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Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell. Any process that prevents the activation of the directed movement of norepinephrine into a cell. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell. The directed movement of norepinephrine into, out of, within or between cells by means of some external agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. Any process that modulates the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of amines into, out of, within or between cells by means of some external agent such as a transporter or pore. The uptake of catecholamine neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters. Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell. Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell. The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: negative regulation of norepinephrine uptake
Acc: GO:0051622
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell.
Synonyms:
  • negative regulation of levarterenol uptake
  • downregulation of norepinephrine uptake
  • down-regulation of norepinephrine uptake
  • negative regulation of noradrenaline uptake
  • negative regulation of norepinephrine import
  • down regulation of norepinephrine uptake
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051622 - negative regulation of norepinephrine uptake (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle