YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|4139887, gi\|4...
Organism:	Mycobacterium tuberculosis
Length:	284 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|4139887, gi|4....

Description	E-value	Query Range	Subject Range
gi\|91228624, gi\|... - gi\|91228624\|ref\|ZP_01262541.1\| nicotinate-nucleotide pyrophosphorylase [Vibrio alginolyticus 12G01],...	287.0	[0..2]	[283..14]
gi\|90438546, gi\|... - gi\|90580244\|ref\|ZP_01236051.1\| nicotinate-nucleotide pyrophosphorylase [Vibrio angustum S14], gi\|904...	287.0	[0..2]	[283..14]
gi\|54310287, gi\|... - gi\|54310287\|ref\|YP_131307.1\| quinolinate phosphoribosyltransferase [Photobacterium profundum SS9], g...	286.0	[0..2]	[283..34]
gi\|89050087, gi\|... - gi\|89074151\|ref\|ZP_01160650.1\| nicotinate-nucleotide pyrophosphorylase [Photobacterium sp. SKA34], g...	284.0	[0..2]	[283..14]
gi\|37199711, gi\|... - gi\|37680961\|ref\|NP_935570.1\| quinolinate phosphoribosyltransferase [Vibrio vulnificus YJ016], gi\|371...	284.0	[0..2]	[283..26]
gi\|28899296, gi\|... - gi\|28899296\|ref\|NP_798901.1\| quinolinate phosphoribosyltransferase [Vibrio parahaemolyticus RIMD 221... gi\|28807520 - gi\|28807520\|dbj\|BAC60785.1\| NadC [Vibrio parahaemolyticus RIMD 2210633]	283.0	[0..2]	[283..14]
gi\|16930777 - gi\|16930777\|gb\|AAL32048.1\|AF439854_1 NadC [Vibrio vulnificus]	283.0	[0..2]	[283..14]
gi\|27361137, gi\|... - gi\|27364991\|ref\|NP_760519.1\| quinolinate phosphoribosyltransferase [Vibrio vulnificus CMCP6], gi\|273...	282.0	[0..2]	[283..14]
gi\|77995232, gi\|... - gi\|78043117\|ref\|YP_361169.1\| nicotinate-nucleotide pyrophosphorylase [Carboxydothermus hydrogenoform...	281.0	[0..6]	[284..2]
gi\|59480892, gi\|... - gi\|59712791\|ref\|YP_205567.1\| quinolinate phosphoribosyltransferase [Vibrio fischeri ES114], gi\|59480...	280.0	[0..2]	[283..18]

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Predicted Domain #1

Region A:
Residues: [1-284]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLSDWELAAA RAAIARGLDE DLRYGPDVTT LATVPASATT TASLVTREAG VVAGLDVALL  60
   61 TLNEVLGTNG YRVLDRVEDG ARVPPGEALM TLEAQTRGLL TAERTMLNLV GHLSGIATAT 120
  121 AAWVDAVRGT KAKIRDTRKT LPGLRALQKY AVRTGGGVNH RLGLGDAALI KDNHVAAAGS 180
  181 VVDALRAVRN AAPDLPCEVE VDSLEQLDAV LPEKPELILL DNFAVWQTQT AVQRRDSRAP 240
  241 TVMLESSGGL SLQTAATYAE TGVDYLAVGA LTHSVRVLDI GLDM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.0
Match:	1qpnA
Description:	Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain; Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nicotinate-nucleotide diphosphorylase (carboxylating) activity	5.06171490122183	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	3.41342374351311	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.09481377885324	bayes_pls_golite062009
nicotinate phosphoribosyltransferase activity	2.88703411089498	bayes_pls_golite062009
catalytic activity	2.59603106157451	bayes_pls_golite062009
transferase activity	1.91642626258277	bayes_pls_golite062009
binding	1.13767396490743	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: