121 VTPPELTKDD ERYPGHDPRY AKLSEKELPL TESLALTIDR VIPYWNETIL PRMKSGERVI 180
  181 IAAHGNSLRA LVKYLDNMSE EEILELNIPT GVPLVYEFDE NFKPLKRYYL GNADEIAAKA 240
  241 AAVANQGKAK 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.69897
Match: 1e58A
Description: Phosphoglycerate mutase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphoglycerate mutase activity 3.38777226675734 bayes_pls_golite062009
phosphofructokinase activity 3.23286891159765 bayes_pls_golite062009
fructose-2,6-bisphosphate 2-phosphatase activity 2.79017097989614 bayes_pls_golite062009
6-phosphofructo-2-kinase activity 2.66778782568695 bayes_pls_golite062009
acid phosphatase activity 2.30852687504184 bayes_pls_golite062009
hydrolase activity 2.03142958239384 bayes_pls_golite062009
carbohydrate kinase activity 1.86382423322759 bayes_pls_golite062009
carbohydrate phosphatase activity 1.56016941506609 bayes_pls_golite062009
binding 1.50412762608586 bayes_pls_golite062009
catalytic activity 1.37714494241232 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.05740895199147 bayes_pls_golite062009
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity 1.02570448989802 bayes_pls_golite062009
phosphatase activity 0.977262057801137 bayes_pls_golite062009
intramolecular transferase activity, phosphotransferases 0.916759493094631 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.780670874345357 bayes_pls_golite062009
isomerase activity 0.275500708652009 bayes_pls_golite062009
protein binding 0.236742803345453 bayes_pls_golite062009
intramolecular transferase activity 0.22072573159348 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.116796724149401 bayes_pls_golite062009

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