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View Structure Prediction Details

Protein: gi|7494462, gi|1...
Organism: Plasmodium vivax
Length: 1087 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7494462, gi|1....

Description E-value Query
Range
Subject
Range
gi|7494463, gi|1... - pir||T30846 serine-repeat antigen 5 precursor - Plasmodium vivax, gi|1381094|gb|AAB02634.1| V-SERA ...
866.0 [0..1] [1087..1]
gi|23593286, gi|... - gi|23593286|ref|NP_472999.2| cysteine protease, putative [Plasmodium falciparum 3D7], gi|23503374|gb...
819.0 [0..29] [1087..64]
gi|56501281 - gi|56501281|emb|CAH99257.1| cysteine protease, putative [Plasmodium berghei]
gi|68076879 - gi|68076879|ref|XP_680359.1| cysteine protease [Plasmodium berghei strain ANKA]
724.0 [0..153] [1087..1]
gi|83315601 - gi|83315601|ref|XP_730864.1| cysteine protease [Plasmodium yoelii yoelii str. 17XNL]
gi|23490719 - gi|23490719|gb|EAA22429.1| Papain family cysteine protease, putative [Plasmodium yoelii yoelii]
709.0 [0..154] [1087..189]

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Predicted Domain #1
Region A:
Residues: [1-174]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSRLCALLI LYMLLNGHSV KCTAAVGQGQ GTGVSTDQGV SSQHTANSAG QGIGSSTGST  60
   61 GVPQSRPQSG GGDTGTQGGQ QDRASGTSAT HVPVVPQNGH VQSNPPPSTS SGGPNGGGGA 120
  121 SITQNVQQAN LQAGSDTQVA ATPSESFTNP IQVKASLLRD QKGLKITGPC KSYF

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [175-393]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVYLVPYLYL NVNAKESEIE MDPMFMKVDD KIKFEKEKHL LNNICEDNKT FKLVVYMYEG  60
   61 ELTIKWKVYP PKGETSSDKT LDIRKYKMKD IGQPITSMQV VVMSELNKTI YMESKNFAVM 120
  121 NQIPEKCDAI ANECFLSGVL DVQKCYHCTL LLQKKENAEE CFKFVSPTIK NRFEDIQTKG 180
  181 EDEENPNVVE LEETIDLLLN KIYKNGEGES NEVDQLAII

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [394-772]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSSFQSDLLK YCSLMKEVDT SGSLDNHQLG DAEDVFANLT HLLQSNSDHD VPSLKNKLKS  60
   61 PAICLKNVGH WVGSKTGLVL PTLEYSTSQD NAESFDEGEE DTSNSTTTQS ADVHPLNVSD 120
  121 KLFCNDEYCD RAKDSSSCIA KIEAGDQGDC STSWLFASKV HLEAIKCMKG HDHVASSALY 180
  181 VANCSGKEAN DKCHAASNPL EFLNTLEETK FLAAESDLPY SYKAVNNACP EPKSHWKNLW 240
  241 ENVKLLDPTN EPNSVSTKGY TAYQSDHFKG NMDAFIKLVK SEVMKKGSAI AYVKAQGALS 300
  301 YDLNGKKVQS LCGGETPDLA VNIVGYGNYI TAEGQKKSYW LLQNSWGKHW GDDGNFKVDM 360
  361 HGPDHCQNNF IHTAAVFNL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 103.0
Match: 1cs8A
Description: (Pro)cathepsin L
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.529663942126259 bayes_pls_golite062009
hydrolase activity 0.16837900182603 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [773-1087]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVPVVAPAPS SDPEINDYYM KNSPDFFSNF YFNKYEAEKA NGLGEEKGPV NNSVLYGQSG  60
   61 EETSALPASV GDQSGKVVAQ TAEGLGAQQG SGGGLGAAAG PTGQEGVGVA APGGRGTGGE 120
  121 AIAAAAVVVV GGGGSGSAGE RGTGVGVAPG VGAAGRSVGE GQQLPAGAAS PGTGTQHVGG 180
  181 SVSGGTNSGN GATGNSGPNT QRGQVSQTVN EAAPSTVEKP KSIDSTGVIS EGITGVFHFL 240
  241 KNVKKGKVSS NFVTYDNTKA IGDKACSRVQ SSDVDKLDDC VKFCEANWNE CKGKVSPGYC 300
  301 LTKKKGNNDC FFCFV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 31.39794
Match: 1y0fA
Description: No description for 1y0fA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle