GO TERM SUMMARY
|
Name: |
BRCA1-C complex |
Acc: |
GO:0070533 |
Aspect: |
Cellular Component |
Desc: |
A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint. |
|
|
INTERACTIVE GO GRAPH
|