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View Structure Prediction Details

Protein: gi|7245491
Organism: Homo sapiens
Length: 207 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7245491.

Description E-value Query
Range
Subject
Range
gi|73954335 - gi|73954335|ref|XP_536502.2| PREDICTED: similar to Prolactin receptor precursor (PRL-R) [Canis famil...
169.0 [0..4] [202..83]
gi|49274649, gi|... - gi|49274649|ref|NP_001001868.1| prolactin receptor [Sus scrofa], gi|34596483|gb|AAQ76843.1| prolacti...
167.0 [0..4] [201..31]
PRLR_BOVIN - Prolactin receptor OS=Bos taurus GN=PRLR PE=1 SV=1
167.0 [0..2] [203..25]
PRLR_SHEEP - Prolactin receptor OS=Ovis aries GN=PRLR PE=2 SV=1
166.0 [0..2] [203..25]
PRLR_RABIT - Prolactin receptor OS=Oryctolagus cuniculus GN=PRLR PE=1 SV=1
164.0 [0..7] [201..34]
PRLR_CEREL - Prolactin receptor OS=Cervus elaphus GN=PRLR PE=2 SV=1
164.0 [0..4] [203..31]

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Predicted Domain #1
Region A:
Residues: [1-207]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FKVLQEPTCV SDYMSISTCE WKMNGPTNCS TELRLLYQLV FLLSEAHTCI PENNGGAGCV  60
   61 CHLLMDDVVS ADNYTLDLWA GQQLLWKGSF KPSEHVKPRA PGNLTVHTNV SDTLLLTWSN 120
  121 PYPPDNYLYN HLTYAVNIWS ENDPADFRIY NVTYLEPSLR IAASTLKSGI SYRARVRAWA 180
  181 QAYNTTWSEW SPSTKWHNSY REPFEQH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 36.09691
Match: 1iarB
Description: Interleukin-4 receptor alpha chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.431491932986215 bayes_pls_golite062009
protein binding 0.3642499004435 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle