YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|493983, gi\|15...
Organism:	Escherichia coli
Length:	189 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|493983, gi|15....

Description	E-value	Query Range	Subject Range
gi\|77960493, gi\|... - gi\|77960493\|ref\|ZP_00824362.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Yersinia mollare...	158.0	[0..1]	[189..20]
gi\|165940210, gi... - gi\|89102782\|ref\|ZP_01175392.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Yersinia pestis ... gi\|108809517, gi... - gi\|108809517\|ref\|YP_653433.1\| periplasmic protein disulfide isomerase I [Yersinia pestis Antiqua], g... gi\|45434737, gi\|... - gi\|45439882\|ref\|NP_991421.1\| periplasmic protein disulfide isomerase I [Yersinia pestis biovar Micro... gi\|22127683, gi\|... - gi\|22127683\|ref\|NP_671106.1\| periplasmic protein disulfide isomerase I [Yersinia pestis KIM], gi\|219... gi\|115345848, gi... - gi\|218927237\|ref\|YP_002345112.1\| periplasmic protein disulfide isomerase I [Yersinia pestis CO92], g... gi\|51594375, gi\|... - gi\|51594375\|ref\|YP_068566.1\| periplasmic protein disulfide isomerase I [Yersinia pseudotuberculosis ... gi\|229682368, gi... - gi\|229900587\|ref\|ZP_04515712.1\| periplasmic protein disulfide isomerase I [Yersinia pestis Nepal516]... gi\|229836125, gi... - gi\|229836125\|ref\|ZP_04456293.1\| periplasmic protein disulfide isomerase I [Yersinia pestis Pestoides... gi\|229696229, gi... - gi\|229839863\|ref\|ZP_04460022.1\| periplasmic protein disulfide isomerase I [Yersinia pestis biovar Or... gi\|229690254, gi... - gi\|229841944\|ref\|ZP_04462099.1\| periplasmic protein disulfide isomerase I [Yersinia pestis biovar Or... Q66GG5\|Q66GG5_YERPS - Secreted thiol:disulfide interchange protein DsbA precursor - Yersinia pseudotuberculosis gi\|162351663, gi... - gi\|77633414\|ref\|ZP_00795546.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Yersinia pestis ... gi\|153947881, gi... - gi\|77630911\|ref\|ZP_00793497.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Yersinia pseudot... gi\|166011450, gi... - gi\|166011450\|ref\|ZP_02232348.1\| thiol:disulfide interchange protein DsbA [Yersinia pestis biovar Ant... gi\|165922040, gi... - gi\|165926180\|ref\|ZP_02222012.1\| thiol:disulfide interchange protein DsbA [Yersinia pestis biovar Ori... gi\|167402132, gi... - gi\|167402132\|ref\|ZP_02307609.1\| thiol:disulfide interchange protein DsbA [Yersinia pestis biovar Ant... gi\|166213669, gi... - gi\|166213669\|ref\|ZP_02239704.1\| thiol:disulfide interchange protein DsbA [Yersinia pestis biovar Ant... gi\|150260920, gi... - gi\|150260920\|ref\|ZP_01917648.1\| secreted thiol:disulfide interchange protein DsbA [Yersinia pestis C... gi\|145212823, gi... - gi\|145601127\|ref\|YP_001165203.1\| periplasmic protein disulfide isomerase I [Yersinia pestis Pestoide... DSBA_YERPE - Thiol:disulfide interchange protein DsbA OS=Yersinia pestis GN=dsbA PE=3 SV=1 gi\|167053961, gi... - gi\|167427034\|ref\|ZP_02318787.1\| thiol:disulfide interchange protein DsbA [Yersinia pestis biovar Med... gi\|166962840, gi... - gi\|167418846\|ref\|ZP_02310599.1\| thiol:disulfide interchange protein DsbA [Yersinia pestis biovar Ori... gi\|169752937, gi... - gi\|170026403\|ref\|YP_001722908.1\| periplasmic protein disulfide isomerase I [Yersinia pseudotuberculo... gi\|167470383 - gi\|167470383\|ref\|ZP_02335087.1\| thiol:disulfide interchange protein DsbA [Yersinia pestis FV-1] gi\|186696388, gi... - gi\|186893362\|ref\|YP_001870474.1\| periplasmic protein disulfide isomerase I [Yersinia pseudotuberculo...	157.0	[0..1]	[189..20]
gi\|77972096 - gi\|77972096\|ref\|ZP_00827675.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Yersinia frederi...	157.0	[0..1]	[189..20]
gi\|194418491, gi... - gi\|83569861\|ref\|ZP_00921310.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Shigella dysente...	157.0	[0..1]	[189..20]
gi\|2194076, gi\|2... - gi\|2194077\|pdb\|1FVJ\|B Chain B, The 2.06 Angstrom Structure Of The H32y Mutant Of The Disulfide Bond ...	157.0	[0..1]	[189..1]
gi\|238713474, gi... - gi\|77956894\|ref\|ZP_00820968.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Yersinia bercovi...	156.0	[0..1]	[189..20]
