YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|31615321
Organism:	Homo sapiens
Length:	173 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|31615321.

Description	E-value	Query Range	Subject Range
gi\|149045973, gi... - gi\|149045973\|gb\|EDL98866.1\| rCG22235 [Rattus norvegicus], gi\|109487201\|ref\|XP_001066957.1\| PREDICTED...	254.0	[0..2]	[172..181]
gi\|74005660 - gi\|74005660\|ref\|XP_545619.2\| PREDICTED: similar to Gamma crystallin A (Gamma crystallin 1-1) [Canis ...	253.0	[0..1]	[172..175]
gi\|114583007 - gi\|114583007\|ref\|XP_516055.2\| PREDICTED: similar to gammaD-crystallin [Pan troglodytes]	246.0	[0..1]	[173..84]
gi\|76679190 - gi\|76679190\|ref\|XP_584674.2\| PREDICTED: similar to Gamma crystallin A (Gamma crystallin 1-1), partia...	244.0	[0..1]	[172..57]
gi\|109100825 - gi\|109100825\|ref\|XP_001100337.1\| PREDICTED: similar to crystallin, gamma D [Macaca mulatta]	243.0	[0..1]	[173..40]

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Predicted Domain #1

Region A:
Residues: [1-173]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKITLYEDRG FQGRHYECSS DHPNLQPYLS RCNSARVDSG CWMLYEQPNY SGLQYFLHRG  60
   61 DYADHQQWMG LSDSVRSCRL IPHSGSHRIR LYEREDYRGQ MIEFTEDCSC LQDRFRFNEI 120
  121 HSLNVLEGSW VLYELSNYRG RQYLLMPGDY RRYQDWGATN ARVGSLRRVI DFS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.30103
Match:	1hk0X
Description:	gamma-Crystallin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
structural constituent of eye lens	3.95613127220698	bayes_pls_golite062009
binding	1.49962891213419	bayes_pls_golite062009
protein binding	0.439215717175215	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: