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Any process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression. Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript. Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence. Any transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation. Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism. The inactivation of gene expression by a posttranscriptional mechanism. Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: regulation of posttranscriptional gene silencing
Acc: GO:0060147
Aspect: Biological Process
Desc: Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 4 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0060147 - regulation of posttranscriptional gene silencing (interactive image map)

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