gi\|168775590, gi... - gi\|187768889\|gb\|EDU32733.1\| thiol:disulfide interchange protein DsbA [Escherichia coli O157:H7 str. ... gi\|168768140, gi... - gi\|189362598\|gb\|EDU81017.1\| thiol:disulfide interchange protein DsbA [Escherichia coli O157:H7 str. ... gi\|189375314, gi... - gi\|189375314\|gb\|EDU93730.1\| thiol:disulfide interchange protein DsbA [Escherichia coli O157:H7 str. ... gi\|168780758, gi... - gi\|189001471\|gb\|EDU70457.1\| thiol:disulfide interchange protein DsbA [Escherichia coli O157:H7 str. ... gi\|169891168, gi... - gi\|170083333\|ref\|YP_001732653.1\| periplasmic protein disulfide isomerase I [Escherichia coli str. K-... gi\|170022125, gi... - gi\|170022125\|ref\|YP_001727079.1\| periplasmic protein disulfide isomerase I [Escherichia coli ATCC 87... gi\|208807131, gi... - gi\|208807131\|ref\|ZP_03249468.1\| thiol:disulfide interchange protein DsbA [Escherichia coli O157:H7 s... gi\|195940267 - gi\|195940267\|ref\|ZP_03085649.1\| periplasmic protein disulfide isomerase I [Escherichia coli O157:H7 ... EG11297 - periplasmic protein disulfide isomerase I / Thiol:disulfide interchange protein, periplasmic; alkali... gi\|124501226, gi... - gi\|124527524\|ref\|ZP_01698989.1\| DSBA oxidoreductase [Escherichia coli B], gi\|124501226\|gb\|EAY48691.1... gi\|168750329, gi... - gi\|188015424\|gb\|EDU53546.1\| thiol:disulfide interchange protein DsbA [Escherichia coli O157:H7 str. ... gi\|189364979, gi... - gi\|189364979\|gb\|EDU83395.1\| thiol:disulfide interchange protein DsbA [Escherichia coli O157:H7 str. ... gi\|168755523, gi... - gi\|189357226\|gb\|EDU75645.1\| thiol:disulfide interchange protein DsbA [Escherichia coli O157:H7 str. ... DSBA_ECO57 - Thiol:disulfide interchange protein DsbA OS=Escherichia coli O157:H7 GN=dsbA PE=3 SV=1 gi\|188491865, gi... - gi\|75513990\|ref\|ZP_00736343.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... EG11297 - periplasmic protein disulfide isomerase I / Thiol:disulfide interchange protein, periplasmic; alkali... gi\|73857843, gi\|... - gi\|74314366\|ref\|YP_312785.1\| periplasmic protein disulfide isomerase I [Shigella sonnei Ss046], gi\|7... gi\|218707486, gi... - gi\|218707486\|ref\|YP_002415005.1\| periplasmic protein disulfide isomerase I [Escherichia coli UMN026]... gi\|15804445, gi\|... - gi\|15804445\|ref\|NP_290485.1\| periplasmic protein disulfide isomerase I [Escherichia coli O157:H7 EDL... gi\|75238303, gi\|... - gi\|75238303\|ref\|ZP_00722302.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|192925589, gi... - gi\|75255031\|ref\|ZP_00726943.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... DSBA_ECOLI - Thiol:disulfide interchange protein dsbA precursor - Escherichia coli gi\|81247616, gi\|... - gi\|82546205\|ref\|YP_410152.1\| periplasmic protein disulfide isomerase I [Shigella boydii Sb227], gi\|8... gi\|89110167, gi\|... - gi\|89110167\|ref\|AP_003947.1\| periplasmic protein disulfide isomerase I [Escherichia coli str. K-12 s... gi\|194420904, gi... - gi\|83584515\|ref\|ZP_00923192.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|208821648, gi... - gi\|208821648\|ref\|ZP_03261968.1\| thiol:disulfide interchange protein DsbA [Escherichia coli O157:H7 s... gi\|187428800, gi... - gi\|75176754\|ref\|ZP_00696882.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Shigella boydii ... gi\|208735795, gi... - gi\|208814518\|ref\|ZP_03255847.1\| thiol:disulfide interchange protein DsbA [Escherichia coli O157:H7 s... gi\|13364259, gi\|... - gi\|15834037\|ref\|NP_312810.1\| periplasmic protein disulfide isomerase I [Escherichia coli O157:H7 str... gi\|209914591, gi... - gi\|209921332\|ref\|YP_002295416.1\| periplasmic protein disulfide isomerase I [Escherichia coli SE11], ... gi\|110617003, gi... - gi\|110807455\|ref\|YP_690975.1\| periplasmic protein disulfide isomerase I [Shigella flexneri 5 str. 84... gi\|209400816, gi... - gi\|209400816\|ref\|YP_002273372.1\| thiol:disulfide interchange protein DsbA [Escherichia coli O157:H7 ... gi\|194411509, gi... - gi\|75208258\|ref\|ZP_00708618.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|218363188, gi... - gi\|218556419\|ref\|YP_002389333.1\| periplasmic protein disulfide isomerase I [Escherichia coli IAI1], ... gi\|190900508, gi... - gi\|75227234\|ref\|ZP_00714032.