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Any process that stops, prevents or reduces the frequency, rate or extent of cell death by apoptosis. Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. The process by which the anatomical structures of the nephron are generated and organized. Morphogenesis pertains to the creation of form. A nephron is the functional unit of the kidney. A form of programmed cell death that begins when a cell receives internal or external signals that trigger the activity of proteolytic caspases, proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing (but maintenance of its integrity until the final stages of the process), and ends with the death of the cell. Any process that modulates the occurrence or rate of cell death by apoptosis. Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptosis that contributes to the shaping of the nephron. The process by which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells. Any process that stops, prevents or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptosis that contributes to the shaping of the nephron in the metanephros. Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis. Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptosis that contributes to the shaping of the nephron. The process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis
Acc: GO:0072040
Aspect: Biological Process
Desc: Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptosis that contributes to the shaping of the nephron.
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0072040 - negative regulation of mesenchymal stem cell apoptosis involved in nephron morphogenesis (interactive image map)
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