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View Structure Prediction Details

Protein: FGF7_PONAB
Organism: Pongo abelii
Length: 194 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FGF7_PONAB.

Description E-value Query
Range		 Subject
Range
gi|60829861 - gi|60829861|gb|AAX36897.1| fibroblast growth factor 7 [synthetic construct]
 9.0E-74 [1..194] [1..194]
FGF7_SHEEP - Fibroblast growth factor 7 OS=Ovis aries GN=FGF7 PE=2 SV=1
 4.0E-73 [1..194] [1..194]
FGF7_CEREL - Fibroblast growth factor 7 OS=Cervus elaphus GN=FGF7 PE=2 SV=1
gi|119902623 - gi|119902623|ref|XP_874109.2| PREDICTED: similar to keratinocyte growth factor FGF-7 [Bos taurus]
 6.0E-73 [1..194] [1..194]
FGF7_CANLF - Fibroblast growth factor 7 OS=Canis lupus familiaris GN=FGF7 PE=2 SV=1
 1.0E-72 [1..194] [1..194]
FGF7_PIG - Fibroblast growth factor 7 OS=Sus scrofa GN=FGF7 PE=2 SV=1
 6.0E-71 [1..194] [1..194]
gi|16226033 - gi|16226033|gb|AAL16059.1| keratinocyte growth factor FGF-7 [Mustela vison]
gi|16226033|gb|A... - keratinocyte growth factor FGF-7 [Mustela vison]
 8.0E-67 [1..184] [1..184]
FGF7_MOUSE - Fibroblast growth factor 7 OS=Mus musculus GN=Fgf7 PE=2 SV=1
 6.0E-66 [1..194] [1..194]
gi|57158201, gi|... - gi|60302702|ref|NP_001012543.1| fibroblast growth factor 7 (keratinocyte growth factor) [Gallus gall...
 3.0E-65 [1..194] [1..194]
gi|7438522, gi|2... - pir||S26049 fibroblast growth factor 7 precursor - rat, gi|228381|prf||1803329A keratinocyte growth...
 1.0E-64 [1..194] [1..194]

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Predicted Domain #1
Region A:
Residues: [1-194] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHKWILTWIL PTLLYRSCFH IICLVGTISL ACNDMTPEQM ATNVNCSSPE RHTRSYDYME  60
   61 GGDIRVRRLF CRTQWYLRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA 120
  121 MNKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVALNQK GIPVRGKKTK 180
  181 KEQKTAHFLP MAIT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.154902
Match: 1qqkA
Description: Keratinocyte growth factor, FGF7
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
fibroblast growth factor receptor binding 5.68976822724664 bayes_pls_golite062009
growth factor activity 5.6790632853895 bayes_pls_golite062009
receptor binding 4.8109037277027 bayes_pls_golite062009
cytokine activity 3.72907359340826 bayes_pls_golite062009
protein binding 2.99442649109752 bayes_pls_golite062009
binding 2.90110516688922 bayes_pls_golite062009
type 2 fibroblast growth factor receptor binding 1.96512066847854 bayes_pls_golite062009
heparin binding 1.71092312487163 bayes_pls_golite062009
signal transducer activity 1.24692031673405 bayes_pls_golite062009
molecular transducer activity 1.24692031673405 bayes_pls_golite062009
glycosaminoglycan binding 1.04794819242244 bayes_pls_golite062009
polysaccharide binding 0.55309369051712 bayes_pls_golite062009
pattern binding 0.323275442862789 bayes_pls_golite062009
nerve growth factor receptor binding 0.308245352535379 bayes_pls_golite062009
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