YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|55670886, gi\|...
Organism:	Pyrococcus furiosus
Length:	215 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|55670886, gi|....

Description	E-value	Query Range	Subject Range
THIE_PYRFU - Thiamine-phosphate synthase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) G... THIE_PYRFU - Thiamine-phosphate pyrophosphorylase OS=Pyrococcus furiosus GN=thiE PE=1 SV=1	191.0	[0..10]	[215..2]
THIE_PYRAB - Thiamine-phosphate pyrophosphorylase OS=Pyrococcus abyssi GN=thiE PE=3 SV=1 THIE_PYRAB - Thiamine-phosphate synthase OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=thiE PE=3 SV=1	188.0	[0..12]	[215..4]
THIE_PYRHO - Thiamine-phosphate synthase OS=Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NB... THIE_PYRHO - Probable thiamine-phosphate pyrophosphorylase OS=Pyrococcus horikoshii GN=thiE PE=3 SV=2	187.0	[0..12]	[215..4]
gi\|120326270, gi... - gi\|77953959\|ref\|ZP_00818361.1\| Ribulose-phosphate 3-epimerase [Marinobacter aquaeolei VT8], gi\|77867...	180.0	[0..15]	[214..1]
gi\|12722019, gi\|... - gi\|15603484\|ref\|NP_246558.1\| ribulose-phosphate 3-epimerase [Pasteurella multocida subsp. multocida ...	180.0	[0..12]	[210..13]
THIE_SYNY3 - Thiamine-phosphate synthase OS=Synechocystis sp. (strain PCC 6803 / Kazusa) GN=thiE PE=3 SV=1 gi\|7427960 - pir\|\|S74943 thiamine-phosphate diphosphorylase (EC 2.5.1.3) - Synechocystis sp. (strain PCC 6803) THIE_SYNY3 - Thiamine-phosphate pyrophosphorylase OS=Synechocystis sp. (strain ATCC 27184 / PCC 6803 / N-1) GN=th...	179.0	[0..10]	[212..138]
gi\|23130348 - gi\|23130348\|ref\|ZP_00112165.1\| COG0352: Thiamine monophosphate synthase [Nostoc punctiforme PCC 7310...	178.0	[0..16]	[212..170]
gi\|68249166, gi\|... - gi\|68249166\|ref\|YP_248278.1\| ribulose-phosphate 3-epimerase [Haemophilus influenzae 86-028NP], gi\|68...	178.0	[0..9]	[213..5]
gi\|22127808, gi\|... - gi\|22127808\|ref\|NP_671231.1\| ribulose-phosphate 3-epimerase [Yersinia pestis KIM], gi\|21960939\|gb\|AA... gi\|167419005, gi... - gi\|167419005\|ref\|ZP_02310758.1\| ribulose-phosphate 3-epimerase [Yersinia pestis biovar Orientalis st... gi\|45434874, gi\|... - gi\|45440019\|ref\|NP_991558.1\| ribulose-phosphate 3-epimerase [Yersinia pestis biovar Microtus str. 91... gi\|165936169, gi... - gi\|165936169\|ref\|ZP_02224738.1\| ribulose-phosphate 3-epimerase [Yersinia pestis biovar Orientalis st... gi\|167399079, gi... - gi\|167399079\|ref\|ZP_02304603.1\| ribulose-phosphate 3-epimerase [Yersinia pestis biovar Antiqua str. ... gi\|165928023, gi... - gi\|165928023\|ref\|ZP_02223855.1\| ribulose-phosphate 3-epimerase [Yersinia pestis biovar Orientalis st...	178.0	[0..11]	[210..1]
THIE_METMP - Thiamine-phosphate synthase OS=Methanococcus maripaludis (strain S2 / LL) GN=thiE PE=3 SV=1 THIE_METMP - Thiamine-phosphate pyrophosphorylase OS=Methanococcus maripaludis GN=thiE PE=3 SV=1	177.0	[0..10]	[213..2]

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Predicted Domain #1

Region A:
Residues: [1-215]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AHHHHHHGSN LRNKLKLYVI TDRRLKPEVE SVREALEGGA TAIQMRIKNA PTREMYEIGK  60
   61 TLRQLTREYD ALFFVDDRVD VALAVDADGV QLGPEDMPIE VAKEIAPNLI IGASVYSLEE 120
  121 ALEAEKKGAD YLGAGSVFPT KTKEDARVIG LEGLRKIVES VKIPVVAIGG INKDNAREVL 180
  181 KTGVDGIAVI SAVMGAEDVR KATEELRKIV EEVLG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.045757
Match:	1xi3A
Description:	Thiamine phosphate pyrophosphorylase from Pyrococcus furiosus Pfu-1255191-001
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
thiamin-phosphate diphosphorylase activity	6.04450222340788	bayes_pls_golite062009
catalytic activity	2.31352397210218	bayes_pls_golite062009
phosphomethylpyrimidine kinase activity	2.16632642989285	bayes_pls_golite062009
transferase activity, transferring alkyl or aryl (other than methyl) groups	1.16976945211093	bayes_pls_golite062009
transferase activity	1.16478613213801	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	0.63318404518052	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: