YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|2554754, gi\|2...
Organism:	Homo sapiens
Length:	112 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|2554754, gi|2....

Description	E-value	Query Range	Subject Range
gi\|148726500, gi... - gi\|47086483\|ref\|NP_997946.1\| Yes-related kinase [Danio rerio], gi\|27372075\|gb\|AAN87886.1\| Yes-relaye...	133.0	[0..2]	[112..130]
gi\|51950203, gi\|... - gi\|56118779\|ref\|NP_001008186.1\| v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 [Xenopus (Siluran...	132.0	[0..2]	[112..142]
gi\|148233834, gi... - gi\|71681264\|gb\|AAI00229.1\| MGC115231 protein [Xenopus laevis], gi\|148233834\|ref\|NP_001089660.1\| hypo...	132.0	[0..2]	[112..142]
gi\|223627 - gi\|223627\|prf\|\|0903255A protein v-src	132.0	[0..2]	[112..384]
gi\|66797 - gi\|66797\|pir\|\|TVFVG9 protein-tyrosine kinase (EC 2.7.1.112) yes - avian sarcoma virus Y73	131.0	[0..2]	[112..138]
gi\|223452 - gi\|223452\|prf\|\|0806225A genome Y73	131.0	[0..2]	[112..422]
YES_CHICK - Tyrosine-protein kinase Yes OS=Gallus gallus GN=YES1 PE=1 SV=3	131.0	[0..2]	[112..146]

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Predicted Domain #1

Region A:
Residues: [1-112]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSPIPHHDEK TWNVGSSNRN KAENLLRGKR DGTFLVRESS KQGCYACSVV VDGEVKHCVI  60
   61 NKTATGYGFA EPYNLYSSLK ELVLHYQHTS LVQHNDSLNV TLAYPVYAQQ RR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.0
Match:	1h9oA
Description:	Phosphatidylinositol 3-kinase, p85-alpha subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.434026084000615	bayes_pls_golite062009
protein binding	0.31534665043077	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: