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The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Any process that modulates the rate or extent of progression through the cell cycle. A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase. Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. A cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state. The transition from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of G0 to G1 transition
Acc: GO:0070317
Aspect: Biological Process
Desc: A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.
Synonyms:
  • maintenance of G0 phase
  • maintenance of G0 arrest
Proteins in PDR annotated with:
   This term: 1 [Search]
   Term or descendants: 1 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0070317 - negative regulation of G0 to G1 transition (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle