YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|494292, gi\|49...
Organism:	Escherichia coli
Length:	185 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|494292, gi|49....

Description	E-value	Query Range	Subject Range
gi\|223826 - gi\|223826\|prf\|\|1001196A toxin,cholera	285.0	[0..1]	[185..22]
gi\|3062901 - gi\|3062901\|dbj\|BAA25725.1\| heat-labile enterotoxin A subunit [Escherichia coli]	271.0	[0..1]	[185..22]
gi\|808899 - gi\|808899\|dbj\|BAA06288.1\| cholera toxin [Vibrio cholerae O37] gi\|254226671, gi... - gi\|254226671\|ref\|ZP_04920249.1\| cholera enterotoxin, A subunit [Vibrio cholerae V51], gi\|225354645\|r... gi\|18448889, gi\|... - gi\|18448891\|gb\|AAL69945.1\| CtxA [Vibrio cholerae], gi\|18448889\|gb\|AAL69944.1\| CtxA [Vibrio cholerae]... gi\|121730328, gi... - gi\|121730328\|ref\|ZP_01682692.1\| cholera enterotoxin, A subunit [Vibrio cholerae V52], gi\|121627920\|g...	271.0	[0..1]	[185..22]
gi\|227117915, gi... - gi\|227119922\|ref\|YP_002821817.1\| cholera enterotoxin, A subunit [Vibrio cholerae O395], gi\|227117915... gi\|254844291, gi... - gi\|254848586\|ref\|ZP_05237936.1\| cholera toxin A protein [Vibrio cholerae MO10], gi\|254844291\|gb\|EET2... gi\|124117655, gi... - gi\|153224387\|ref\|ZP_01954422.1\| cholera enterotoxin, A subunit [Vibrio cholerae MAK 757], gi\|1241176... gi\|153823865, gi... - gi\|229509627\|ref\|ZP_04399109.1\| enterotoxin A subunit (NAD(+)--diphthamide ADP- ribosyltransferase) ... CHTA_VIBCH - Cholera enterotoxin subunit A OS=Vibrio cholerae GN=ctxA PE=1 SV=1 gi\|808901 - gi\|808901\|dbj\|BAA06290.1\| cholera toxin [Vibrio cholerae O139] gi\|15825397, gi\|... - gi\|23305931\|gb\|AAN17351.1\| CtxA [Vibrio phage CTX], gi\|23305924\|gb\|AAN17345.1\| CtxA [Vibrio phage CT... gi\|229605802, gi... - gi\|229605802\|ref\|YP_002876506.1\| enterotoxin A subunit (NAD(+)--diphthamide ADP- ribosyltransferase)... CHTA_VIBCH - Cholera enterotoxin subunit A OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N1696... gi\|229518481, gi... - gi\|229518481\|ref\|ZP_04407925.1\| enterotoxin A subunit (NAD(+)--diphthamide ADP- ribosyltransferase) ...	271.0	[0..1]	[185..22]
gi\|20502729 - gi\|20502729\|gb\|AAM22586.1\|AF390572_1 cholera toxin A subunit [Vibrio cholerae O27] tr\|Q8L356\|Q8L356... - Cholera toxin A subunit OS=Vibrio cholerae O27 GN=ctxA PE=4 SV=1	271.0	[0..1]	[185..22]
gi\|88687062 - gi\|88687062\|emb\|CAJ13819.1\| non toxic mutant of heat labile enterotoxin A subunit precursot [Escheri...	268.0	[0..1]	[185..22]

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Predicted Domain #1

Region A:
Residues: [1-185]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLYRADSRPP DEIKRSGGLM PRGHNEYFDR GTQMNINLYD HARGTQTGFV RYDDGYVSTS  60
   61 LSLRSAHLAG QSILSGYSTY YIYVIATAPN MFNVNDVLGV YSPHPYEQEV SALGGIPYSQ 120
  121 IYGWYRVNFG VIDERLHRNR EYRDRYYRNL NIAPAEDGYR LAGFPPDHQA WREEPWIHHA 180
  181 PQGCG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	71.30103
Match:	1lt4A
Description:	Heat-labile toxin, A-chain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.35655888612093	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: