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The formation of the ectoderm, mesoderm and endoderm during gastrulation. The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt an endoderm fate. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of a mesodermal fate. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt a mesoderm fate. The commitment of cells to specific cell fates of the endoderm, ectoderm and mesoderm as a part of gastrulation. The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment
Acc: GO:0060797
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt a mesoderm fate.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 0


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060797 - transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment (interactive image map)
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