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|217321352, gi... - gi\|217325131\|ref\|ZP_03441215.1\| thiol:disulfide interchange protein DsbA [Escherichia coli O157:H7 s... gi\|157155214, gi... - gi\|75188595\|ref\|ZP_00701862.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|218701440, gi... - gi\|218701440\|ref\|YP_002409069.1\| periplasmic protein disulfide isomerase I [Escherichia coli IAI39],... gi\|157163329, gi... - gi\|75197736\|ref\|ZP_00707806.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Escherichia coli... gi\|218697574, gi... - gi\|218697574\|ref\|YP_002405241.1\| periplasmic protein disulfide isomerase I [Escherichia coli 55989],... gi\|238902928, gi... - gi\|238902928\|ref\|YP_002928724.1\| periplasmic protein disulfide isomerase I [Escherichia coli BW2952]... gi\|251787125, gi... - gi\|251787125\|ref\|YP_003001429.1\| hypothetical protein B21_03695 [Escherichia coli BL21], gi\|24237939... gi\|254163812, gi... - gi\|254163812\|ref\|YP_003046920.1\| periplasmic protein disulfide isomerase I [Escherichia coli B str. ... gi\|254290562, gi... - gi\|254290562\|ref\|YP_003056310.1\| periplasmic protein disulfide isomerase I [Escherichia coli BL21(DE... gi\|254595251, gi... - gi\|254795851\|ref\|YP_003080688.1\| periplasmic protein disulfide isomerase I [Escherichia coli O157:H7...	156.0	[0..1]	[189..20]
gi\|238726144, gi... - gi\|77976787\|ref\|ZP_00832258.1\| COG0526: Thiol-disulfide isomerase and thioredoxins [Yersinia interme...	156.0	[0..1]	[189..20]
gi\|81243115, gi\|... - gi\|82778967\|ref\|YP_405316.1\| periplasmic protein disulfide isomerase I [Shigella dysenteriae Sd197],...	155.0	[0..1]	[189..20]
DSBA_ECOL6 - Thiol:disulfide interchange protein DsbA OS=Escherichia coli O6 GN=dsbA PE=3 SV=1 DSBA_ECOL6 - Thiol:disulfide interchange protein DsbA OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UP... gi\|115515258, gi... - gi\|117626134\|ref\|YP_859457.1\| periplasmic protein disulfide isomerase I [Escherichia coli APEC O1], ... gi\|218692147, gi... - gi\|218692147\|ref\|YP_002400359.1\| periplasmic protein disulfide isomerase I [Escherichia coli ED1a], ... gi\|91074978, gi\|... - gi\|91213404\|ref\|YP_543390.1\| periplasmic protein disulfide isomerase I [Escherichia coli UTI89], gi\|... gi\|218367705, gi... - gi\|218560936\|ref\|YP_002393849.1\| periplasmic protein disulfide isomerase I [Escherichia coli S88], g... DSBA_ECO27 - Thiol:disulfide interchange protein DsbA OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=dsb... gi\|227885407, gi... - gi\|227885407\|ref\|ZP_04003212.1\| periplasmic protein disulfide isomerase I [Escherichia coli 83972], ... gi\|1040723 - gi\|1040723\|emb\|CAA90910.1\| DsbA protein [Escherichia coli] DSBA_ECO27 - Thiol:disulfide interchange protein dsbA OS=Escherichia coli O127:H6 GN=dsbA PE=3 SV=1 gi\|237702888, gi... - gi\|237702888\|ref\|ZP_04533369.1\| periplasmic protein disulfide isomerase I [Escherichia sp. 3_2_53FAA...	155.0	[0..1]	[189..20]

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Predicted Domain #1

Region A:
Residues: [1-189]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQYEDGKQYT TLEKPVAGAP QVLEFFSFFC PHCYQFEEVL HISDNVKKKL PEGVKMTKYH  60
   61 VNFMGGDLGK DLTQAWAVAM ALGVEDKVTV PLFEGVQKTQ TIRSASDIRD VFINAGIKGE 120
  121 EYDAAWNSFV VKSLVAQQEK AAADVQLRGV PAMFVNGKYQ LNPQGMDTSN MDVFVQQYAD 180
  181 TVKYLSEKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.69897
Match:	1a23A
Description:	SOLUTION NMR STRUCTURE OF REDUCED DSBA FROM ESCHERICHIA COLI, MINIMIZED AVERAGE STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein disulfide isomerase activity	1.48801287843472	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds	1.48801287843472	bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups	1.37876060576659	bayes_pls_golite062009
catalytic activity	1.04263226837398	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	0.25957505753521	bayes_pls_golite062009
isomerase activity	0.24662332270942	bayes_pls_golite062009
disulfide oxidoreductase activity	0.22354310938224	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: