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View Structure Prediction Details

Protein: gi|13786858
Organism: Homo sapiens
Length: 181 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|13786858.

Description E-value Query
Range		 Subject
Range
gi|2136608 - pir||I46621 prointerleukin 6 - pig
gi|164625, gi|11... - gi|47523852|ref|NP_999564.1| interleukin 6 [Sus scrofa], gi|198033679|emb|CAM58482.1| interleukin 6 ...
 265.0 [0..6] [171..47]
IL6_DELLE - Interleukin-6 OS=Delphinapterus leucas GN=IL6 PE=2 SV=1
 258.0 [0..6] [170..42]
IL6_CAMBA - Interleukin-6 OS=Camelus bactrianus GN=IL6 PE=2 SV=1
 256.0 [0..3] [171..43]
IL6_ORCOR - Interleukin-6 (Fragment) OS=Orcinus orca GN=IL6 PE=2 SV=1
 256.0 [0..6] [170..39]
gi|9247084 - gi|9247084|gb|AAF86275.1| interleukin-6 [Canis familiaris]
 254.0 [0..5] [171..41]
IL6_LAMGL - Interleukin-6 OS=Lama glama GN=IL6 PE=2 SV=1
 253.0 [0..4] [171..44]
gi|457438 - gi|457438|dbj|BAA02507.1| interleukin 6 [Felis catus]
IL6_FELCA - Interleukin-6 OS=Felis catus GN=IL6 PE=2 SV=1
 251.0 [0..5] [171..42]

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Predicted Domain #1
Region A:
Residues: [1-181] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPDAPEFEKD LLIQRLNWML WVIDECFRDL CYRTGICKGI LEPAAIFHLK LPAINDTDHC  60
   61 GLIGFNETSC LKKLADGFFE FEVLFKFLTT EFGKSVINVD VMELLTKTLG WDIQEELNKL 120
  121 TKTHYSPPKF DRGLLGRLQG LKYWVRHFAS FYVLSAMEKF AGQAVRVLDS IPDVTPDVHD 180
  181 K

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Detection Method: PSI-BLAST
Confidence: 51.0
Match: 1i1rB
Description: Interleukin-6
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.690795394803185 bayes_pls_golite062009
protein binding 0.6394379925035 bayes_pls_golite062009
receptor binding 0.394045730859399 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle