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Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together. That part of the nuclear content other than the chromosomes or the nucleolus. Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus. A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: MAML3-RBP-Jkappa-ICN1 complex
Acc: GO:0071179
Aspect: Cellular Component
Desc: A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
Synonyms:
  • MAML3-RBP-Jkappa-Notch1 complex
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0071179 - MAML3-RBP-Jkappa-ICN1 complex (interactive image map)
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Created and Maintained by: Michael Riffle