YRC Public Data Repository - Protein Structure Prediction

Protein:	TYOBP_BOVIN
Organism:	Bos taurus
Length:	108 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TYOBP_BOVIN.

Description	E-value	Query Range	Subject Range
gi\|16945316, gi\|... - gi\|41386800\|ref\|NP_777052.1\| TYRO protein tyrosine kinase binding protein [Bos taurus], gi\|16945316\|...	147.0	[0..1]	[108..1]
gi\|73948444 - gi\|73948444\|ref\|XP_533687.2\| PREDICTED: similar to TYRO protein tyrosine kinase binding protein isof...	138.0	[0..1]	[108..66]
gi\|55741821 - ref\|NP_999367.1\| immunoreceptor DAP12 [Sus scrofa] TYOBP_PIG - TYRO protein tyrosine kinase-binding protein OS=Sus scrofa GN=TYROBP PE=2 SV=1	137.0	[0..1]	[108..1]
TYOBP_MOUSE - TYRO protein tyrosine kinase-binding protein OS=Mus musculus GN=Tyrobp PE=1 SV=1	136.0	[0..1]	[108..1]
gi\|38158005, gi\|... - gi\|5706450\|emb\|CAB52288.1\| killer activating receptor associated protein, isoform b [Homo sapiens], ...	132.0	[0..1]	[108..1]
TYOBP_PANTR - TYRO protein tyrosine kinase-binding protein OS=Pan troglodytes GN=TYROBP PE=3 SV=1	130.0	[0..1]	[108..1]
TYOBP_RAT - TYRO protein tyrosine kinase-binding protein OS=Rattus norvegicus GN=Tyrobp PE=3 SV=1	130.0	[0..1]	[108..1]
TYOBP_MACMU - TYRO protein tyrosine kinase-binding protein OS=Macaca mulatta GN=TYROBP PE=3 SV=1	129.0	[0..1]	[108..1]

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Predicted Domain #1

Region A:
Residues: [1-108]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGLRPSDRL LSLLLTVGGL SLVLAQSECN CSSVSPGVLA GIVLGDLMLT LLIALAVYYL  60
   61 GRLVPRGRGA TEVTRKQHIP ETESPYQELQ GQRTDVYSDL NTQRPYYK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.330	a.1.1	Globin-like
View	Download	0.362	a.45.1	Glutathione S-transferase (GST), C-terminal domain
View	Download	0.322	a.142.1	PTS-regulatory domain, PRD
View	Download	0.303	a.167.1	Porin chaperone SurA, peptide-binding domain
View	Download	0.327	a.1.1	Globin-like

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.0450544645706373	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: