YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|79382641, gi\|...
Organism:	Arabidopsis thaliana
Length:	642 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|79382641, gi|....

Description	E-value	Query Range	Subject Range
HMDH1_ARATH - 3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 OS=Arabidopsis thaliana GN=HMG1 PE=1 SV=1	788.0	[0..51]	[642..1]
HMDH3_SOLTU - 3-hydroxy-3-methylglutaryl-coenzyme A reductase 3 OS=Solanum tuberosum GN=HMG3 PE=2 SV=1	761.0	[0..51]	[633..1]
gi\|18000042 - gi\|18000042\|gb\|AAL54878.1\|AF004232_1 hydroxy-methyl-glutaryl-coenzyme A reductase [Nicotiana tabacum...	759.0	[0..51]	[636..1]
HMDH_NICSY - 3-hydroxy-3-methylglutaryl-coenzyme A reductase OS=Nicotiana sylvestris GN=HMGR PE=2 SV=1	756.0	[0..51]	[636..1]
gi\|29468498 - gi\|29468498\|gb\|AAO85554.1\| 3-hydroxy-3-methylglutaryl-CoA reductase [Nicotiana attenuata]	755.0	[0..51]	[636..1]
gi\|2246450 - gi\|2246450\|gb\|AAB62581.1\| 3-hydroxy-3-methylglutaryl CoA reductase 2 [Lycopersicon esculentum]	754.0	[0..51]	[636..1]
HMDH2_CAPAN - 3-hydroxy-3-methylglutaryl-coenzyme A reductase 2 OS=Capsicum annuum GN=HMGR2 PE=2 SV=1	749.0	[0..51]	[636..1]

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Predicted Domain #1

Region A:
Residues: [1-63]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKKQAGPQQ TCEFVSYKTL LISPSHLSRH LTTSLLSPLS PPWRDYSFPP MDLRRRPPKP  60
   61 PVT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [64-141]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NNNNSNGSFR SYQPRTSDDD HRRRATTIAP PPKASDALPL PLYLTNAVFF TLFFSVAYYL  60
   61 LHRWRDKIRY NTPLHVVT

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [142-642]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ITELGAIIAL IASFIYLLGF FGIDFVQSFI SRASGDAWDL ADTIDDDDHR LVTCSPPTPI  60
   61 VSVAKLPNPE PIVTESLPEE DEEIVKSVID GVIPSYSLES RLGDCKRAAS IRREALQRVT 120
  121 GRSIEGLPLD GFDYESILGQ CCEMPVGYIQ IPVGIAGPLL LDGYEYSVPM ATTEGCLVAS 180
  181 TNRGCKAMFI SGGATSTVLK DGMTRAPVVR FASARRASEL KFFLENPENF DTLAVVFNRS 240
  241 SRFARLQSVK CTIAGKNAYV RFCCSTGDAM GMNMVSKGVQ NVLEYLTDDF PDMDVIGISG 300
  301 NFCSDKKPAA VNWIEGRGKS VVCEAVIRGE IVNKVLKTSV AALVELNMLK NLAGSAVAGS 360
  361 LGGFNAHASN IVSAVFIATG QDPAQNVESS QCITMMEAIN DGKDIHISVT MPSIEVGTVG 420
  421 GGTQLASQSA CLNLLGVKGA STESPGMNAR RLATIVAGAV LAGELSLMSA IAAGQLVRSH 480
  481 MKYNRSSRDI SGATTTTTTT T

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	164.0
Match:	1dq8A
Description:	NAD-binding domain of HMG-CoA reductase; Substrate-binding domain of HMG-CoA reductase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.2	NCBI nr	03/2009
PSI-BLAST	2.2.22	FFAS	ffas03
PDB	10/2008	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits