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Any process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression. Any cellular process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process by which RNA molecules inactivate expression of target genes. Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process by which RNA molecules inactivate expression of target genes. Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression. Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger mRNA degradation or negatively regulate translation. Any process that decreases the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression. Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. Any process by which RNA molecules inactivate expression of target genes. The inactivation of gene expression by a posttranscriptional mechanism.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of gene silencing by miRNA
Acc: GO:0060965
Aspect: Biological Process
Desc: Any process that decreases the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060965 - negative regulation of gene silencing by miRNA (interactive image map)
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Created and Maintained by: Michael Riffle