YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|2554779, gi\|2...
Organism:	Homo sapiens
Length:	169 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|2554779, gi|2....

Description	E-value	Query Range	Subject Range
gi\|31419802 - gi\|31419802\|gb\|AAH53392.1\| Btk protein [Mus musculus]	143.0	[0..1]	[169..2]
gi\|74007950 - gi\|74007950\|ref\|XP_861687.1\| PREDICTED: similar to Bruton agammaglobulinemia tyrosine kinase isoform...	142.0	[0..1]	[169..2]
gi\|114689445 - gi\|114689445\|ref\|XP_001138895.1\| PREDICTED: Bruton agammaglobulinemia tyrosine kinase isoform 3 [Pan...	141.0	[0..1]	[169..2]
gi\|33304137 - gi\|33304137\|gb\|AAQ02576.1\| Bruton agammaglobulinemia tyrosine kinase [synthetic construct]	141.0	[0..1]	[169..2]
gi\|575890 - gi\|575890\|gb\|AAC51347.1\| Bruton's agammaglobulinemia tyrosine kinase [Homo sapiens]	141.0	[0..1]	[169..2]

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Predicted Domain #1

Region A:
Residues: [1-169]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAVILESIFL KRSQQKKKTS PLNFKKCLFL LTVHKLSYYE YDFERGRRGS KKGSIDVEKI  60
   61 TCVETVVPEK NPPPERQIPR RGEESSEMEQ ISIIERFPYP FQVVYDEGPL YVFSPTEELR 120
  121 KRWIHQLKNV IRYNSDLVQK YHPCFWIDGQ YLCCSQTAKN AMGCQILEN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.221849
Match:	1bwnA
Description:	Bruton's tyrosine kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.597587183571285	bayes_pls_golite062009
protein binding	0.29116370406325	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: