YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|20521674
Organism:	Homo sapiens
Length:	523 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|20521674.

Description	E-value	Query Range	Subject Range
gi\|37360118 - gi\|37360118\|dbj\|BAC98037.1\| mKIAA0840 protein [Mus musculus]	4.0E-59	[8..515]	[8..515]
gi\|109466245, gi... - gi\|157818663\|ref\|NP_001102015.1\| F-box and leucine-rich repeat protein 7 [Rattus norvegicus], gi\|149...	7.0E-53	[37..515]	[5..483]
gi\|109076751 - gi\|109076751\|ref\|XP_001087468.1\| PREDICTED: F-box and leucine-rich repeat protein 7 isoform 2 [Macac... gi\|208967817 - gi\|208967817\|dbj\|BAG72554.1\| F-box and leucine-rich repeat protein 7 [synthetic construct] gi\|114599010 - gi\|114599010\|ref\|XP_001148598.1\| PREDICTED: F-box and leucine-rich repeat protein 7 isoform 2 [Pan t... FBXL7 - F-box and leucine-rich repeat protein 7	1.0E-52	[37..515]	[5..483]
gi\|50734604 - gi\|50734604\|ref\|XP_426048.1\| PREDICTED: similar to mKIAA0840 protein [Gallus gallus]	2.0E-51	[75..515]	[79..519]
gi\|113535187, gi... - gi\|50904693\|ref\|XP_463835.1\| putative CLAVATA1 receptor kinase [Oryza sativa (japonica cultivar-grou...	9.0E-50	[13..522]	[78..587]
gi\|90399332 - gi\|90399332\|emb\|CAH68341.1\| H0313F03.16 [Oryza sativa (indica cultivar-group)]	2.0E-49	[13..521]	[215..702]

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Predicted Domain #1

Region A:
Residues: [1-140]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSRRAGFPRA ERAGRAPQLW SVPGDGGHDG YRMGANNGKQ YGSEGKGSSS ISSDVSSSTD  60
   61 HTPTKAQKNV ATSEDSDLSM RTLSTPSPAL ICPPNLPGFQ NGRGSSTSSS SITGETVAMV 120
  121 HSPPPTRLTH PLIRLASRPQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [141-421]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KEQASIDRLP DHSMVQIFSF LPTNQLCRCA RVCRRWYNLA WDPRLWRTIR LTGETINVDR  60
   61 ALKVLTRRLC QDTPNVCLML ETVTVSGCRR LTDRGLYTIA QCCPELRRLE VSGCYNISNE 120
  121 AVFDVVSLCP NLEHLDVSGC SKVTCISLTR EASIKLSPLH GKQISIRYLD MTDCFVLEDE 180
  181 GLHTIAAHCT QLTHLYLRRC VRLTDEGLRY LVIYCASIKE LSVSDCRFVS DFGLREIAKL 240
  241 ESRLRYLSIA HCGRVTDVGI RYVAKYCSKL RYLNARGCEG I

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	7.30103
Match:	1fqvA
Description:	Skp2; Cyclin A/CDK2-associated p19, Skp2
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [422-523]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TDHGVEYLAK NCTKLKSLDI GKCPLVSDTG LECLALNCFN LKRLSLKSCE SITGQGLQIV  60
   61 AANCFDLQTL NVQDCEVSVE ALRFVKRHCK RCVIEHTNPA FF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.154902
Match:	1fs2A
Description:	Skp2; Cyclin A/CDK2-associated p19, Skp2
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits