YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|6137576, gi\|1...
Organism:	Homo sapiens
Length:	97 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|6137576, gi|1....

Description	E-value	Query Range	Subject Range
gi\|68270852, gi\|... - gi\|68270852\|gb\|AAY88917.1\| caspase-9 [Oncorhynchus mykiss], gi\|185135856\|ref\|NP_001118119.1\| caspase...	118.0	[0..1]	[96..1]
gi\|47222798 - gi\|47222798\|emb\|CAG01765.1\| unnamed protein product [Tetraodon nigroviridis]	116.0	[0..1]	[95..1]
gi\|66910436 - gi\|66910436\|gb\|AAH97103.1\| Zgc:101776 protein [Danio rerio]	115.0	[0..1]	[96..1]
gi\|76618984 - gi\|76618984\|ref\|XP_886305.1\| PREDICTED: similar to Apoptotic protease activating factor 1 (Apaf-1) i...	114.0	[0..1]	[97..1]
gi\|148233858, gi... - gi\|7619908\|dbj\|BAA94750.1\| caspase-9 [Xenopus laevis], gi\|148233858\|ref\|NP_001079035.1\| caspase-9 [X...	113.0	[0..1]	[94..1]
gi\|85541537, gi\|... - gi\|85541539\|gb\|ABC70999.1\| caspase-9 [Dicentrarchus labrax], gi\|85541537\|gb\|ABC70998.1\| caspase-9 [D...	110.0	[0..1]	[95..1]
gi\|60360324 - gi\|60360324\|dbj\|BAD90406.1\| mKIAA0413 protein [Mus musculus]	107.0	[0..1]	[97..3]

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Predicted Domain #1

Region A:
Residues: [1-97]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAKARNCLL QHREALEKDI KTSYIMDHMI SDGFLTISEE EKVRNEPTQQ QRAAMLIKMI  60
   61 LKKDNDSYVS FYNALLHEGY KDLAALLHDG IPVVSSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.0
Match:	1cwwA
Description:	Apoptotic protease activating factor 1, APAF-1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.765927749314005	bayes_pls_golite062009
protein binding	0.62421304855934	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: