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The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell. The process whereby a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries. The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell. The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell. The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: Notch signaling pathway involved in arterial endothelial cell fate commitment
Acc: GO:0060853
Aspect: Biological Process
Desc: The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060853 - Notch signaling pathway involved in arterial endothelial cell fate commitment (interactive image map)

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