YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|55670567, gi\|...
Organism:	Homo sapiens
Length:	276 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|55670567, gi|....

Description	E-value	Query Range	Subject Range
gi\|73948314 - gi\|73948314\|ref\|XP_855312.1\| PREDICTED: similar to inositol 1,4,5-trisphosphate 3-kinase C [Canis fa...	338.0	[0..3]	[275..349]
gi\|20072243 - gi\|20072243\|gb\|AAH26331.1\| Inositol 1,4,5-trisphosphate 3-kinase A [Homo sapiens]	338.0	[0..2]	[276..187]
gi\|60654369 - gi\|60654369\|gb\|AAX29875.1\| inositol 145-trisphosphate 3-kinase A [synthetic construct]	338.0	[0..2]	[276..187]
gi\|114656470 - gi\|114656470\|ref\|XP_001149577.1\| PREDICTED: 1D-myo-inositol-trisphosphate 3-kinase A [Pan troglodyte...	338.0	[0..2]	[276..127]
gi\|50756151 - gi\|50756151\|ref\|XP_415039.1\| PREDICTED: similar to Inositol-trisphosphate 3-kinase B (Inositol 1,4,5...	337.0	[0..3]	[275..516]
gi\|109080785 - gi\|109080785\|ref\|XP_001099176.1\| PREDICTED: 1D-myo-inositol-trisphosphate 3-kinase A [Macaca mulatta...	336.0	[0..2]	[276..371]
gi\|76627394, gi\|... - gi\|76627394\|ref\|XP_874147.1\| PREDICTED: similar to inositol 1,4,5-triphosphate 3-kinase isoform 2 [B...	336.0	[0..2]	[276..187]

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Predicted Domain #1

Region A:
Residues: [1-276]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 XSWVQLAGHT GSFKAAGTSG LILKRCSEPE RYCLARLXAD ALRGCVPAFH GVVERDGESY  60
   61 LQLQDLLDGF DGPCVLDCKX GVRTYLEEEL TKARERPKLR KDXYKKXLAV DPEAPTEEEH 120
  121 AQRAVTKPRY XQWREGISSS TTLGFRIEGI KKADGSCSTD FKTTRSREQV LRVFEEFVQG 180
  181 DEEVLRRYLN RLQQIRDTLE VSEFFRRHEV IGSSLLFVHD HCHRAGVWLI DFGKTTPLPD 240
  241 GQILDHRRPW EEGNREDGYL LGLDNLIGIL ASLAER

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	91.69897
Match:	1w2fA
Description:	Human Inositol (1,4,5)-trisphosphate 3-kinase substituted with selenomethionine
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.3478684630282	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: